Inhibition of Mycobacterium tuberculosis InhA by 3‐nitropropanoic acid

Autor: Potjanee Srimanote, Pornpan Pungpo, Bongkochawan Pakamwong, Auradee Punkvang, Prasat Kittakoop, James Spencer, Khomson Suttisintong, Chayanin Hanwarinroj, Pharit Kamsri, Nitima Suttipanta, Sanya Sureram, Chomphunuch Songsiriritthigul

Publikováno v: Songsiriritthigul, C, Hanwarinroj, C, Pakamwong, B, Srimanote, P, Suttipanta, N, Sureram, S, Suttisintong, K, Kamsri, P, Punkvang, A, Spencer, J, Kittakoop, P & Pungpo, P 2021, ' Inhibition of Mycobacterium tuberculosis InhA by 3-nitropropanoic acid ', Proteins: Structure, Function, and Bioinformatics, vol. 90, no. 3, pp. 898-904 . https://doi.org/10.1002/prot.26268

3-Nitropropanoic acid (3NP), a bioactive fungal natural product, was previously demonstrated to inhibit growth of Mycobacterium tuberculosis. Here we demonstrate that 3NP inhibits the 2-trans-enoyl-acyl carrier protein reductase (InhA) from Mycobacte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c24e98a2e8fe260ed2b6c3dc00f235f
https://doi.org/10.1002/prot.26268

Enzymatic electrochemical biosensor for glyphosate detection based on acid phosphatase inhibition

Autor: Gamolwan Tumcharern, Preeyanut Butmee, Margaret Kerr, Marie-José Durand, Anchalee Samphao, Kurt Kalcher, Gérald Thouand, Chomphunuch Songsiriritthigul

Publikováno v: Analytical and Bioanalytical Chemistry. 413:5859-5869

A novel enzymatic electrochemical biosensor was fabricated for the indirect detection of glyphosate-based acid phosphatase inhibition. The biosensor was constructed on a screen-printed carbon electrode modified with silver nanoparticles, decorated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd3e09ac96566b2f46304b59dc344b5
https://doi.org/10.1007/s00216-021-03567-2

Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography

Autor: Pitak Santanirand, Nitima Suttipanta, Siriluk Rattanabunyong, Poonpilas Hongmanee, Patchreenart Saparpakorn, Pornpan Pungpo, Thimpika Pornprom, Adrian J. Mulholland, Supaporn Seetaha, Khomson Suttisintong, Potjanee Srimanote, Kampanart Chayajarus, Rosemary A. Blood, Naruedon Phusi, Zhaoqiang Chen, Sanya Sureram, Pharit Kamsri, Supa Hannongbua, Philip Hinchliffe, Prasat Kittakoop, Kiattawee Choowongkomon, James Spencer, Yuiko Takebayashi, Chomphunuch Songsiriritthigul, Chayanin Hanwarinroj, Weiliang Zhu, Auradee Punkvang

Publikováno v: Kamsri, P, Hanwarinroj, C, Phusi, N, Pornprom, T, Chayajarus, K, Punkvang, A, Suttipanta, N, Srimanote, P, Suttisintong, K, Songsiriritthigul, C, Saparpakorn, P, Hannongbua, S, Rattanabunyong, S, Seetaha, S, Choowongkomon, K, Sureram, S, Kittakoop, P, Hongmanee, P, Santanirand, P, Chen, Z, Zhu, W, Blood, R A, Takebayashi, Y, Hinchliffe, P, Mulholland, A J, Spencer, J & Pungpo, P 2020, ' Discovery of New and Potent InhA Inhibitors as Anti-tuberculosis Agents : Structure Based Virtual Screening Validated by Biological Assays and X-ray Crystallography ', Journal of Chemical Information and Modeling, vol. 60 (2020), no. 1, pp. 226-234 . https://doi.org/10.1021/acs.jcim.9b00918

The enoyl-acyl carrier protein reductase InhA of Mycobacterium tuberculosis is an attractive, validated target for antituberculosis drug development. Moreover, direct inhibitors of InhA remain effective against InhA variants with mutations associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0845f81359c09a90edda6f542008b2fb
https://doi.org/10.1021/acs.jcim.9b00918

A Single Mutation in the Carbohydrate-Binding Module Enhances Cellulase Activity in Bacillus Amyloliquefaciens Mutant

Autor: Somboon Anuntalabhochai, Wasana Suyotha, Sugunya Suebsan, Chomphunuch Songsiriritthigul, K. Sangwijit, Nitipol Polsa

Publikováno v: Walailak Journal of Science and Technology (WJST). 18

From our earlier work, we modified the carbohydrate-binding module (CBM) of Bacillus amyloliquefaciens to increase cellulase activity using cold plasma technology. The cellulase gene (BglC-M) from the mutant was expressed in Escherichia coli BL21(DE3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f8cbcf5783aeb722f7db7cced2f2356
https://doi.org/10.48048/wjst.2021.23985

Investigation of solvated calcium dication structure in pure water, methanol, and ethanol solutions by means of K and L2,3-edges X-ray absorption spectroscopy

Autor: Nobuhiro Kosugi, T. Saisopa, Denis Céolin, Chatree Saiyasombat, Chomphunuch Songsiriritthigul, Wandared Pokapanich, Saowanaporn Tangsukworakhun, Prayoon Songsiriritthigul, Hayato Yuzawa, Yuttakarn Rattanachai, Kanchanasuda Klaiphet

Publikováno v: Journal of Electron Spectroscopy and Related Phenomena
Journal of Electron Spectroscopy and Related Phenomena, Elsevier, 2020, 244, pp.146984-. ⟨10.1016/j.elspec.2020.146984⟩

The interaction of an ion with surrounding solvent molecules is revealed by X-ray absorption spectroscopy in transmission mode for the case of calcium dication dissolved in pure water, methanol and ethanol at the Ca K and L2,3-edges. The near-thresho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d687a7669a9c77a4f7cd5c9db45d2e5
https://hal.archives-ouvertes.fr/hal-03492055