A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Autor: Luo, Yang, Kanai, Masahiro, Choi, Wanson, Li, Xinyi, Sakaue, Saori, Yamamoto, Kenichi, Ogawa, Kotaro, Gutierrez-Arcelus, Maria, Gregersen, Peter K, Stuart, Philip E, Elder, James T, Forer, Lukas, Schönherr, Sebastian, Fuchsberger, Christian, Smith, Albert V, Fellay, Jacques, Carrington, Mary, Haas, David W, Guo, Xiuqing, Palmer, Nicholette D, Chen, Yii-Der Ida, Rotter, Jerome I, Taylor, Kent D, Rich, Stephen S, Correa, Adolfo, Wilson, James G, Kathiresan, Sekar, Cho, Michael H, Metspalu, Andres, Esko, Tonu, Okada, Yukinori, Han, Buhm, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, McLaren, Paul J, Raychaudhuri, Soumya

Publikováno v: Nature genetics, vol 53, iss 10

Fine-mapping to plausible causal variation may be more effective in multi-ancestry cohorts, particularly in the MHC, which has population-specific structure. To enable such studies, we constructed a large (n = 21,546) HLA reference panel spanning fiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::329d76fb7453e7000fb07cc835225d4e
https://escholarship.org/uc/item/7tn6c268

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Analysis of differences in human leukocyte antigen between the two Wellcome Trust Case Control Consortium control datasets.

Autor: Jang CS; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea., Choi W; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea., Cook S; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea., Han B; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.

Publikováno v: Genomics & informatics [Genomics Inform] 2019 Sep; Vol. 17 (3), pp. e29. Date of Electronic Publication: 2019 Sep 27.