Hypergravity Load Modulates Acetaminophen Nephrotoxicity via Endoplasmic Reticulum Stress in Association with Hepatic microRNA-122 Expression

Autor: Sang-Gil Lee, Hongmin Wu, Choong-Sik Oh, Sang-Geon Kim

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4901, p 4901 (2021)

Hypergravity conditions may subject the kidney to intrinsic stress and lead to hemodynamic kidney dysfunction. However, the mechanisms underlying this phenomenon remain unclear. Accumulation of unfolded proteins in the endoplasmic reticulum (i.e., ER

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6408ea0be8aecce9fb852939f3f0e1

Corrigendum: A load of mice to hypergravity causes AMPKα repression with liver injury, which is overcome by preconditioning loads via Nrf2

Autor: Sang Gil Lee, So Won Chung, Chan Gyu Lee, Choong Sik Oh, Hong Min Wu, Sang Geon Kim

Publikováno v: Scientific Reports

An understanding of the effects of hypergravity on energy homeostasis is necessary in managing proper physiological countermeasures for aerospace missions. This study investigated whether a single or multiple load(s) of mice to hypergravity has an ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad1f4725fb9ae66a85a7ba4120805ab
http://europepmc.org/articles/PMC5050539

Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production

Autor: Hyun Soo Kim, Choong Sik Oh, Gun Yoon

Publikováno v: Oncotarget

// Gun Yoon 1 , Choong Sik Oh 2 and Hyun-Soo Kim 3 1 Department of Obstetrics and Gynecology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan-si, Gyeongsangnam-do, Republic of Korea 2 Aerospace Medici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea44d89e62ac07b88a6cac0eee57538
https://pubmed.ncbi.nlm.nih.gov/27174912

A load of mice to hypergravity causes AMPKα repression with liver injury, which is overcome by preconditioning loads via Nrf2

Autor: Choong Sik Oh, Sang Geon Kim, Sang Gil Lee, So Won Chung, Chan Gyu Lee, Hong Min Wu

Publikováno v: SCIENTIFIC REPORTS(5)

An understanding of the effects of hypergravity on energy homeostasis is necessary in managing proper physiological countermeasures for aerospace missions. This study investigated whether a single or multiple load(s) of mice to hypergravity has an ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d42c730effe78082423c0f620aa12cd