Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Chong Yew, Tan"'
Autor:
Chong Yew Tan, Samuel Virtue, Guillaume Bidault, Martin Dale, Rachel Hagen, Julian L. Griffin, Antonio Vidal-Puig
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2039-2047 (2015)
Although many transcriptional pathways regulating BAT have been identified, the role of lipid biosynthetic enzymes in thermogenesis has been less investigated. Whereas cold exposure causes changes in the fatty acid composition of BAT, the functional
Externí odkaz:
https://doaj.org/article/a51ca65fe0f1425f9e7818c04e6739a3
Autor:
Adam T. Townson, Yogeshkumar Malam, Katy Surman, Shaan Chhabra, Chong Yew Tan, Patrick Deegan, John Mathews
Publikováno v:
Journal of clinical lipidology. 16(2)
Mesenteric panniculitis is a rare disease caused by idiopathic inflammation of adipose tissue, most commonly affecting the mesentery of the small bowel. We present a unique case of mesenteric panniculitis in a patient with Tangier disease; a rare gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a747dcd7121d00202aa41c07321ccf1
https://pubmed.ncbi.nlm.nih.gov/34975012
https://pubmed.ncbi.nlm.nih.gov/34975012
Autor:
Simona D'Amore, Kathleen Page, Aimée Donald, Khadijeh Taiyari, Brian Tom, Patrick Brian Deegan, Chong Yew Tan, Kenneth Poole, Simon Allan Jones, Atul Mehta, Derralynn Hughes, Reena Sharma, Robin Henry Lachmann, Aunpam Chakrapani, Tarekegn Geberhiwot, Saikat Santra, Timothy Martin Cox
Background The Gaucher Investigative Therapy Evaluation (GAUCHERITE) is a national clinical cohort of 250 patients aged 5–87 years with Gaucher disease - an ultra-rare genetic disorder. To inform clinical decision-making and improve pathophysiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50a04e14b992758eb52e22b6b7f140c
https://doi.org/10.21203/rs.3.rs-543669/v1
https://doi.org/10.21203/rs.3.rs-543669/v1
Autor:
Stella Mazurová, John W. Day, Mazen M. Dimachkie, Sónia Tizon, Anna Kostera-Pruszczyk, Tahseen Mozaffar, Joel Charrow, Chafic Karam, Ricardo Maré, Jean-Baptiste Noury, Dewi Guellec, Jorge Alonso-Pérez, Acary Souza Bulle Oliveira, Loren D M Pena, Tianyue Zhou, Sergey Illarioshkin, Nathan Thibault, Marcelo Rugiero, Can Ebru Bekircan-Kurt, Lauren Chase, Monica Sciacco, Mamatha Pasnoor, Jenny Billy, Mark Tarnopolsky, Fabien Zagnoli, Marie Wencel, Sevim Erdem-Ozdamar, Erin Hatcher, Madoka Mori, Céline Tard, Nicolas Mavroudakis, Emmanuelle Salort-Campana, Antonio Toscano, Shafeeq Ladha, Angela Genge, Ans T. van der Ploeg, Michela Guglieri, Judith Johnson, Fanny Duval, Loïc Danjoux, Christopher Hug, Robert D. Henderson, Robert Neel, Luca Solera, Aleksandra Nadaj-Pakleza, Silvia Boschi, Nizar Chahin, Maurizio Gualtiero Moggio, Peter Young, Priya S. Kishnani, Yin-Hsiu Chien, Alexandra Kautzky-Willer, Claire Questienne, Francoise Bouhour, Gabriela A Niizawa, Ekaterina Fedotova, Tiziana Enrica Mongini, Harmke A. van Kooten, Vera Malinova, Sina Helms, Shahram Attarian, Patrick Deegan, Guilhem Sole, Hamilton Cirne, Ludwig Gutmann, Kenneth I. Berger, Laura Carrera Garcia, N A M E van der Beek, Stephanie Dearmey, Suzara Souto Lopes, Anna Potulska-Chromik, Joao Lindolfo Borges, Yesim Parman, Michaela Riedl, Sergey A. Klyushnikov, Olivier Huynh-Ba, Gauthier Remiche, Paula R. Clemens, Andrea Swenson, Stephan Wenninger, Miriam Hufgard-Leitner, Eugen Mengel, Kristina An Haack, Eve Gandolfo, David Reyes-Leiva, Jean-Baptiste Davion, Chester Whitley, Young Chul Choi, Patricia Altemus, Maria Judit Molnar, Perry B. Shieh, Matthias Vorgerd, Julia B Hennermann, Cheryl Smith, Volker Straub, Lauren Noll, Pascal Laforet, Andres Nascimento Osorio, Clarisa Maxit, Anne-Catherine Aubé-Nathier, Ozlem Goker-Alpan, Olimpia Musumeci, Louisa Müller-Miny, Tarekegn Hiwot, Jacqui Langton, Christopher Nance, Daniel Natera-de Benito, Jeffrey Statland, Nicola Longo, Vivien Pautot, Zoltan Grosz, Thomas Stulnig, Matthias Boentert, Anne-Katrin Guettsches, Chong Yew Tan, Erik Ortega, Derralynn Hughes, Hacer Durmus Tekce, Mark Roberts, Lenka Linková, Amel Karaa, Hani Kushlaf, Anthony Behin, Margarida Ramos Lopes, Jordi Diaz-Manera, Alessia Pugliese, Paulo Victor Sgobbi Souza, Carrie Bailey, Jennifer B Avelar, Hirofumi Komaki, Frederic Taithe, Benedikt Schoser, Sabine Specht, Kathryn E Brown, Gerson Carvalho
Publikováno v:
The Lancet Neurology, 20(12), 1012-1026. Lancet Publishing Group
Summary Background Pompe disease is a rare, progressive neuromuscular disorder caused by deficiency of acid α-glucosidase (GAA) and accumulation of lysosomal glycogen. We assessed the safety and efficacy of avalglucosidase alfa, a recombinant human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070f1f6f1e025674e4ced58aa9218fbf
