Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chong Wai Tong"'
Publikováno v:
Experimental Neurology. 199:499-512
Toxin-induced animal models of Parkinson's disease (PD) exhibit many of the same neuroinflammatory changes seen in patients suggesting a role for inflammation in DA neuron loss. Yet, despite this inflammation, the progressive loss of DA neurons that
Publikováno v:
Journal of Neural Transmission. 112:601-612
Inflammatory processes are thought to underlie the dopamine (DA) neuron loss seen in Parkinson's disease (PD). However, it is not known if the inflammation precedes that loss, or is a consequence of it. We injected tumor necrosis factor alpha (TNFalp
Publikováno v:
Neuroscience. 124:619-628
We previously reported that injection of the Gram (-) bacteriotoxin, lipopolysaccharide (LPS), into gravid females at embryonic day 10.5 led to the birth of animals with fewer than normal dopamine (DA) neurons when assessed at postnatal days (P) 10 a
Autor:
Dave A. Gayle, Paul M. Carvey, Shang Yong Ma, Chong Wai Tong, Jack W. Lipton, Jau-Shyong Hong, ZaoDung D. Ling
Publikováno v:
Movement Disorders. 17:116-124
We investigated whether in utero exposure to the Gram(-) bacteriotoxin lipopolysaccharide (LPS) induces dopamine (DA) neuron loss in rats. The proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) kills DA neurons and is elevated in the br
Autor:
S. Y. Ma, Paul M. Carvey, Toan Q. Vu, Jack W. Lipton, Heather C. Robie, Zaodung Ling, E. Y. Chen, Chong Wai Tong
Publikováno v:
Journal of Neural Transmission. 107:159-176
The D3 preferring dopamine agonist pramipexole has been shown to attenuate the cell loss induced by levodopa in vitro. Pramipexole was herein evaluated in the 6-hydroxydopamine lesion model to determine its in vivo effect. Rats were treated with pram
Publikováno v:
Brain Research. 791:137-145
We previously demonstrated that media conditioned by exposure to ventral mesencephalic (VM) cultures in the presence of pramipexole (PPX) and other drugs with dopamine (DA) D3 properties, increased the growth and survival of DA neurons in recipient V
Publikováno v:
Experimental neurology. 216(2)
We previously demonstrated that in utero exposure to the bacteriotoxin lipopolysaccharide (LPS) led to the birth of rat pups with fewer than normal dopamine (DA) neurons. These animals exhibited significant neuroinflammation in the nigrostriatal path
Autor:
ZaoDung, Ling, Dave A, Gayle, Shang Yong, Ma, Jack W, Lipton, Chong Wai, Tong, Jau-Shyong, Hong, Paul M, Carvey
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 17(1)
We investigated whether in utero exposure to the Gram(-) bacteriotoxin lipopolysaccharide (LPS) induces dopamine (DA) neuron loss in rats. The proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) kills DA neurons and is elevated in the br