Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chong Wai, Tong"'
Publikováno v:
Experimental Neurology. 199:499-512
Toxin-induced animal models of Parkinson's disease (PD) exhibit many of the same neuroinflammatory changes seen in patients suggesting a role for inflammation in DA neuron loss. Yet, despite this inflammation, the progressive loss of DA neurons that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c5fa75d0e8885d47b7ae9520a991e1
https://doi.org/10.1016/j.expneurol.2006.01.010
https://doi.org/10.1016/j.expneurol.2006.01.010
Publikováno v:
Journal of Neural Transmission. 112:601-612
Inflammatory processes are thought to underlie the dopamine (DA) neuron loss seen in Parkinson's disease (PD). However, it is not known if the inflammation precedes that loss, or is a consequence of it. We injected tumor necrosis factor alpha (TNFalp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60364902fdc371d8431580d9560fcbd1
https://doi.org/10.1007/s00702-004-0222-z
https://doi.org/10.1007/s00702-004-0222-z
Publikováno v:
Neuroscience. 124:619-628
We previously reported that injection of the Gram (-) bacteriotoxin, lipopolysaccharide (LPS), into gravid females at embryonic day 10.5 led to the birth of animals with fewer than normal dopamine (DA) neurons when assessed at postnatal days (P) 10 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43d4094a5dc5e1d95a28ce8f6ab0eea
https://doi.org/10.1016/j.neuroscience.2003.12.017
https://doi.org/10.1016/j.neuroscience.2003.12.017
Autor:
Dave A. Gayle, Paul M. Carvey, Shang Yong Ma, Chong Wai Tong, Jack W. Lipton, Jau-Shyong Hong, ZaoDung D. Ling
Publikováno v:
Movement Disorders. 17:116-124
We investigated whether in utero exposure to the Gram(-) bacteriotoxin lipopolysaccharide (LPS) induces dopamine (DA) neuron loss in rats. The proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) kills DA neurons and is elevated in the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83513b475549e710854a7b678ee45a89
https://doi.org/10.1002/mds.10078
https://doi.org/10.1002/mds.10078
Autor:
S. Y. Ma, Paul M. Carvey, Toan Q. Vu, Jack W. Lipton, Heather C. Robie, Zaodung Ling, E. Y. Chen, Chong Wai Tong
Publikováno v:
Journal of Neural Transmission. 107:159-176
The D3 preferring dopamine agonist pramipexole has been shown to attenuate the cell loss induced by levodopa in vitro. Pramipexole was herein evaluated in the 6-hydroxydopamine lesion model to determine its in vivo effect. Rats were treated with pram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33682ad50e3a2145e708064d7edd1dde
https://doi.org/10.1007/s007020050014
https://doi.org/10.1007/s007020050014
Publikováno v:
Brain Research. 791:137-145
We previously demonstrated that media conditioned by exposure to ventral mesencephalic (VM) cultures in the presence of pramipexole (PPX) and other drugs with dopamine (DA) D3 properties, increased the growth and survival of DA neurons in recipient V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d7a6725ff56e457d904066e4987715
https://doi.org/10.1016/s0006-8993(98)00088-2
https://doi.org/10.1016/s0006-8993(98)00088-2
Publikováno v:
Experimental neurology. 216(2)
We previously demonstrated that in utero exposure to the bacteriotoxin lipopolysaccharide (LPS) led to the birth of rat pups with fewer than normal dopamine (DA) neurons. These animals exhibited significant neuroinflammation in the nigrostriatal path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10b581ab58306dac81a156f531cd9cd
https://pubmed.ncbi.nlm.nih.gov/19133261
https://pubmed.ncbi.nlm.nih.gov/19133261
Autor:
ZaoDung, Ling, Dave A, Gayle, Shang Yong, Ma, Jack W, Lipton, Chong Wai, Tong, Jau-Shyong, Hong, Paul M, Carvey
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 17(1)
We investigated whether in utero exposure to the Gram(-) bacteriotoxin lipopolysaccharide (LPS) induces dopamine (DA) neuron loss in rats. The proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) kills DA neurons and is elevated in the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::870e40c38a8e29dbb902eb4cc1651d7f
https://pubmed.ncbi.nlm.nih.gov/11835448
https://pubmed.ncbi.nlm.nih.gov/11835448