Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Choo Hock Tan"'
Autor:
Rebecca J. Edge, Amy E. Marriott, Emma L. Stars, Rohit N. Patel, Mark C. Wilkinson, Lloyd D.W. King, Julien Slagboom, Choo Hock Tan, Kavi Ratanabanangkoon, Simon J. Draper, Stuart Ainsworth
Publikováno v:
Toxicon: X, Vol 23, Iss , Pp 100204- (2024)
Snakebite is a major global health concern, for which antivenom remains the only approved treatment to neutralise the harmful effects of the toxins. However, some medically important toxins are poorly immunogenic, resulting in reduced efficacy of the
Externí odkaz:
https://doaj.org/article/7786c6bea5b54487a9ec625049f911c8
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Most elapid snakes produce venoms that contain alpha-neurotoxins (α-NTXs), which are proteins that cause post-synaptic blockade and paralysis in snakebite envenoming. However, existing elapid antivenoms are known for their low potency
Externí odkaz:
https://doaj.org/article/672d1acf91a147418298b741b9bc9f43
Publikováno v:
Toxins, Vol 15, Iss 9, p 585 (2023)
The venom proteome of Temple Pit Viper (Tropidolaemus wagleri) is unique among pit vipers, characterized by a high abundance of a neurotoxic peptide, waglerin. To further explore the genetic diversity of its toxins, the present study de novo assemble
Externí odkaz:
https://doaj.org/article/5360b672c5934bf182bce1dd9c701110
Publikováno v:
Toxins, Vol 15, Iss 5, p 315 (2023)
In Southeast Asia, the Malayan Pit Viper (Calloselasma rhodostoma) is a venomous snake species of medical importance and bioprospecting potential. To unveil the diversity of its toxin genes, this study de novo assembled and analyzed the venom gland t
Externí odkaz:
https://doaj.org/article/ec887227ed524db3a222c3d1723cdf1a
Autor:
Andy Shing Seng Lim, Kae Yi Tan, Naeem H. Quraishi, Saud Farooque, Zahoor Ahmed Khoso, Kavi Ratanabanangkoon, Choo Hock Tan
Publikováno v:
Toxins, Vol 15, Iss 4, p 265 (2023)
Snakebite envenoming is a neglected tropical disease prevalent in South Asia. In Pakistan, antivenoms are commonly imported from India despite the controversy over their effectiveness. To solve the problem, the locals have developed the Pakistani Vip
Externí odkaz:
https://doaj.org/article/2f3e890283494f09b058df8db6a50bd5
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/ebebbd78cb8f4918860cf7bcd610a898
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2022)
Abstract King Cobra (Ophiophagus hannah) has a significant place in many cultures, and is a medically important venomous snake in the world. Envenomation by this snake is highly lethal, manifested mainly by neurotoxicity and local tissue damage. King
Externí odkaz:
https://doaj.org/article/03655db9c35e48c380cd547e2e565866
Autor:
Marco Stazi, Federico Fabris, Kae Yi Tan, Aram Megighian, Alessandro Rubini, Andrea Mattarei, Samuele Negro, Giorgia D'Este, Florigio Lista, Ornella Rossetto, Choo Hock Tan, Cesare Montecucco
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/bdb7dc1690df4088adc919f6d9cf31b3
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The Samar Cobra, Naja samarensis, is endemic to the southern Philippines and is a WHO-listed Category 1 venomous snake species of medical importance. Envenomation caused by N. samarensis results in neurotoxicity, while there is no species-specific an
Externí odkaz:
https://doaj.org/article/332d83e02fce411c9469e7a6171cb572
Publikováno v:
Toxins, Vol 14, Iss 12, p 860 (2022)
Naja nivea (Cape Cobra) is endemic to southern Africa. Envenoming by N. nivea is neurotoxic, resulting in fatal paralysis. Its venom composition, however, has not been studied in depth, and specific antivenoms against it remain limited in supply. App
Externí odkaz:
https://doaj.org/article/d28892c34509481692e3b6b99a7b3ab3