Zobrazeno 1 - 10 of 136 pro vyhledávání: '"Cholesterol, LDL/blood"'
1
Joint Genetic Inhibition of PCSK9 and CETP and the Association With Coronary Artery Disease
Autor: Arjen J. Cupido, Laurens F. Reeskamp, Aroon D. Hingorani, Chris Finan, Folkert W. Asselbergs, G. Kees Hovingh, Amand F. Schmidt
Publikováno v: JAMA cardiology, 7(9), 955-964. American Medical Association
IMPORTANCE: Cholesteryl ester transfer protein inhibition (CETP) has been shown to increase levels of high-density lipoprotein cholesterol (HDL-C) and reduce levels of low-density lipoprotein cholesterol (LDL-C). Current LDL-C target attainment is lo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d12369f3c3f80b686ac245eef5ecf1
http://www.scopus.com/inward/record.url?scp=85136248359&partnerID=8YFLogxK
Zobrazit plný text záznamu
2
Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes
Autor: Carsten Friis Rundsten, Torben Hansen, Ivan Brandslund, Marta Guindo-Martínez, Mitja I. Kurki, Jose C. Florez, Sílvia Bonàs-Guarch, Aaron Leong, Joanne B. Cole, Kumar Veerapen, Niels Grarup, Josep M. Mercader, Mark J. O'Connor, Allan Linneberg, Varinderpal Kaur, David Torrents, Philip Schroeder, Paula Cortes-Sánchez, Oluf Pedersen, Alicia Huerta-Chagoya
Publikováno v: O'Connor, M J, Schroeder, P, Huerta-Chagoya, A, Cortés-Sánchez, P, Bonàs-Guarch, S, Guindo-Martínez, M, Cole, J B, Kaur, V, Torrents, D, Veerapen, K, Grarup, N, Kurki, M, Rundsten, C F, Pedersen, O, Brandslund, I, Linneberg, A, Hansen, T, Leong, A, Florez, J C & Mercader, J M 2022, ' Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes ', Diabetes, vol. 71, no. 3, pp. 554-565 . https://doi.org/10.2337/db21-0545
Diabetes
Most genome-wide association studies (GWAS) of complex traits are performed using models with additive allelic effects. Hundreds of loci associated with type 2 diabetes have been identified using this approach. Additive models, however, can miss loci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db48eb07b0bc907f358504be55446e94
https://portal.findresearcher.sdu.dk/da/publications/828dd316-3d73-43bd-ad39-c4d38447ca63
Zobrazit plný text záznamu
3
The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Autor: Andrey V. Susekov, Amirhossein Sahebkar, Luis E. Simental-Mendía, Tannaz Jamialahmadi, Suowen Xu, Željko Reiner, Raul D. Santos, Fatemeh Baratzadeh
Publikováno v: Mediators of Inflammation
Mediators of Inflammation, Vol 2021 (2021)
Background. Elevated plasma low-density lipoprotein cholesterol (LDL-C) is the main risk factor for atherosclerotic cardiovascular disease (ASCVD). Statins are the drugs of choice for decreasing LDL-C and are used for the prevention and management of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead0f1fb3009a241d38dee2622f5e591
https://pubmed.ncbi.nlm.nih.gov/34526854
Zobrazit plný text záznamu
4
Serum lipids and prostate cancer
Autor: Luís Campos Pinheiro, José C Marta, João Tiago Guimarães, Ruy M. Ribeiro, Manuel M Garrido
Publikováno v: Journal of Clinical Laboratory Analysis
Background Conflicting results are found in the literature relating serum lipids levels and prostate cancer. Some results imply a relationship between them; others contradict this association. The purpose of this study was to investigate a possible a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65b23d8dc20dde5343453ee4a91156a
https://doi.org/10.1002/jcla.23705
Zobrazit plný text záznamu
5
Corneal confocal microscopy identifies small fibre damage and progression of diabetic neuropathy
Autor: Jan Hoong Ho, Ioannis N. Petropoulos, Shaishav Dhage, Andrew Atkinson, Uazman Alam, Maryam Ferdousi, Safwaan Adam, Georgios Ponirakis, Handrean Soran, Shazli Azmi, Alise Kalteniece, Maria Jeziorska, Andrew Marshall, Rayaz A. Malik
Publikováno v: SCIENTIFIC REPORTS
Scientific Reports
Dhage, S, Ferdousi, M, Adam, S, Ho, J H, Kalteniece, A, Azmi, S, Alam, U, Ponirakis, G, Petropoulos, I, Atkinson, A J, Marshall, A, Jeziorska, M, Soran, H & Malik, R A 2021, ' Corneal confocal microscopy identifies small fibre damage and progression of diabetic neuropathy ', Scientific Reports, vol. 11, no. 1, 1859 . https://doi.org/10.1038/s41598-021-81302-8
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Accurately quantifying the progression of diabetic peripheral neuropathy is key to identify individuals who will progress to foot ulceration and to power clinical intervention trials. We have undertaken detailed neuropathy phenotyping to assess the l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8150cd3efbd65beabb01334985afafbb
Zobrazit plný text záznamu
6
Impact of combined training with different exercise intensities on inflammatory and lipid markers in type 2 diabetes: a secondary analysis from a 1-year randomized controlled trial
Autor: João Filipe Raposo, Diana A. Santos, Inês R. Correia, Rogério T. Ribeiro, Andreia Matos, Megan Hetherington-Rauth, Luís B. Sardinha, João P. Magalhães, Manuel Bicho
Publikováno v: Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-11 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cardiovascular Diabetology
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ed174345ddd495bac36325f4f2e167
https://doi.org/10.1186/s12933-020-01136-y
Zobrazit plný text záznamu
7
Controverses sur le dépistage et la prise en charge des dyslipidémies familiales en 2020 [Controversies concerning screening and treatment of primary dyslipidemias in 2020]
Autor: Bretagne, L., Aubert, C., Nanchen, D., Rodondi, N.
