Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Chong-Xian Pan"'
Autor:
Thomas M. Steele, Maria Malvina Tsamouri, Salma Siddiqui, Christopher A. Lucchesi, Demitria Vasilatis, Benjamin A. Mooso, Blythe P. Durbin-Johnson, Ai-Hong Ma, Nazila Hejazi, Mamta Parikh, Maria Mudryj, Chong-xian Pan, Paramita M. Ghosh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cisplatin-based combination chemotherapy is the foundation for treatment of advanced bladder cancer (BlCa), but many patients develop chemoresistance mediated by increased Akt and ERK phosphorylation. However, the mechanism by which cisplati
Externí odkaz:
https://doaj.org/article/e7fd4fc41429405c9cbe1caf0f8d8467
Autor:
Weijie Ma, Ruobing Xue, Zheng Zhu, Hizra Farrukh, Wenru Song, Tianhong Li, Lei Zheng, Chong-xian Pan
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-19 (2023)
Abstract Immunotherapy has become the central pillar of cancer therapy. Immune checkpoint inhibitors (ICIs), a major category of tumor immunotherapy, reactivate preexisting anticancer immunity. Initially, ICIs were approved only for advanced and meta
Externí odkaz:
https://doaj.org/article/da7f7c484f764fc5a1c80950a97cc28b
Autor:
Kevin Pan, Hizra Farrukh, Veera Chandra Sekhar Reddy Chittepu, Huihong Xu, Chong-xian Pan, Zheng Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-21 (2022)
Abstract Adoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. However, CAR immunotherapy in sol
Externí odkaz:
https://doaj.org/article/919452a165e941f4aff22bd24ae2f4c5
Autor:
Shaoming Zhu, Tian Zhang, Lei Zheng, Hongtao Liu, Wenru Song, Delong Liu, Zihai Li, Chong-xian Pan
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-33 (2021)
Abstract Immunotherapies such as immune checkpoint blockade (ICB) and adoptive cell therapy (ACT) have revolutionized cancer treatment, especially in patients whose disease was otherwise considered incurable. However, primary and secondary resistance
Externí odkaz:
https://doaj.org/article/b25fc88c0f744c8dbc545b1e014a7433
Autor:
Hasibur Rehman, Darshan S. Chandrashekar, Chakravarthi Balabhadrapatruni, Saroj Nepal, Sai Akshaya Hodigere Balasubramanya, Abigail K. Shelton, Kasey R. Skinner, Ai-Hong Ma, Ting Rao, Sumit Agarwal, Marie-Lisa Eich, Alyncia D. Robinson, Gurudatta Naik, Upender Manne, George J. Netto, C. Ryan Miller, Chong-xian Pan, Guru Sonpavde, Sooryanarayana Varambally, James E. Ferguson III
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Metastatic urothelial carcinoma is generally incurable with current systemic therapies. Chromatin modifiers are frequently mutated in bladder cancer, with ARID1A-inactivating mutations present in about 20% of tumors. EZH2, a histone methyltransferase
Externí odkaz:
https://doaj.org/article/8e79799b8d1942819fca44a09858150e
Autor:
Mamta Parikh, Chengfei Liu, Chun-Yi Wu, Christopher P. Evans, Marc Dall’Era, Daniel Robles, Primo N. Lara, Neeraj Agarwal, Allen C. Gao, Chong-Xian Pan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Niclosamide has preclinical activity against a wide range of cancers. In prostate cancer, it inhibits androgen receptor variant 7 and synergizes with abiraterone. The approved niclosamide formulation has poor oral bioavailability. The primar
Externí odkaz:
https://doaj.org/article/7deaebe005d14169a2841537a9f695b8
Autor:
Demet Candas-Green, Bowen Xie, Jie Huang, Ming Fan, Aijun Wang, Cheikh Menaa, Yanhong Zhang, Lu Zhang, Di Jing, Soheila Azghadi, Weibing Zhou, Lin Liu, Nian Jiang, Tao Li, Tianyi Gao, Colleen Sweeney, Rulong Shen, Tzu-yin Lin, Chong-xian Pan, Omer M. Ozpiskin, Gayle Woloschak, David J. Grdina, Andrew T. Vaughan, Ji Ming Wang, Shuli Xia, Arta M. Monjazeb, William J. Murphy, Lun-Quan Sun, Hong-Wu Chen, Kit S. Lam, Ralph R. Weichselbaum, Jian Jian Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The emergence of tumour adaptive radioresistance can limit the success of radiation therapy and immunotherapy in breast cancer. In this study, the authors demonstrate that CD47 and HER2 are coordinating in tumor response to radiation and that co-bloc
Externí odkaz:
https://doaj.org/article/278b23d810204e89b5b3f18e5d760fef
Autor:
Guru Sonpavde, Na Li, Zheng Zhu, Fan Cheng, Shaoming Zhu, A-Hong Ma, Elio Adib, Ting Rao, Kaiyuan Ni, Veera Chandra Sekhar Reddy Chittepu, Rao Prabhala, Juan Garisto Risco, David Kwiatkowski, Kent Mouw, Chong-xian Pan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/934d422d19464781b6e424dfea9fbd98
Autor:
Giovanni E. Cacciamani, Afsaneh Barzi, Michael B. Eppler, Primo N. Lara, Chong-Xian Pan, Sumeet K. Bhanvadia, Parkash Gill, Monish Aron, Inderbir Gill, Sarmad Sadeghi
Publikováno v:
Cancers, Vol 14, Iss 23, p 5984 (2022)
The role of surgical experience and its impact on the survival requires further investigation. A cohort of patients undergoing radical cystectomy or anterior pelvic exenteration for localized bladder cancer between 2006 and 2013 at 1143 facilities ac
Externí odkaz:
https://doaj.org/article/995a92639fb8428aa2a2e262f4460670
Autor:
Bin Xue, Jiaqi Xu, Wenru Song, Zhimin Yang, Ke Liu, Zihai Li, Lieping Chen, Edward B. Garon, Siwen Hu-Lieskovan, Wei Ding, Chong-Xian Pan, Weijing Sun, Yong-Jun Liu, Lei Zheng, Delong Liu, Michel Sadelain, Cassian Yee, Rongfu Wang, Meixia Chen, Yao Wang, Zhiqiang Wu, Hanren Dai, Can Luo, Yang Liu, Chuan Tong, Yelei Guo, Qingming Yang, Weidong Han, Lisa H. Butterfield, Timothy A. Chan, Ruirong Yuan, Bo Lu, Max Ning, Harald Enzmann, Heinz Zwierzina
Publikováno v:
Journal of Hematology & Oncology, Vol 9, Iss S1, Pp 1-8 (2016)
Table of contents A1 Proceedings of 2016 China Cancer Immunotherapy Workshop, Beijing, China Bin Xue, Jiaqi Xu, Wenru Song, Zhimin Yang, Ke Liu, Zihai Li A2 Set the stage: fundamental immunology in forty minutes Zihai Li A3 What have we learnt from t
Externí odkaz:
https://doaj.org/article/35988a5897e24bc28a19248cd26c053a