Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Choiselle Marius"'
Autor:
Charles D. Giamberardino, Wiley A. Schell, Jennifer L. Tenor, Dena L. Toffaletti, Julia R. Palmucci, Choiselle Marius, Jane-Valeriane K. Boua, Quinlyn Soltow, Robert Mansbach, M. Arthur Moseley, J. Will Thompson, Laura G. Dubois, William Hope, John R. Perfect, Karen Joy Shaw
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Cryptococcal Meningitis (CM) is uniformly fatal if not treated, and treatment options are limited. We previously reported on the activity of APX2096, the prodrug of the novel Gwt1 inhibitor APX2039, in a mouse model of CM. Here, we investiga
Externí odkaz:
https://doaj.org/article/12c94fc2bb48423287573f9192ce65ce
Autor:
Vishal Venkatraman, Anthony J Filiano, Li Xu, Leonard Collins, Emily Luo, Katelyn M Ripple, George C de Castro, Jane-Valeriane K Boua, Choiselle Marius, Charles Giamberardino, Shivanand P Lad, Taufika Islam Williams, Michael S Bereman, Richard S Bedlack
Publikováno v:
Cureus.
Autor:
Xiaolin Wei, Yu Xiang, Derek T. Peters, Choiselle Marius, Tongyu Sun, Ruocheng Shan, Jianhong Ou, Xin Lin, Feng Yue, Wei Li, Kevin W. Southerland, Yarui Diao
Publikováno v:
Mol Cell
The long-range interactions of cis-regulatory elements (cREs) play a central role in gene regulation. cREs can be characterized as accessible chromatin sequences. However, it remains technically challenging to comprehensively identify their spatial i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b708dfda4098b2a1d3a21edfc2ea95
https://europepmc.org/articles/PMC8934281/
https://europepmc.org/articles/PMC8934281/
Autor:
Tiffany Ejikeme, Aaron McCabe, George C. de Castro, Gordon Smilnak, Choiselle Marius, Charles Giamberardino, Jane-Valeriane Boua, Promila Pagadala, Katelyn Ripple, Sarah E Hodges, Yutong Chen, Pakawat Chongsathidkiet, Laura Zitella Verbick, Andrew Bartuska, Shivanand P. Lad
Publikováno v:
Neuro-oncology Advances
BackgroundLeptomeningeal metastases (LM), late-stage cancer when malignant cells migrate to the subarachnoid space (SAS), have an extremely poor prognosis. Current treatment regimens fall short in effectively reducing SAS tumor burden. Neurapheresis
Autor:
Laura Zitella Verbick, Katelyn Ripple, Charles Giamberadino, Peter E. Fecci, Shivanand P. Lad, George C. de Castro, Choiselle Marius, Aaron McCabe, Yutong Chen
Publikováno v:
Neuro Oncol
Leptomeningeal Metastases, a severe late stage form of cancer progression in which malignant cells metastasize to the subarachnoid space (SAS) and leptomeninges, has a mean survival rate of 3–6 months with treatment. Standard of care intrathecal ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7aafa542daae68d03c16a2ef241ad7
https://europepmc.org/articles/PMC6847306/
https://europepmc.org/articles/PMC6847306/
Autor:
John R. Perfect, Jennifer L. Tenor, Quinlyn A. Soltow, Jane-Valeriane Boua, Julia R Palmucci, Dena L. Toffaletti, Karen J Shaw, Charles Giamberardino, Choiselle Marius
Publikováno v:
Open Forum Infectious Diseases
Background Cryptococcal meningitis (CM), caused primarily by Cryptococcus neoformans, is uniformly fatal if not treated. Treatment options are limited especially in resource-poor geographical regions, and mortality rates remain high despite current t