A Single Amino Acid Substitution in Structural Protein VP2 Abrogates the Neurotropism of Enterovirus A-71 in Mice.

Autor: Yeo H; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Chong CWH; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Chen EW; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Lim ZQ; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Ng QY; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Yan B; Department of Laboratory Medicine, Molecular Diagnosis Centre, National University Health System, Singapore, Singapore., Chu JJH; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore., Chow VTK; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Alonso S; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2022 Mar 17; Vol. 13, pp. 821976. Date of Electronic Publication: 2022 Mar 17 (Print Publication: 2022).