Publikováno v: Revue medicale suisse, vol. 16, no. 684, pp. 433-437
Familial dyslipidemia is rare compared to polygenetic causes. Nevertheless, it is important not to miss this diagnosis, as it is more strongly associated with an increased risk of early cardiovascular disease and scores for calculating cardiovascular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::f87b93fbd55bbfcaae24b1285e4a4480
https://serval.unil.ch/notice/serval:BIB_24A64741D9AA
Zobrazit plný text záznamu
8
Association between low density lipoprotein and all cause and cause specific mortality in Denmark:prospective cohort study
Autor: Martin Bødtker Mortensen, Anne Langsted, Camilla Ditlev Lindhardt Johannesen, Børge G. Nordestgaard
Publikováno v: Johannesen, C D L, Langsted, A, Mortensen, M B & Nordestgaard, B G 2020, ' Association between low density lipoprotein and all cause and cause specific mortality in Denmark : prospective cohort study ', BMJ, vol. 371, m4266 . https://doi.org/10.1136/bmj.m4266
The BMJ
Johannesen, C D L, Langsted, A, Mortensen, M B & Nordestgaard, B G 2020, ' Association between low density lipoprotein and all cause and cause specific mortality in Denmark : prospective cohort study ', B M J, vol. 371, m4266 . https://doi.org/10.1136/bmj.m4266
Objective To determine the association between levels of low density lipoprotein cholesterol (LDL-C) and all cause mortality, and the concentration of LDL-C associated with the lowest risk of all cause mortality in the general population. Design Pros
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894c5c751c05f7a73d487bf5849f33c1
https://curis.ku.dk/portal/da/publications/association-between-low-density-lipoprotein-and-all-cause-and-cause-specific-mortality-in-denmark(f222c1ba-aa39-4e0c-b4e0-578725f6a287).html
Zobrazit plný text záznamu
9
The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study
Autor: Ioannidou, A, Watts, EL, Perez-Cornago, A, Platz, EA, Mills, IG, Key, TJ, Travis, RC, PRACTICAL consortium, CRUK, BPC3, CAPS, PEGASUS, Tsilidis, KK, Zuber, V
Publikováno v: PLoS Medicine, Vol 19, Iss 1, p e1003859 (2022)
Ioannidou, A, Watts, E L, Perez-Cornago, A, Platz, E A, Mills, I G, Key, T J, Travis, R C, Tsilidis, K & Zuber, V 2022, ' The relationship between lipoprotein A and other lipids with prostate cancer risk : A multivariable Mendelian randomisation study ', PLoS Medicine, vol. 19, no. 1, e1003859 . https://doi.org/10.1371/journal.pmed.1003859
PRACTICAL consortium, CRUK, BPC3, CAPS, PEGASUS 2022, ' The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study ', PLoS Medicine, vol. 19, no. 1, e1003859 . https://doi.org/10.1371/journal.pmed.1003859
PLoS Medicine
Ioannidou, A, Watts, E L, Perez-Cornago, A, Platz, E A, Mills, I G, Key, T J, Travis, R C, Tsilidis, K K, Zuber, V & PRACTICAL Consortium, CRUK, BPC3, CAPS, PEGASUS 2022, ' The relationship between lipoprotein A and other lipids with prostate cancer risk : A multivariable Mendelian randomisation study ', PLOS Medicine, vol. 19, no. 1, e1003859 . https://doi.org/10.1371/journal.pmed.1003859
e1003859
Nature Methods
Background Numerous epidemiological studies have investigated the role of blood lipids in prostate cancer (PCa) risk, though findings remain inconclusive to date. The ongoing research has mainly involved observational studies, which are often prone t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0503208fc8ba030de528564713f4d57
https://doi.org/10.1371/journal.pmed.1003859
Zobrazit plný text záznamu
10
Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials
Autor: Terje R. Pedersen, Gregory G. Schwartz, Andrew Tonkin, Anastasia Lesogor, Helen M. Colhoun, Christiane Drechsler, Florian Kronenberg, Peter Willeit, John Simes, Paul M. Ridker, Sotirios Tsimikas, Anders G. Olsson, Samia Mora, Paul J. Nestel, Christoph Wanner
Publikováno v: Willeit, P, Ridker, P M, Nestel, P J, Simes, J, Tonkin, A M, Pedersen, T R, Schwartz, G G, Olsson, A G, Colhoun, H M, Kronenberg, F, Drechsler, C, Wanner, C, Mora, S, Lesogor, A & Tsimikas, S 2018, ' Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events : individual patient-data meta-analysis of statin outcome trials ', The Lancet, vol. 392, no. 10155, pp. 1311-1320 . https://doi.org/10.1016/S0140-6736(18)31652-0
BACKGROUND: Elevated lipoprotein(a) is a genetic risk factor for cardiovascular disease in general population studies. However, its contribution to risk for cardiovascular events in patients with established cardiovascular disease or on statin therap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ab7522f95edf8333f4c52f73e98b03
https://doi.org/10.1016/s0140-6736(18)31652-0
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje