Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chongyin Han"'
Autor:
Xiaoqi Huang, Chongyin Han, Jiayuan Zhong, Jiaqi Hu, Yabin Jin, Qinqin Zhang, Wei Luo, Rui Liu, Fei Ling
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Deterioration of normal intestinal epithelial cells is crucial for colorectal tumorigenesis. However, the process of epithelial cell deterioration and molecular networks that contribute to this process remain unclear. Methods Sing
Externí odkaz:
https://doaj.org/article/62949099f1be4f34bd60b623bd5439af
Autor:
Chongyin Han, Jiayuan Zhong, Qinqin Zhang, Jiaqi Hu, Rui Liu, Huisheng Liu, Zongchao Mo, Pei Chen, Fei Ling
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1189-1197 (2022)
The dynamic network biomarker (DNB) method has advanced since it was first proposed. This review discusses advances in the DNB method that can identify the dynamic change in the expression signature related to the critical time point of disease progr
Externí odkaz:
https://doaj.org/article/bf4f36b1bcdf46dcb4bf2cae40ecbe1e
Autor:
Huisheng Liu, JiaYuan Zhong, JiaQi Hu, ChongYin Han, Rui Li, XueQing Yao, ShiPing Liu, Pei Chen, Rui Liu, Fei Ling
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 495-506 (2021)
Increasing evidence indicates that mature B cells in the adjacent tumor tissue, both as an intermediate state, are vital in advanced colorectal cancer (CRC), which is associated with a low survival rate. Developing predictive biomarkers that detect t
Externí odkaz:
https://doaj.org/article/c2400cef392547dd86899464eb33ad93
Autor:
Zhiqiang Jiang, Yilin Huang, Piao Zhang, Chongyin Han, Yueer Lu, Zongchao Mo, Zhanyu Zhang, Xin Li, Sisi Zhao, Fuqiang Cai, Lizhen Huang, Chunbo Chen, Zhihong Shi, Yuhu Zhang, Fei Ling
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disease, and mild cognitive impairment (MCI) is a well-established risk factor for the development of dementia in PD. A growing body of evidence suggests that low express
Externí odkaz:
https://doaj.org/article/5d5daed15dd64eb597a02128c1be205c
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunotherapy has achieved positive clinical responses in various cancers. However, in advanced colorectal cancer (CRC), immunotherapy is challenging because of the deterioration of T-cell exhaustion, the mechanism of which is still unclear. In this
Externí odkaz:
https://doaj.org/article/49ec8e64330147a895f26420cdac81f8
Autor:
Yilin Huang, Huisheng Liu, Jiaqi Hu, Chongyin Han, Zhenggang Zhong, Wei Luo, Yuhu Zhang, Fei Ling
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Parkinson’s disease (PD) is the second most neurodegenerative disease in the world. T cell infiltration in the central nervous system (CNS) has provided insights that the peripheral immune cells participate in the pathogenesis of PD. However, the a
Externí odkaz:
https://doaj.org/article/2a410c6d17e04c9795e37a7f6aee55f5
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
A complex disease, especially cancer, always has pre-deterioration stage during its progression, which is difficult to identify but crucial to drug research and clinical intervention. However, using a few samples to find mechanisms that propel cancer
Externí odkaz:
https://doaj.org/article/3e4f512856b34d92b4d7b19d0cbfb76d
Autor:
Yueer Lu, Xiao Wang, Hang Yu, Jianlin Li, Zhiqiang Jiang, Bangwei Chen, Yueqi Lu, Wei Wang, Chongyin Han, Ying Ouyang, Lizhen Huang, Chunbo Chen, Weidong Tian, Fei Ling
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
How the human brain differs from those of non-human primates is largely unknown and the complex drivers underlying such differences at the genomic level remain unclear. In this study, we selected 243 brain-related genes, based on Gene Ontology, and i
Externí odkaz:
https://doaj.org/article/be2a9a1f8928415db6d995d22691ca61
Publikováno v:
Bioinformatics. 38:5398-5405
Motivation Catastrophic transitions are ubiquitous in the dynamic progression of complex biological systems; that is, a critical transition at which complex systems suddenly shift from one stable state to another occurs. Identifying such a critical p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3f81d741458b05e15fbd02746bcd58
https://doi.org/10.1093/bioinformatics/btac707
https://doi.org/10.1093/bioinformatics/btac707
Autor:
Xueqing Yao, Chongyin Han, Huisheng Liu, Jiaqi Hu, Jiayuan Zhong, ShiPing Liu, Rui Li, Rui Liu, Pei Chen, Fei Ling
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 22, Iss, Pp 495-506 (2021)
Molecular Therapy: Oncolytics, Vol 22, Iss, Pp 495-506 (2021)
Increasing evidence indicates that mature B cells in the adjacent tumor tissue, both as an intermediate state, are vital in advanced colorectal cancer (CRC), which is associated with a low survival rate. Developing predictive biomarkers that detect t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147f6d4e9bda4383772bd2a8e6cf22d4
http://europepmc.org/articles/PMC8433066
http://europepmc.org/articles/PMC8433066