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pro vyhledávání: '"Choline transport"'
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Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 250-257 (2022)
FEBS Open Bio
FEBS Open Bio
Acetylcholine (ACh), an excitatory neurotransmitter, is biosynthesized from choline in cholinergic neurons. Import from the extracellular space to the intracellular environment through the high‐affinity choline transporter is currently regarded to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8196d5134fc88cb820400726c30a1c97
https://doaj.org/article/071dbb74268b4326ad0804956b29d31f
https://doaj.org/article/071dbb74268b4326ad0804956b29d31f
Autor:
Tafere Mulaw Belete
Publikováno v:
Drug Design, Development and Therapy. 14:3875-3889
Malaria is a major global health problem that causes significant mortality and morbidity annually. The therapeutic options are scarce and massively challenged by the emergence of resistant parasite strains, which causes a major obstacle to malaria co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef9e1dc3c580d5eb48a0c7eb92195db
https://doi.org/10.2147/dddt.s265602
https://doi.org/10.2147/dddt.s265602
Autor:
Masahiro Morita, Morgan D. Fullerton, Kaelan Gobeil Odai, Nicholas D. LeBlond, Rebecca A. Yaworski, Sabrin Sanjana, Shauna Han, Conor O’Dwyer, Kaitlyn D. Margison, Tyler T.K. Smith, Tommy Alain, Peyman Ghorbani, Julia R. C. Nunes, Sakie Katsumura
Publikováno v:
Hepatology Communications, Vol 4, Iss 6, Pp 876-889 (2020)
Hepatology Communications
Hepatology Communications
Choline is an essential nutrient and a critical component of the membrane phospholipid phosphatidylcholine (PC), the neurotransmitter acetylcholine, while also contributing to the methylation pathway. In the liver specifically, PC is the major membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff303ec65d9f0df719e774c428e99fd
https://doaj.org/article/6f21bd4cf0e644f38c1cf1dba71d17bc
https://doaj.org/article/6f21bd4cf0e644f38c1cf1dba71d17bc
Autor:
Ning Wang, Chris P. Barnes, Suraiya Dubash, Diana Brickute, Cen Chen, Marta Braga, Eric O. Aboagye, Marianna Inglese, Yunqing Li, Kathrin Heinzmann, Ruisi Fu, Alice Beckley, Haonan Lu, Louis Allott, Laurence Carroll
Publikováno v:
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1246, p 1246 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1246, p 1246 (2021)
Hypoxia is a complex microenvironmental condition known to regulate choline kinase α (CHKA) activity and choline transport through transcription factor hypoxia-inducible factor-1α (HIF-1α) and, therefore, may confound the uptake of choline radiotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276afc69ae2d9b74c0578b904c079290
http://hdl.handle.net/10044/1/90990
http://hdl.handle.net/10044/1/90990
Autor:
Dirk Klee, Eva Kildall Hejbøl, Ljubo Markovic, Marica Bakovic, Mark A. Tarnopolsky, Lauren Brady, Vernon W. Dolinsky, Maria Kibaek, Annette Seibt, Prasoon Agarwal, Else Gade, Rami Abou Jamra, Henrik Daa Schrøder, Martin Jakob Larsen, Adrian Taylor, Peter L. Nagy, Dagmar Wieczorek, Felix Distelmaier, Christina Fagerberg, Nicholas A. Rouse
Publikováno v:
Fagerberg, C R, Taylor, A, Distelmaier, F, Schrøder, H D, Kibæk, M, Wieczorek, D, Tarnopolsky, M, Brady, L, Larsen, M J, Jamra, R A, Seibt, A, Hejbøl, E K, Gade, E, Markovic, L, Klee, D, Nagy, P, Rouse, N, Agarwal, P, Dolinsky, V W & Bakovic, M 2020, ' Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration ', Brain : a journal of neurology, vol. 143, no. 1, pp. 94-111 . https://doi.org/10.1093/brain/awz376
Cerebral choline metabolism is crucial for normal brain function, and its homoeostasis depends on carrier-mediated transport. Here, we report on four individuals from three families with neurodegenerative disease and homozygous frameshift mutations (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac0861f3b693c401a937475d42f4898
https://doi.org/10.1093/brain/awz376
https://doi.org/10.1093/brain/awz376
Autor:
Eryn Donovan, Cassandra Avila, Sarah Klausner, Vinay Parikh, Cristina Fenollar-Ferrer, Randy D. Blakely, Martin Sarter
Transport of choline via the neuronal high-affinity choline transporter (CHT; SLC5A7) is essential for cholinergic terminals to synthesize and release acetylcholine (ACh). In humans, we previously demonstrated an association between a common CHT codi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66ada3a499b58183355bfc9d079b2ec6
https://doi.org/10.1101/2021.06.27.450076
https://doi.org/10.1101/2021.06.27.450076
Autor:
Shuang Yang, Bo Yang, Weibin Song, He Tian, Haihong Liu, Guanghou Shui, Haiming Zhao, Lizhu E, Zongliang Chen, Mingjian Hu, Jinsheng Lai
Publikováno v:
The New phytologist. 232(6)
Maize kernel weight is influenced by the unloading of nutrients from the maternal placenta and their passage through the transfer tissue of the basal endosperm transfer layer (BETL) and the basal intermediate zone (BIZ) to the upper part of the endos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db6b307a8f344f582eadeb125752ee6
https://pubmed.ncbi.nlm.nih.gov/34559890
https://pubmed.ncbi.nlm.nih.gov/34559890
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1990 Jun 01. 87(11), 4280-4283.
Externí odkaz:
https://www.jstor.org/stable/2354934
Publikováno v:
Applied and Environmental Microbiology. 87
Dimethylsulfoniopropionate (DMSP) is a key component of the global geochemical sulfur cycle that is a secondary metabolite produced in large quantities by marine phytoplankton and utilized as an osmoprotectant. Bacterial DMSP lyases convert DMSP to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b260ff3d837da2ecc410a7eecddd525
https://doi.org/10.1128/aem.02235-20
https://doi.org/10.1128/aem.02235-20