Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chongcheng Wang"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Anesthetics are essential for cancer surgery, but accumulated research have proven that some anesthetics promote the occurrence of certain cancers, leading to adverse effects in the lives of patients. Although anesthetic technology is mature, there i
Externí odkaz:
https://doaj.org/article/1b8d97b7f0474c46a5af8f17e0bcc4ff
Autor:
Cong Hua, Xuanzhong Wang, Shipeng Liang, Xi chen, Chen Li, Guangqiang You, Chongcheng Wang, Tianfei Luo, Zhenchuan Wang, Pengfei Ge
Publikováno v:
Biochemical and Biophysical Research Communications. 589:1-8
BNIP3 is found to eliminate cancer cells via causing mitochondrial damage and endoplasmic reticulum stress, but it remains elusive of its role in regulating DNA double strand breaks (DSBs). In this study, we find that silibinin triggers DNA DSBs, ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78c37820d8577885935ea20c4cf86e5
https://doi.org/10.1016/j.bbrc.2021.11.110
https://doi.org/10.1016/j.bbrc.2021.11.110
Autor:
Zhen-chuan Wang, Shi-peng Liang, Lei Wang, Xuanzhong Wang, Pengfei Ge, Guangfan Chi, Chuan He, Chongcheng Wang, Tianfei Luo, Chun-sheng Feng, Shan Lu, Chen Li
Publikováno v:
Acta Pharmacologica Sinica
Ferroptotic cell death is characterized by iron-dependent lipid peroxidation that is initiated by ferrous iron and H2O2 via Fenton reaction, in which the role of activating transcription factor 3 (ATF3) remains elusive. Brucine is a weak alkaline ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abf960d7c00f638666b2f8e9c6c6ca7
http://europepmc.org/articles/PMC8463534
http://europepmc.org/articles/PMC8463534
Autor:
Xuanzhong Wang, Meihua Piao, Zhen-chuan Wang, Tianfei Luo, Shi-peng Liang, Guangfan Chi, Shan Lu, Lei Wang, Chongcheng Wang, Pengfei Ge, Chuan He
Publikováno v:
Acta Pharmacologica Sinica
FOXO3a (forkhead box transcription factor 3a) is involved in regulating multiple biological processes in cancer cells. BNIP3 (Bcl-2/adenovirus E1B 19-kDa-interacting protein 3) is a receptor accounting for priming damaged mitochondria for autophagic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11472b4eb18998a63ef952589af571d4
http://europepmc.org/articles/PMC8285492
http://europepmc.org/articles/PMC8285492
Autor:
Meihua Piao, Lei Wang, Yinan Luo, Xuanzhong Wang, Chongcheng Wang, Pengfei Ge, Chuan He, Shan Lu, Guangfan Chi
Publikováno v:
Biochemical and Biophysical Research Communications. 518:590-597
RSL3 is a type of small molecular compound which can inactivate glutathione peroxidase 4 (GPX4) and induce ferroptosis, but its role in glioma cell death remains unclear. In this study, we found RSL3 inhibited the viabilities of glioma cells and indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b316b94cb3ad18d046fd591ad9162c
https://doi.org/10.1016/j.bbrc.2019.08.096
https://doi.org/10.1016/j.bbrc.2019.08.096
Autor:
Xinyu Wang, Guangfan Chi, Shan Lu, Jiayue Cui, Lei Wang, Pengfei Ge, Chuan He, Chongcheng Wang, Xuanzhong Wang, Meihua Piao, Shi-peng Liang
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 8, Pp 1-16 (2020)
Cell Death and Disease, Vol 11, Iss 8, Pp 1-16 (2020)
Induction of lethal autophagy has become a strategy to eliminate glioma cells, but it remains elusive whether autophagy contributes to cell death via causing mitochondria damage and nuclear translocation of apoptosis inducing factor (AIF). In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1691b585af1327528ca8c8d9309643
http://europepmc.org/articles/PMC7429844
http://europepmc.org/articles/PMC7429844
Autor:
Xuanzhong Wang, Lei Wang, Mengxin Li, Shan Lu, Dong Song, Pengfei Ge, Chongcheng Wang, Chuan He, Xinyu Wang
Publikováno v:
Oncology Letters
Erastin is a small molecular compound that induces ferroptosis by binding to voltage-dependent anion-selective channel protein (VDAC)2, VDAC3 and solute carrier family 7 member 5 inhibiting the cystine/glutamate antiporter. However, to the best of ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd5e18a4c6cc299eaeb543e389b66d9
https://doi.org/10.3892/ol.2020.11918
https://doi.org/10.3892/ol.2020.11918
Autor:
Yinan Luo, Pengfei Ge, Chuan He, Chongcheng Wang, Xuanzhong Wang, Shan Lu, Bin Lu, Ye Ding, Guangfan Chi, Zongqi Wang, Meihua Piao
Publikováno v:
Cancer Letters. 425:31-42
RIP1 and RIP3 are necroptosis initiators, but their roles in regulation of glycolysis remain elusive. In this study, we found shikonin activated RIP1 and RIP3 in glioma cells in vitro and in vivo, which was accompanied with glycolysis suppression. Fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abd71ddd2655567e617344bcd30907d
https://doi.org/10.1016/j.canlet.2018.03.046
https://doi.org/10.1016/j.canlet.2018.03.046
Autor:
Yinan Luo, Shan Lu, Ye Ding, Chongcheng Wang, Pengfei Ge, Meihua Piao, Chuan He, Xuanzhong Wang, Ji Zhang, Lei Wang, Guangfan Chi, Ke Sai
Publikováno v:
Cancer letters. 467
Chromatinolysis refers to enzymatic degradation of nuclear DNA and is regarded as one of the crucial events leading to cell death. Mixed-lineage kinase domain-like protein (MLKL) has been identified as a key executor of necroptosis, but it remains un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d903d4ee92217edf83dd2118ccc78f08
https://pubmed.ncbi.nlm.nih.gov/31917020
https://pubmed.ncbi.nlm.nih.gov/31917020
Autor:
Yinan Luo, Ye Ding, Meihua Piao, Ke Sai, Xuanzhong Wang, Shan Lu, Chongcheng Wang, Lei Wang, Guangfan Chi, Ji Zhang, Pengfei Ge, Chuan He
Publikováno v:
Cancer Letters. 472:183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d60addc40a5a1a2f70d66fdf1ec635d
https://doi.org/10.1016/j.canlet.2019.12.035
https://doi.org/10.1016/j.canlet.2019.12.035