Zobrazeno 1 - 10
of 672
pro vyhledávání: '"Choon Sik, Park"'
Autor:
Jong-Uk Lee, Jong-Sook Park, Eunjeong Seo, Jin Seol Kim, Hae Ung Lee, Yongjin Chang, Jai Seong Park, Choon-Sik Park
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Purpose The extent of honeycombing and reticulation predict the clinical prognosis of IPF. Emphysema, consolidation, and ground glass opacity are visible in HRCT scans. To date, there have been few comprehensive studies that have used these
Externí odkaz:
https://doaj.org/article/cf6109a28d104647b8f22e784a02c59f
Autor:
Hyun-Ji Jang, Hye-Young Min, Yun Pyo Kang, Hye-Jin Boo, Jisung Kim, Jee Hwan Ahn, Seung Ho Oh, Jin Hwa Jung, Choon-Sik Park, Jong-Sook Park, Seog-Young Kim, Ho-Young Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Tobacco smoking (TS) is implicated in lung cancer (LC) progression through the development of metabolic syndrome. However, direct evidence linking metabolic syndrome to TS-mediated LC progression remains to be established. Our findings demon
Externí odkaz:
https://doaj.org/article/ce50cebb753f46e7b12fda546522af2e
Autor:
Hye-Jin Boo, Hye-Young Min, Su Jung Hwang, Hyo-Jong Lee, Jae-Won Lee, Sei-Ryang Oh, Choon-Sik Park, Jong-Sook Park, You Mie Lee, Ho-Young Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 6, Pp 1131-1144 (2023)
Abstract The renin-angiotensin (RA) system has been implicated in lung tumorigenesis without detailed mechanistic elucidation. Here, we demonstrate that exposure to the representative tobacco-specific carcinogen nitrosamine 4-(methylnitrosamino)-1-(3
Externí odkaz:
https://doaj.org/article/dc30c8eff1d24fa5b014bc318d4499e6
Publikováno v:
The Korean Journal of Internal Medicine, Vol 37, Iss 5, Pp 979-988 (2022)
Background/Aims Neutrophilia is frequently observed in bronchoalveolar lavage fluid (BALF) of idiopathic pulmonary fibrosis (IPF) patients. Granulocyte colony-stimulating factor (G-CSF) is a potent neutrophil-activating glycoprotein. However, the cli
Externí odkaz:
https://doaj.org/article/e0842b0023bf430e859fc9216dd4ee52
Autor:
Seung Yeob Hyun, Hye-Young Min, Ho Jin Lee, Jaebeom Cho, Hye-Jin Boo, Myungkyung Noh, Hyun-Ji Jang, Hyo-Jong Lee, Choon-Sik Park, Jong-Sook Park, Young Kee Shin, Ho-Young Lee
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role of Ninj1 in the contex
Externí odkaz:
https://doaj.org/article/b4f3869aff0848ca82a6e321d2e20bea
Autor:
Min-Hye Kim, Hun Soo Chang, Jong-Uk Lee, Ji-Su Shim, Jong-Sook Park, Young-Joo Cho, Choon-Sik Park
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Asthma exacerbation threatens patient's life. Several genetic studies have been conducted to determine the risk factors for asthma exacerbation, but this information is still lacking. We aimed to determine whether genetic variants
Externí odkaz:
https://doaj.org/article/4dc08e89ad5742dfa221284ab44cf9fa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10182 (2023)
Novel genetic and epigenetic factors involved in the development and prognosis of idiopathic pulmonary fibrosis (IPF) have been identified. We previously observed that erythrocyte membrane protein band 4.1-like 3 (EPB41L3) increased in the lung fibro
Externí odkaz:
https://doaj.org/article/912289e2f8824def85caacb6f9bf1e83
Autor:
Jae-Woo Jung, Hae-Sim Park, Choon-Sik Park, Sang-Heon Cho, Inseon S. Choi, Hee-Bom Moon, Soon Seog Kwon, Ho Joo Yoon, Jung Won Park, Jong-Myung Lee, Dong-Chull Choi, Byoung Whui Choi
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss 4, Pp 1001-1013 (2021)
Background/Aims Omalizumab is the first biologic known to be effective in patients with severe allergic asthma. Methods This study was conducted as a multicenter, single-group, open trial to evaluate the improvement in the quality of life with the ad
Externí odkaz:
https://doaj.org/article/266209b769be40d4bfb85761b6f6af6c
Autor:
Ji-Hye Son, Jong-Uk Lee, Susie Chin, Eun-Suk Go, Jai-Seong Park, Hwa-Kyun Shin, Hun Soo Chang, Jong-Sook Park, Choon-Sik Park
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss 4, Pp 914-923 (2021)
Background/Aims Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a major regulator of Wnt signaling, which is involved in fibroblast dysfunction. Because its role has not been evaluated in idiopathic pulmonary fibrosis (IPF), we examined the
Externí odkaz:
https://doaj.org/article/8650283cca794a47a23f688cea7f2ab0
Autor:
Mi-Kyeong Kim, Hae-Sim Park, Choon-Sik Park, Soung-Jun Min, Frank C. Albers, Steven W. Yancey, Bhabita Mayer, Namhee Kwon
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss 2, Pp 362-370 (2021)
Background/Aims The efficacy and safety of mepolizumab in patients with severe eosinophilic asthma has been evaluated in a global clinical trial programme. This post hoc analysis assesses the efficacy and safety of mepolizumab in Korean patients. Met
Externí odkaz:
https://doaj.org/article/231f886fb296415ea39634ca177fb176