Zobrazeno 1 - 10
of 499
pro vyhledávání: '"Cholesterol Trafficking"'
Autor:
Ngoc Vu, Tobias M. Maile, Sudha Gollapudi, Aleksandr Gaun, Phillip Seitzer, Jonathon J. O’Brien, Sean R. Hackett, Jose Zavala-Solorio, Fiona E. McAllister, Ganesh Kolumam, Rob Keyser, Bryson D. Bennett
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100607- (2024)
Blood plasma is one of the most commonly analyzed and easily accessible biological samples. Here, we describe an automated liquid-liquid extraction platform that generates accurate, precise, and reproducible samples for metabolomic, lipidomic, and pr
Externí odkaz:
https://doaj.org/article/4c2c7606b1f34ce2a12d36d49f908b45
Autor:
Ciro Acosta S, Díaz-Ordóñez L, Gutierrez-Medina JD, Silva-Cuero YK, Arango-Vélez LG, García-Trujillo AO, Pachajoa H
Publikováno v:
The Application of Clinical Genetics, Vol Volume 17, Pp 23-32 (2024)
Sebastian Ciro Acosta,1 Lorena Díaz-Ordóñez,1,2 Juan David Gutierrez-Medina,1,3 Yisther Katherine Silva-Cuero,1,2 Luis Guillermo Arango-Vélez,4,5 Andrés Octavio García-Trujillo,4,5 Harry Pachajoa1,2,6 1Centro de Investigaciones en Anomalias Con
Externí odkaz:
https://doaj.org/article/7478282521b644af9444988cd5740ed4
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 12, Pp 100465- (2023)
Accurate intracellular cholesterol traffic plays crucial roles. Niemann Pick type C (NPC) proteins NPC1 and NPC2, are two lysosomal cholesterol transporters that mediate the cholesterol exit from lysosomes. However, other proteins involved in this pr
Externí odkaz:
https://doaj.org/article/6077709dd9d34e4da493820344f2a460
Autor:
Dongun Lee, Jeong Hee Hong
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2021 (2023)
Cholesterol trafficking is initiated by the endocytic pathway and transported from endo/lysosomes to other intracellular organelles. Deficiencies in cholesterol-sensing and binding proteins NPC1 and NPC2 induce accumulation in lysosomes and the malfu
Externí odkaz:
https://doaj.org/article/73a9dce2293547ed877baf1ae82e7155
Akademický článek
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Akademický článek
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Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2615 (2023)
Lipids are essential for cellular function and are tightly controlled at the transcriptional and post-transcriptional levels. Dysregulation of these pathways is associated with vascular diseases, diabetes, cancer, and several inherited metabolic diso
Externí odkaz:
https://doaj.org/article/b4e95d05aeca4fd3b21f78a96df074d9
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 8, Pp 100243- (2022)
Sortilin is a post-Golgi trafficking receptor homologous to the yeast vacuolar protein sorting receptor 10 (VPS10). The VPS10 motif on sortilin is a 10-bladed β-propeller structure capable of binding more than 50 proteins, covering a wide range of b
Externí odkaz:
https://doaj.org/article/0f1f77c88d1d4de2b4607d797b5bfe0f
Autor:
Youpeng Fan, Jialing Bao, Xiaoyu Fu, Pengfei Wu, Jingya Chen, Yan Huang, Junhong Wei, Guoqing Pan, Chunfeng Li, Zeyang Zhou
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Baculovirus is a powerful tool for biological control in agriculture and foreign gene expression and delivery in insect and mammalian cells. Baculovirus enters host cells by multiple endocytic pathways; however, the current understanding of
Externí odkaz:
https://doaj.org/article/a4487aa82ca34178879a29bda20b77f0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6716 (2023)
LC3b (Map1lc3b) plays an essential role in canonical autophagy and is one of several components of the autophagy machinery that mediates non-canonical autophagic functions. Phagosomes are often associated with lipidated LC3b to promote phagosome matu
Externí odkaz:
https://doaj.org/article/cf985765cc524683a1e8d9d89ba359bb