Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Chondroblast differentiation"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background Osteoarthritis is a chronic disease mainly involving the damage of articular cartilage and the whole articular tissue, which is the main cause of disability in the elderly. To explore more effective treatment measures, this study
Externí odkaz:
https://doaj.org/article/211e9c8653534150af80c0b017bcccd3
Akademický článek
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Autor:
Neil A. Segal, Michael A. Bowes, Yoshinari Kumagai, Alan Brett, Meghan Miller, David M. Rosen, Dawn Mcguire
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-9 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-9 (2021)
Background TPX-100, a promotor of osteoblast and chondroblast differentiation, is a potential osteoarthritis (OA) therapy. This retrospective study compared MRI 3D femoral bone shape changes (B-scores) after intra-articular TPX-100 or placebo and ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7d76e47c8bbcc5f14fa6ef1b62452d
http://europepmc.org/articles/PMC8447757
http://europepmc.org/articles/PMC8447757
Publikováno v:
International Journal of Biological Sciences
Peroxisome proliferator-activated receptor beta/delta (PPARD) is an important determinant of multiple biological processes. Our previous studies identified a missense mutation in the PPARD gene that significantly reduces its transcription activity, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b937e778c52632d01c0c58d3951b9702
https://doi.org/10.7150/ijbs.19714
https://doi.org/10.7150/ijbs.19714
Publikováno v:
Cell Biology International. 39:657-665
This study employed transforming growth factor beta 3 (TGF-β3) induction of the C3H10T1/2 mesenchymal stem cell (MSC) line to construct an in vitro chondrogenic differentiation model for MSCs. A C3H10T1/2 MSC cell line was cultured, amplified, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5cf84048c64ab00090f9bb733230444
https://doi.org/10.1002/cbin.10436
https://doi.org/10.1002/cbin.10436
Autor:
Behrang Alani, Mojtaba Kianmehr, Javad Verdi, Mahdi Noureddini, Rana Moradian Tehrani, Rasoul Salehi, Amirhossein Sahebkar, Hamed Mirzaei
Publikováno v:
Journal of cellular physiology. 233(10)
Human adipose tissue has been identified as a viable alternative source for mesenchymal stem cells. SADSCs were isolated from human scalp biopsy and then were characterized by Flow cytometry. SADSCS expressed CD90, CD44, and CD105 but did not express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68bfb0fcc71a8f8c700baccd95236f1b
https://pubmed.ncbi.nlm.nih.gov/29323717
https://pubmed.ncbi.nlm.nih.gov/29323717
Publikováno v:
Hirurgiâ pozvonočnika. :89-98
Objective. Analysis of morphological criteria of formation of secondary growth plate and vertebral body torsion in scoliosis. Material and Methods. Specimens of vertebral body growth plates from convex and concave sides of deformity, intervertebral d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7a66396980bf62bc760f98408c4ef95
https://doi.org/10.14531/ss2011.3.89-98
https://doi.org/10.14531/ss2011.3.89-98
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 39:857-862
Osteosarcomas and chondrosarcomas are the most common primary bone sarcomas. They are often highly aggressive neoplasms that rapidly progress and eventually recur and give distant metastases. Although the prognosis and quality of life have been impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d0e103544090728fc2ba9905d17fe5
https://doi.org/10.1016/j.biocel.2006.12.003
https://doi.org/10.1016/j.biocel.2006.12.003
Autor:
Tingjiao Liu, Kazuhisa Bessho, Tomoo Tsukazaki, Keizo Furukawa, Toshihisa Komori, Yasuaki Shibata, Akira Yamaguchi, Yu-hao Gao, Kei Sakamoto, Tokutaro Minamizato
Publikováno v:
Journal of Cellular Physiology. 211:728-735
To investigate the molecular mechanism underlying the differentiation of osteoblasts and chondroblasts, we established a clonal cell lines, RD-C6, from Runx2-deficient mouse embryos. RD-C6 cells expressed almost undetectable levels of phenotypes rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078044bc1269dfbd7cfbddc8906892be
https://doi.org/10.1002/jcp.20988
https://doi.org/10.1002/jcp.20988
Autor:
Ramon Bartrons, R. Fernández-Lloris, Owen A. Vaughan, Ronald T. Hay, Francesc Ventura, Nelson Osses, D. Girwood, Ellis Jaffray, Jose Luis Rosa, Linnan Shen
Publikováno v:
FEBS Letters. 580:1215-1221
SOX6 plays key functions in several developmental processes, including neurogenesis and skeleton formation. In this report, we show that SOX6 is modified in vitro and in vivo by small ubiquitin-related modifier (SUMO) on two distinct sites. Mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d83f22d2d476cf291142b5bbc1febf2
https://doi.org/10.1016/j.febslet.2006.01.031
https://doi.org/10.1016/j.febslet.2006.01.031