Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Chongguang CHEN"'
Publikováno v:
Shipin gongye ke-ji, Vol 44, Iss 23, Pp 253-261 (2023)
In order to investigate the effect of billet-making methods on the volatile components of the Sanhua plum fruit billets, electronic nose and headspace-gas chromatography-ion mobility spectroscopy (HS-GC-IMS) were used to analyze and compare the volat
Externí odkaz:
https://doaj.org/article/7b50a5cba23345edb9c3d9071fc12300
Autor:
Xiangdang Shi, Eva von Weltin, Emma Fitzsimmons, Chau Do, Carolina Caban Rivera, Chongguang Chen, Lee-Yuan Liu-Chen, Ellen M. Unterwald
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Mechanistic target of rapamycin (mTOR) C1 and its downstream effectors have been implicated in synaptic plasticity and memory. Our prior work demonstrated that reactivation of cocaine memory engages a signaling pathway consisting of Akt, glycogen syn
Externí odkaz:
https://doaj.org/article/9ce6582218524563975336a5db5daf95
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Selective kappa opioid receptor (KOR) agonists are promising antipruritic agents and analgesics. However, clinical development of KOR agonists has been limited by side effects, including psychotomimetic effects, dysphoria, and sedation, except for na
Externí odkaz:
https://doaj.org/article/b6b3def666d547b68d79b7c05e40fed6
Autor:
Juliet Mengaziol, Amelia D Dunn, Gregory Salimando, Lisa Wooldridge, Jordi Crues-Muncunill, Darrell Eacret, Chongguang Chen, Kathryn Bland, Lee-Yuan Liu-Chen, Michelle E Ehrlich, Gregory Corder, Julie A Blendy
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0270317 (2022)
Key targets of both the therapeutic and abused properties of opioids are μ-opioid receptors (MORs). Despite years of research investigating the biochemistry and signal transduction pathways associated with MOR activation, we do not fully understand
Externí odkaz:
https://doaj.org/article/466f545ecc3444c2ab07f20e19c44050
Autor:
Andre B. Toussaint, Alexandra S. Ellis, Angela R. Bongiovanni, Drew R. Peterson, Charlotte C. Bavley, Reza Karbalaei, Hannah L. Mayberry, Shivam Bhakta, Carmen C. Dressler, Caesar G. Imperio, John J. Maurer, Heath D. Schmidt, Chongguang Chen, Kathryn Bland, Lee-Yuan Liu-Chen, Mathieu E. Wimmer
BackgroundA growing body of preclinical studies report that preconceptional experiences can have a profound and long-lasting impact on adult offspring behavior and physiology. However, less is known about paternal drug exposure and its effects on rew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::862eb951c96691631e0d2102bb3f6fb5
https://doi.org/10.1101/2023.01.03.522600
https://doi.org/10.1101/2023.01.03.522600
Autor:
Juliet Mengaziol, Amelia D. Dunn, Jordi Crues-Muncunill, Darrell Eacret, Chongguang Chen, Kathryn Bland, Lee-Yuan Liu-Chen, Michelle E. Ehrlich, Julie A. Blendy
Key targets of both the therapeutic and abused properties of opioids are μ-opioid receptors (MORs). Despite years of research investigating the biochemistry and signal transduction pathways associated with MOR activation, we do not fully understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e817aa75b2c76310a8012307b07e801b
https://doi.org/10.1101/2022.06.09.495430
https://doi.org/10.1101/2022.06.09.495430
Autor:
Mengchu Li, Huiqun Wang, Peng Huang, Frederick J. Ehlert, Yan Zhang, Yi-Ting Chiu, Yi Zheng, Chongguang Chen, Danni Cao, Lee-Yuan Liu-Chen
Publikováno v:
ACS Chemical Neuroscience. 11:3036-3050
Nalfurafine, a moderately selective kappa opioid receptor (KOR) agonist, is used in Japan for treatment of itch without causing dysphoria or psychotomimesis. Here we characterized the pharmacology of compound 42B, a 3-dehydroxy analogue of nalfurafin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f0d0a602c9e42a7f9fe3c2d14d2a009
https://doi.org/10.1021/acschemneuro.0c00407
https://doi.org/10.1021/acschemneuro.0c00407
Publikováno v:
Handb Exp Pharmacol
The Kappa Opioid Receptor ISBN: 9783030890735
The Kappa Opioid Receptor ISBN: 9783030890735
This chapter provides a general introduction to the dynorphins (DYNs) / kappa opioid receptor (KOR) system, including DYN peptides, neuroanatomy of the DYNs / KOR system, cellular signaling, and in vivo behavioral effects of KOR activation and inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7538719025eca16394931da47ce4fc8f
https://europepmc.org/articles/PMC9013522/
https://europepmc.org/articles/PMC9013522/
Publikováno v:
Handb Exp Pharmacol
The Kappa Opioid Receptor ISBN: 9783030890735
The Kappa Opioid Receptor ISBN: 9783030890735
We reported previously that GEC1 (glandular epithelial cell 1), a member of microtubule-associated proteins (MAPs), interacted directly with the C-tail of KOR (KCT) and tubulin, and enhanced cell surface expression of KOR in CHO cells by facilitating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a2ea5744312ae308286b7e5233ab3b
https://pubmed.ncbi.nlm.nih.gov/33404775
https://pubmed.ncbi.nlm.nih.gov/33404775
Publikováno v:
The Kappa Opioid Receptor ISBN: 9783030890735
Handb Exp Pharmacol
Handb Exp Pharmacol
Antibodies are important tools for protein and peptide research, including for the kappa opioid receptor (KOR) and dynorphins (Dyns). Well-characterized antibodies are essential for rigorous and reproducible research. However, lack of validation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c455d37dd15c484b9110cda2ac972bdd
https://doi.org/10.1007/164_2021_467
https://doi.org/10.1007/164_2021_467