Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chong-Ok Lee"'
Cytotoxic cytochalasins from the endozoic fungus Phoma sp. of the giant jellyfish Nemopilema nomurai
Autor:
Eun La Kim, Jian Lin Li, Hung The Dang, Jongki Hong, Chong-Ok Lee, Dong-Kyoo Kim, Won Duk Yoon, Euikyung Kim, Yonghong Liu, Jee H. Jung
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3126-3129
Four new cytochalasin derivatives (1-4), together with cytochalasin B (5), were isolated from the fungus Phoma sp. obtained from the giant jellyfish Nemopilema nomurai. The planar structure and relative stereo-chemistry were established by analysis o
Publikováno v:
Archives of Pharmacal Research. 28:285-289
Two new sulfated saponins designated as certonardosides P2 and I3 (1 and 2) were isolated from the brine shrimp active fraction of the MeOH extract of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral ana
Autor:
Jee H. Jung, Jongki Hong, Weihong Wang, Song-Ja Bae, Kwang Sik Im, Chong-Ok Lee, Hyo-Jin Jang
Publikováno v:
Journal of Natural Products. 67:1654-1660
Twelve new (1-7, 9-13) polyhydroxysterols and two new saponins (14 and 15) were isolated from the starfish Certonardoa semiregularis by activity-guided fractionation. Compounds 1-7 are rare examples of 15-keto steroids from starfish. The side chain o
Autor:
Jee H. Jung, Jongki Hong, Famei Li, Sook Shin, Kwang Sik Im, Weihong Wang, Yujin Park, Chong-Ok Lee, Jae Yang Kong
Publikováno v:
Journal of Natural Products. 66:384-391
Thirteen new polyhydroxysterols (1-5, 7-12, 14, 15) and two known polyhydroxysterols (6, 13) were isolated from the brine shrimp active fraction of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral analys
Publikováno v:
Chemical and Pharmaceutical Bulletin. 51:435-439
Four new saponins, designated as certonardosides K-N (1-3, 5), were isolated, along with culcitoside C(6) (4), from the brine shrimp active fraction of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral an
Publikováno v:
Chemical and Pharmaceutical Bulletin. 55:459-461
A new butenolide (1) was isolated, along with a known acyclic polyhalogenated monoterpene (2), from the brittle star Ophiomastix mixta. The structures were defined by analysis and comparision of the spectral data with those in the literature. The 2,3
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:41-46
To investigate the structure-activity relationship of 7,8-dimethoxy-2-methyl-3-(4,5-methylenedioxy-2-vinylphenyl)isoquinolin-1(2 H )-one 2 , diverse substituted 3-arylisoquinolines were synthesized and tested in vitro antitumor activity against five
Autor:
Yang Ha Cho, Ok-Sang Jung, Chong Ok Lee, Hyonggee Baek, Youn Soo Sohn, Yun Soo Kim, Young-A Lee
Publikováno v:
International Journal of Pharmaceutics. 153:79-91
A novel class of water-soluble polyphosphazene-(diamine)platinum(II) conjugate drugs [N=P(S)Am·PtA 2 )] n have been designed and synthesized by incorporating the antitumor (diamine)platinum(II) moiety (A 2 Pt 2+ ) to a polyphosphazene back-bone alon
Publikováno v:
Journal of Natural Products. 64:533-535
A known (1) and four new (2--5) lyso-PAF (platelet activating factor) derivatives were isolated from the sponge Spirastrella abata. Two of them are unprecedented in having a methoxy group at C-2'. The structures have been determined by combined spect
Publikováno v:
ChemInform. 29
To investigate the structure-activity relationship of 7,8-dimethoxy-2-methyl-3-(4,5-methylenedioxy-2-vinylphenyl)isoquinolin-1(2 H )-one 2 , diverse substituted 3-arylisoquinolines were synthesized and tested in vitro antitumor activity against five