Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chontida Yarana"'
Autor:
Chontida Yarana, Chayodom Maneechote, Thawatchai Khuanjing, Benjamin Ongnok, Nanthip Prathumsap, Sirasa Thanasrisuk, Kovit Pattanapanyasat, Siriporn C. Chattipakorn, Nipon Chattipakorn
Publikováno v:
Current Research in Toxicology, Vol 5, Iss , Pp 100134- (2023)
Late-onset cardiomyopathy is becoming more common among cancer survivors, particularly those who received doxorubicin (DOXO) treatment. However, few clinically available cardiac biomarkers can predict an unfavorable cardiac outcome before cell death.
Externí odkaz:
https://doaj.org/article/2f0c72532b5142819763f23700ed3f79
Autor:
Chontida Yarana, Panjaree Siwaponanan, Chayodom Maneechote, Thawatchai Khuanjing, Benjamin Ongnok, Nanthip Prathumsap, Siriporn C. Chattipakorn, Nipon Chattipakorn, Kovit Pattanapanyasat
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13465 (2022)
Doxorubicin (DOXO)-induced cardiomyopathy (DIC) is a lethal complication in cancer patients. Major mechanisms of DIC involve oxidative stress in cardiomyocytes and hyperactivated immune response. Extracellular vesicles (EVs) mediate cell–cell commu
Externí odkaz:
https://doaj.org/article/de20801a00434b6c91b9f364849696be
Autor:
Chontida Yarana, Hannah Thompson, Luksana Chaiswing, D. Allan Butterfield, Heidi Weiss, Subbarao Bondada, Sara Alhakeem, Suriyan Sukati, Daret K. St. Clair
Publikováno v:
Redox Biology, Vol 26, Iss , Pp - (2019)
Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX
Externí odkaz:
https://doaj.org/article/98e908279b00465d8862dbf696cd086c
Autor:
Chontida Yarana, Daret K. St. Clair
Publikováno v:
Antioxidants, Vol 6, Iss 4, p 75 (2017)
The short- and long-term side effects of chemotherapy limit the maximum therapeutic dose and impair quality of life of survivors. Injury to normal tissues, especially chemotherapy-induced cardiomyopathy, is an unintended outcome that presents devasta
Externí odkaz:
https://doaj.org/article/4d4f918d4061418eb99d7caa98bebff4
Autor:
Luksana Chaiswing, Chontida Yarana, William St. Clair, Artak Tovmasyan, Ines Batinic-Haberle, Ivan Spasojevic, Daret St. Clair
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-16
We have employed a redox-active MnP (MnTnBuOE-2-PyP5+, Mn(III) meso-tetrakis (N-n-butoxyethylpyridinium-2-yl) porphyrin) frequently identified as superoxide dismutase mimic or BMX-001, to explore the redox status of normal ovarian cell in relation to
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Western blots indicating PYGB, PYGM, and PYGL are tissue-specific protein. PYGB is highly expressed in heart and brain. PYGM is highly expressed in skeletal muscle. PYGL is highly expressed in liver. Vinculin and tubulin were used as appropriate posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fea728dcda5d7f7f893dd10818d90b
https://doi.org/10.1158/1078-0432.22464719.v1
https://doi.org/10.1158/1078-0432.22464719.v1
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Western blots display PYGB, PYGM, and PYGL expression. A. EVs from mice treated with saline or DOX. B. PYGB in EVs and heart tissues from wild-type or MnSOD Tg mice treated with saline or DOX. C. PYGB in EVs and heart tissues from mice treated with M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd61faf3794f9b6c272feb12687f7c3
https://doi.org/10.1158/1078-0432.22464710.v1
https://doi.org/10.1158/1078-0432.22464710.v1
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Sucrose gradient isolation process for proteomics analysis. A. Diagram showing the process of EV isolation by sucrose gradient method. B. Western blots of EV markers, CD63 and CD81 of sucrose gradient fraction 1 to 5 (from the top to the bottom). C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52411e5ce76bed977078f08ddecb16d5
https://doi.org/10.1158/1078-0432.22464725.v1
https://doi.org/10.1158/1078-0432.22464725.v1
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Western blots confirming the existence of PYGB, PYGM, and PYGL in SAL_EVs and DOX_EVs after treatment with proteinase K. Cell lysate was used as a positive control for PYGB, PYGM and PYGL detection. IgG and albumin were measured as a reference for pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d262a9ef983c4733d0a56c262a0942
https://doi.org/10.1158/1078-0432.22464713
https://doi.org/10.1158/1078-0432.22464713
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Western blots of EV markers (CD63 and Alix) and endoplasmic reticulum marker (Calnexin) in SAL_EVs and DOX_EVs. The cell lysate was used as a positive control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e288d3cebb070c03033275fdbd7eb65
https://doi.org/10.1158/1078-0432.22464722
https://doi.org/10.1158/1078-0432.22464722