http://hdl.handle.net/11570/3218654
http://hdl.handle.net/11570/3218654
Autor:
Martin Gorges, Duncan Cole, Chong Yew Tan, Reena Sharma, Anupam Chakrapani, Stanislav Bardins, Aimee Donald, Simon Allan Jones, D Hughes, Erich Schneider
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-12 (2020)
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-12 (2020)
Background Neurological forms of Gaucher disease, the inherited disorder of β-Glucosylceramidase caused by bi-allelic variants in GBA1, is a progressive disorder which lacks a disease-modifying therapy. Systemic manifestations of disease are effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07571123ec4e518049371f023dbd9304
https://doi.org/10.21203/rs.3.rs-37355/v1
https://doi.org/10.21203/rs.3.rs-37355/v1
Autor:
Sam Virtue, Mojgan Masoodi, Vidya Velagapudi, Chong Yew Tan, Martin Dale, Tapani Suorti, Marc Slawik, Margaret Blount, Keith Burling, Mark Campbell, Naomi Eguchi, Gema Medina-Gomez, Jaswinder K Sethi, Matej Orešič, Yoshihiro Urade, Julian L Griffin, Antonio Vidal-Puig
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39512 (2012)
Mice lacking Peroxisome Proliferator-Activated Receptor γ2 (PPARγ2) have unexpectedly normal glucose tolerance and mild insulin resistance. Mice lacking PPARγ2 were found to have elevated levels of Lipocalin prostaglandin D synthase (L-PGDS) expre
Externí odkaz:
https://doaj.org/article/83f9f43fca3648e98c8d3edfefa64bdf
Autor:
Kirsi H Pietiläinen, Tomasz Róg, Tuulikki Seppänen-Laakso, Sam Virtue, Peddinti Gopalacharyulu, Jing Tang, Sergio Rodriguez-Cuenca, Arkadiusz Maciejewski, Jussi Naukkarinen, Anna-Liisa Ruskeepää, Perttu S Niemelä, Laxman Yetukuri, Chong Yew Tan, Vidya Velagapudi, Sandra Castillo, Heli Nygren, Tuulia Hyötyläinen, Aila Rissanen, Jaakko Kaprio, Hannele Yki-Järvinen, Ilpo Vattulainen, Antonio Vidal-Puig, Matej Orešič
Publikováno v:
PLoS Biology, Vol 9, Iss 6, p e1000623 (2011)
Identification of early mechanisms that may lead from obesity towards complications such as metabolic syndrome is of great interest. Here we performed lipidomic analyses of adipose tissue in twin pairs discordant for obesity but still metabolically c
Externí odkaz:
https://doaj.org/article/fcf716f0b0514305ae1327d2d91cb67b
Autor:
Karen Tylee, Chong Yew Tan, Karolina M. Stepien, Heather J. Church, Christian J. Hendriksz, Andrew Oldham
Publikováno v:
Molecular Genetics and Metabolism. 129:S120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af61c492f99e872f4efa9d3e1dfe480
https://doi.org/10.1016/j.ymgme.2019.11.311
https://doi.org/10.1016/j.ymgme.2019.11.311
Autor:
Hubert Vidal, Tingting Wu, Jaswinder K. Sethi, Martine Laville, Gema Medina-Gómez, Francisco J. Tinahones, Chong Yew Tan, Mikael Bjursell, Miguel López, Rachel M. Hagen, Antoinette Tuthill, Christopher J. Lelliott, Antonio Vidal-Puig, Helen J. Atherton, Julian L. Griffin, Audrey Sicard, Etienne Lefai, Matej Orešič, Mohammad Bohlooly-Y, Robert V. Considine, Sam Virtue, José Manuel Fernández-Real, Stefania Carobbio, Dominique Langin, Nuria Barbarroja, Marc Slawik
Publikováno v:
Diabetes
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Diabetes, 2013, 62 (11), pp.3697-3708. ⟨10.2337/db12-1748⟩
Diabetes, American Diabetes Association, 2013, 62 (11), pp.3697-3708. ⟨10.2337/db12-1748⟩
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Diabetes, 2013, 62 (11), pp.3697-3708. ⟨10.2337/db12-1748⟩
Diabetes, American Diabetes Association, 2013, 62 (11), pp.3697-3708. ⟨10.2337/db12-1748⟩
The epidemic of obesity imposes unprecedented challenges on human adipose tissue (WAT) storage capacity that may benefit from adaptive mechanisms to maintain adipocyte functionality. Here, we demonstrate that changes in the regulatory feedback set po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1b1c4a967559f56361109a5510ce68
http://europepmc.org/articles/PMC3806615
http://europepmc.org/articles/PMC3806615
Autor:
Chong Yew Tan, Jeffrey K. Huang, Christopher J. Lelliott, Alberto Camacho, Antonio Vidal-Puig, Ilse Delint-Ramirez, Robin J.M. Franklin, Maria Fuller
Publikováno v:
European Journal of Neuroscience. 38:2672-2683
Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha (PGC1a) is involved in energy and lipid metabolism, and its loss leads to neurodegenerative changes in the striatum. Here we performed lipidomic analysis on brain extracts from PGC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8d23138c2009d272fba352f41d0101
https://doi.org/10.1111/ejn.12281
https://doi.org/10.1111/ejn.12281