Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chonglin Luo"'
Autor:
Stefanie E. Grund, Maria Polycarpou-Schwarz, Chonglin Luo, Stefan B. Eichmüller, Sven Diederichs
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 3, Pp 238-248 (2012)
Drosha is a key enzyme in microRNA biogenesis, generating the precursor miRNA (pre-miRNA) by excising the stem-loop embedded in the primary transcripts (pri-miRNA). The specificity for the pri-miRNAs and determination of the cleavage site are provide
Externí odkaz:
https://doaj.org/article/f9655ff8e963449aa9c9d7011464769e
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
We developed a single vector recombinant adeno-associated viral (rAAV) expression system for spatial and reversible control of polycistronic gene expression. Our approach (i) integrates the advantages of the tetracycline (Tet)-controlled transcriptio
Externí odkaz:
https://doaj.org/article/4bcfb1ac9b05400ca1063cb90d5ef8d0
Autor:
Yaqi, Li, Shaobo, Mo, Long, Zhang, Xiaoji, Ma, Xiang, Hu, Dan, Huang, Binbin, Lu, Chonglin, Luo, Haixiang, Peng, Sanjun, Cai, Weiqi, Sheng, Junjie, Peng
Publikováno v:
European Journal of Cancer. 169:198-209
Precise methods for risk stratification to guide adjuvant chemotherapy for stage III colon cancers are needed. Here, we combined circulating tumor DNA (ctDNA) with consensus molecular subtype (CMS) to improve risk stratification in stage III colon ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ceb60dcf146aab338b2c2936e0815b
https://doi.org/10.1016/j.ejca.2022.04.010
https://doi.org/10.1016/j.ejca.2022.04.010
Autor:
Stefan B. Eichmüller, Wolfram Osen, Tim Holland-Letz, Theresa Kordaß, Adriane Gardyan, Agnes Hotz-Wagenblatt, Chonglin Luo, Claudia E.M. Weber
Transfection of melanoma cells with small nucleotides; isolation of total RNA; reverse transcription and qPCR; luciferase reporter assay; Western blot analysis; bioinformatics; statistics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1271e435207d83f94f6db8ff7716cb69
https://doi.org/10.1158/0008-5472.22407488
https://doi.org/10.1158/0008-5472.22407488
Autor:
Stefan B. Eichmüller, Wolfram Osen, Tim Holland-Letz, Theresa Kordaß, Adriane Gardyan, Agnes Hotz-Wagenblatt, Chonglin Luo, Claudia E.M. Weber
In silico analysis of miR-339-3p targets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80833f7a5dc5841c34a4da3714e3083b
https://doi.org/10.1158/0008-5472.22407479
https://doi.org/10.1158/0008-5472.22407479
Autor:
Stefan B. Eichmüller, Wolfram Osen, Tim Holland-Letz, Theresa Kordaß, Adriane Gardyan, Agnes Hotz-Wagenblatt, Chonglin Luo, Claudia E.M. Weber
Fig. S1. Workflow for a functional screening approach to investigate miRNAs impacting on melanoma cell invasion; Fig. S2. Cell viability assay on 97 most effective miRNA candidates accelerating (A) or inhibiting (B) A375 invasion; Fig. S3. Invasive c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197f27072ef79f7e84ca11f0fb11a81d
https://doi.org/10.1158/0008-5472.22407491.v1
https://doi.org/10.1158/0008-5472.22407491.v1
Autor:
Jing Wu, Yiyi Yu, Shilong Zhang, Pengfei Zhang, Shan Yu, Wei Li, Yan Wang, Qian Li, Binbin Lu, Limeng Chen, Chonglin Luo, Haixiang Peng, Tianshu Liu, Yuehong Cui
Background Immune checkpoint inhibitors (ICIs) have significant clinical benefit for a subset of patients with gastrointestinal cancers including esophageal cancer, gastric cancer and colorectal cancer. However, it is difficult to predict which patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3d75702290f7acca3b8a02bb349995
https://doi.org/10.21203/rs.3.rs-2551844/v1
https://doi.org/10.21203/rs.3.rs-2551844/v1
Autor:
Ying Hao, Fei Gai, Chonglin Luo, Alia Abukiwan, Xueyuan Xiao, Dacheng He, Shuai Hao, Na Lv, Lingyun Huang, Stefan B. Eichmüller, Weiwei Huang
Publikováno v:
Science China Life Sciences. 61:541-549
Late-stage melanoma is refractory to current therapies. MicroRNAs (miRNAs) can modulate many physiological and pathological processes of melanoma. Studies have demonstrated that miR-137 acts as a tumor suppressor by inhibiting the proliferation of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ca3f54a3157be5381d926f4a32b286
https://doi.org/10.1007/s11427-017-9138-9
https://doi.org/10.1007/s11427-017-9138-9
Autor:
Adriane Gardyan, Theresa Kordaß, Chonglin Luo, Tim Holland-Letz, Agnes Hotz-Wagenblatt, Wolfram Osen, Stefan B. Eichmüller, Claudia E.M. Weber
Publikováno v:
Cancer Research. 76:3562-3571
Determinants of invasion and metastasis in cancer remain of great interest to define. Here, we report the definition of miR-339-3p as a novel tumor suppressive microRNA that blocks melanoma cell invasion without affecting cell survival. miR-339-3p wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b9dbea8953136f0898ce9d753b8e53
https://doi.org/10.1158/0008-5472.can-15-2932
https://doi.org/10.1158/0008-5472.can-15-2932
Autor:
Hongyang Wang, Ziliang Qian, Mao Mao, Chi-Chung Chan, Douglas D. Fang, Hongye Sun, Chen Shuhui, Xiaowei Xu, Qiang Xu, Yuxin Qin, Yuhong Shen, Shuqun Yang, Yexiong Tan, Chonglin Luo, Guan Wang, Qingyang Gu
Publikováno v:
Oncotarget
Hepatocellular carcinoma (HCC) is the fifth most common type of cancers worldwide. However, current therapeutic approaches for this epidemic disease are limited, and its 5-year survival rate hasn't been improved in the past decades. Patient-derived x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b7b908d42b29be14fcd2410f5ae132
https://doi.org/10.18632/oncotarget.6684
https://doi.org/10.18632/oncotarget.6684