Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Chonlaphat Sukasem"'
Autor:
Chanarong Saechua, Tewarit Sarachana, Weerasak Chonchaiya, Pon Trairatvorakul, Wasana Yuwattana, Chayanit Poolcharoen, Montira Sangritdech, Thanit Saeliw, Marlieke Lisanne van Erp, Siriporn Sangsuthum, Natthakul Akarapredee, Sayanit Tipnoppanon, Rattanaporn Sukprasong, Patompong Satapornpong, Chalirmporn Atasilp, Chonlaphat Sukasem, Natchaya Vanwong
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study explores the association between genetic variations in the vitamin D pathway and autism spectrum disorder (ASD) susceptibility and severity in Thai children. A total of 276 participants, including 169 children with ASD and 107 hea
Externí odkaz:
https://doaj.org/article/b4ac9500a9a04a6592b5104248bc1af4
Autor:
Narumol Trachu, Thanyanan Reungwetwattana, Jennis Meanwatthana, Chonlaphat Sukasem, Teerapat Majam, Wacharapol Saengsiwaritt, Jiraphun Jittikoon, Wanvisa Udomsinprasert
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to measure relative telomere length (RTL) in blood leukocytes of advanced-stage NSCLC patients either with or without Osimertinib-induced ADRs and determine whether RTL could serve as a biomarker of Osimertinib-induced ADRs.
Externí odkaz:
https://doaj.org/article/31980476529c47eebb660187cb7ab449
Autor:
Shobana John, Sommon Klumsathian, Paravee Own‐eium, Angkana Charoenyingwattana, Jakris Eu‐ahsunthornwattana, Thanyachai Sura, Donniphat Dejsuphong, Piyamitr Sritara, Prin Vathesatogkit, Nartthawee Thongchompoo, Wiphaporn Thabthimthong, Nuttinee Teerakulkittipong, Wasun Chantratita, Chonlaphat Sukasem
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 10, Pp n/a-n/a (2024)
Abstract Next‐generation sequencing (NGS) has transformed pharmacogenomics (PGx), enabling thorough profiling of pharmacogenes using computational methods and advancing personalized medicine. The Thai Pharmacogenomic Database‐2 (TPGxD‐2) analyz
Externí odkaz:
https://doaj.org/article/b4a9ca5c6f634c789ebe1ba62ff2b8f6
Autor:
Gaidganok Sornsamdang, Patompong Satapornpong, Pimonpan Jinda, Thawinee Jantararoungtong, Napatrupron Koomdee, Therdpong Tempark, Jettanong Klaewsongkram, Ticha Rerkpattanapipat, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Kumutnart Chanprapaph, Wareeporn Disphanurat, Panlop Chakkavittumrong, Chutika Srisuttiyakorn, Yuttana Srinoulprasert, Shobana John, Mohitosh Biswas, Chonlaphat Sukasem
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background Allopurinol has been causing substantial morbidity and mortality particularly in Asian population by producing cutaneous adverse drug reactions (cADRs). Nonetheless, there are no data describing whether other genetics are a valid
Externí odkaz:
https://doaj.org/article/29c4a501e9b74a8faf9ce920ccb509c1
Autor:
Gaidganok Sornsamdang, John Shobana, Kumutnart Chanprapaph, Wasun Chantratita, Sasithorn Chotewutmontri, Preeyachat Limtong, Pichaya O-charoen, Chonlaphat Sukasem
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Behçet's disease (BD) manifests as an autoimmune disorder featuring recurrent ulcers and multi-organ involvement, influenced by genetic factors associated with both HLA and non-HLA genes, including TNF-α and ERAP1. The study investigated t
Externí odkaz:
https://doaj.org/article/0b981957f1a94e8fb0777e7219c9e74b
Autor:
Kanoot Jaruthamsophon, Pornsiri Sangmanee, Oradawan Plong‐on, Chariyawan Charalsawadi, Chonlaphat Sukasem, Areerat Hnoonual
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract Genetic screening for HLA‐B*15:02 before prescribing carbamazepine is standard practice to prevent severe cutaneous adverse reactions in Asian populations. These reactions are associated not only with this allele but also with closely rela
Externí odkaz:
https://doaj.org/article/550eaba2accc423587a46a44dae04519
Autor:
Shobana John, Sommon Klumsathian, Paravee Own‐eium, Jakris Eu‐ahsunthornwattana, Thanyachai Sura, Donniphat Dejsuphong, Piyamitr Sritara, Prin Vathesatogkit, Nartthawee Thongchompoo, Wiphaporn Thabthimthong, Nuttinee Teerakulkittipong, Wasun Chantratita, Chonlaphat Sukasem
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract Computational methods analyze genomic data to identify genetic variants linked to drug responses, thereby guiding personalized medicine. This study analyzed 942 whole‐genome sequences from the Electricity Generating Authority of Thailand (
Externí odkaz:
https://doaj.org/article/e3bb170d432048f7baaedacb3e35010a
Autor:
Mohitosh Biswas, Md. Shahadat Hossain, Tahsin Ahmed Rupok, Md. Sabbir Hossain, Chonlaphat Sukasem
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 4, Pp n/a-n/a (2024)
Abstract The aggregated risk of recurrent stroke in stroke/transient ischemic attack (TIA) patients carrying CYP2C19 LoF alleles who take clopidogrel has not been investigated recently, and the available research is limited. This study aimed to perfo
Externí odkaz:
https://doaj.org/article/faba2158f0a24039ae0c54de4c44eee6
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Autism spectrum disorder (ASD) may affect family and social life profoundly. Although there is no selective pharmacotherapy for ASD, the Food and Drug Administration (FDA) has recommended risperidone/aripiprazole to treat the associated symptoms of A
Externí odkaz:
https://doaj.org/article/a0744fb3edd040379608d2755b33b99d
Autor:
Waritda Pookmanee, Siriwan Thongthip, Mathirut Mungthin, Chonlaphat Sukasem, Jeeranut Tankanitlert, Pajaree Chariyavilaskul, Supeecha Wittayalertpanya
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24351- (2024)
Objectives: Primaquine is metabolized by the cytochrome P450-2D6 enzyme (CYP2D6) to an active primaquine-5,6-orthoquinone (POQ). No relationships of CYP2D6 polymorphisms with the pharmacokinetics of primaquine and POQ were reported in the Thai popula
Externí odkaz:
https://doaj.org/article/79f2407e76e748c5ac5650b56f2280ab