Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Chongbo, Zhao"'
Autor:
Sushan Luo, Qilong Jiang, Wenshuang Zeng, Qinzhou Wang, Zhangyu Zou, Yanyan Yu, Daojun Hong, Quantao Zeng, Song Tan, Zhouao Zhang, Yong Zhang, Xiuming Guo, Jing Chen, Zhongyan Zhao, Shixiong Huang, Jianquan Shi, Ying Chen, Lei Du, Chong Yan, Jianying Xi, Jie Song, Chongbo Zhao, the Chinese Myasthenia Gravis Collaborating Group (CMGCG)
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 8, Pp 2212-2221 (2024)
Abstract Objective Efgartigimod, a neonatal Fc receptor antagonist, facilitates antibody degradation including pathogenic IgGs. The ADAPT study demonstrated the tolerability and efficacy of efgartigimod in the treatment of generalized myasthenia grav
Externí odkaz:
https://doaj.org/article/4ed052dcd6e640d5909d6e1483e6906d
Autor:
Jiaojiao Ma, Dan Chen, Fangfang Yi, Jie Song, Sushan Luo, Huahua Zhong, Jianying Xi, Zongtai Wu, Zunbo Li, Chongbo Zhao
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionPatients with myasthenia gravis (MG) display strong treatment heterogeneity. Recent studies have indicated that low-dose steroids or immunosuppressants are effective. However, factors affecting the add-on of non-corticosteroid immunosuppr
Externí odkaz:
https://doaj.org/article/67e20c93e8504bcd97aa1718855d700e
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAs targeted drug development in myasthenia gravis (MG) continues to advance, it is important to compare the efficacy of these drugs for better clinical decision-making. However, due to the varied regimens and dosages used in clinical trials
Externí odkaz:
https://doaj.org/article/f65b93efb9f94c30ab4ffc8a94e6e29f
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Hereditary transthyretin amyloidosis (ATTRv; v for variant) with polyneuropathy is a rare, progressive, and fatal autosomal dominant disorder. Therapies such as liver transplantation and TTR stabilizations have limitations. Patisiran is a
Externí odkaz:
https://doaj.org/article/93b9a386074d48278b67b660f919265b
Autor:
Peijie Zhou, Biao Zhang, Xuan Wang, Jiawei Duan, Jinkai Li, Jie Wang, Ning Xia, Shihao Zhang, Jinghui Wang, Dongyan Guo, Chongbo Zhao, Huanxian Shi, Jiangxue Cheng, Yundong Xie, Jing Sun, Xiaofei Zhang
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 9, Pp 105897- (2024)
Hyperuricemia (HUA), recognized as the fourth “high” condition following hypertension, hyperlipidemia, and hyperglycemia, is a metabolic disorder that severely impairs renal function. Spike lavender essential oil (SLEO) exhibits substantial anti-
Externí odkaz:
https://doaj.org/article/5a641360bec84c8196972b08cbec4cf7
Autor:
Huahua Zhong, Li Zeng, Xuefan Yu, Qing Ke, Jihong Dong, Yan Chen, Lijun Luo, Xueli Chang, Junhong Guo, Yiqi Wang, Hui Xiong, Rongrong Liu, Changxia Liu, Jibao Wu, Jie Lin, Jianying Xi, Wenhua Zhu, Song Tan, Fuchen Liu, Jiahong Lu, Chongbo Zhao, Sushan Luo
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background As the most common subtype of adult muscular dystrophy worldwide, large cohort reports on myotonic dystrophy type I (DM1) in China are still lacking. This study aims to analyze the genetic and clinical characteristics of Chinese H
Externí odkaz:
https://doaj.org/article/43cef6e073334a009d68304f552df021
Autor:
Kexin Jiao, Jialong Zhang, Ningning Wang, Xingyu Gu, Xuechun Chang, Xingyu Xia, Bochen Zhu, Mingshi Gao, Nachuan Cheng, Chongbo Zhao, Jianying Xi, Wenhua Zhu
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103562- (2024)
GlcNAc2-epimerase myopathy is a rare autosomal recessive myopathy characterized by distal involvement in the lower extremities. Our study reprogrammed human-induced pluripotent stem cells from peripheral blood mononuclear cells of a patient with GNE
Externí odkaz:
https://doaj.org/article/72e21426c0fa43a5aca7565c4cfc1090
Autor:
Lian Zhong, Chengxun He, Meiyan Li, Xu Wu, Yan Gou, Zhao Geng, Chengjun He, Chongbo Zhao, Chunjie Wu
Publikováno v:
Journal of Taibah University for Science, Vol 18, Iss 1 (2024)
This paper intended to study the mechanism and active ingredients of ACB anti-epilepsy. The antiepileptic activity of ACB validated in PTZ kindled rats, ACB could increase the seizure latency and reduce seizure duration, attenuate spatial learning an
Externí odkaz:
https://doaj.org/article/2127edcdeb5c4d97bb5bc5592d0b2bc6
Autor:
Jie Song, Xiao Huan, Yuanyi Chen, Yeting Luo, Huahua Zhong, Yuan Wang, Lei Yang, Caihua Xi, Yu Yang, Jianying Xi, Jianming Zheng, Zongtai Wu, Chongbo Zhao, Sushan Luo
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Eculizumab has improved recovery from ventilatory support in myasthenic crisis (MC) cases. However, the safety and efficacy profiles from prospective studies are still lacking. This study aimed to explore eculizumab’s safety and efficacy in a prosp
Externí odkaz:
https://doaj.org/article/3b2104cb0774475ebaf6d823628db8aa
Autor:
Jie Song, Haiyan Wang, Xiao Huan, Qilong Jiang, Zongtai Wu, Chong Yan, Jianying Xi, Chongbo Zhao, Huiyu Feng, Sushan Luo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionEfgartigimod is effective and well-tolerated in patients with anti-acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (MG). However, the therapeutic potential and the safety profile of efgartigimod in myasthenic
Externí odkaz:
https://doaj.org/article/32bd87e8d6494ba7a6f7117366d52b66