Výsledky vyhledávání - "Choi Dong-Young"

Akademický článek

Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer’s disease mice model

Autor: Jin Peng, Kim Jin-A, Choi Dong-Young, Lee Young-Jung, Jung Heon Sang, Hong Jin Tae

Publikováno v: Journal of Neuroinflammation, Vol 10, Iss 1, p 2 (2013)

Abstract Background Alzheimer’s disease (AD) is pathologically characterized by excessive accumulation of amyloid-beta (Aβ) fibrils within the brain and activation of astrocytes and microglial cells. In this study, we examined anti-inflammatory an

Externí odkaz: https://doaj.org/article/37f98fd861fa4114ac923fd3923a715f

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Akademický článek

Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models

Autor: Lee Young-Jung, Choi Dong-Young, Choi Im Seop, Kim Ki Ho, Kim Young Hee, Kim Hwan Mook, Lee Kiho, Cho Won Gil, Jung Jea Kyung, Han Sang Bae, Han Jin-Yi, Nam Sang-Yoon, Yun Young Won, Jeong Jae Hwang, Oh Ki-Wan, Hong Jin Tae

Publikováno v: Journal of Neuroinflammation, Vol 9, Iss 1, p 35 (2012)

Abstract Background Neuroinflammation is important in the pathogenesis and progression of Alzheimer disease (AD). Previously, we demonstrated that lipopolysaccharide (LPS)-induced neuroinflammation caused memory impairments. In the present study, we

Externí odkaz: https://doaj.org/article/59b9cc596b3144248b9b17352b73bced

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Akademický článek

Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells

Autor: Choi Im Seup, Choi Dong-Young, Lee Young-Jung, Han Jin-Yi, Jeong Heon-Sang, Han Sang Bae, Oh Ki-Wan, Hong Jin Tae

Publikováno v: Journal of Neuroinflammation, Vol 8, Iss 1, p 132 (2011)

Abstract Background Amyloidogenesis is linked to neuroinflammation. The tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal, possesses anti-inflammatory properties in cultured macrophages, and in an arthritis animal model.

Externí odkaz: https://doaj.org/article/5178e6980a6c4ad189faf91d14994359

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Akademický článek

Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease

Autor: Hunter Randy L, Nguyen Xuan V, Choi Dong-Young, Liu Mei, Vijitruth Rattanavijit, Bing Guoying

Publikováno v: Journal of Neuroinflammation, Vol 3, Iss 1, p 6 (2006)

Abstract Background Accumulating evidence suggests that inflammation plays an important role in the progression of Parkinson's disease (PD). Among many inflammatory factors found in the PD brain, cyclooxygenase (COX), specifically the inducible isofo

Externí odkaz: https://doaj.org/article/ecd709e82dbf40449f8441f3e76aa545

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