Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Choah, Kim"'
Publikováno v:
Journal of Microbiology & Biology Education, Vol 24, Iss 1 (2023)
ABSTRACT In various formats, students at the secondary and postsecondary levels participate in multiweek authentic science research projects. There have been many papers explaining the operations of such programs, but few have provided explicit instr
Externí odkaz:
https://doaj.org/article/19a315f8c2ea48b29bd0716623386775
Autor:
Yiming Zhou, Choah Kim, Juan Lorenzo B. Pablo, Fan Zhang, Ji Yong Jung, Li Xiao, Silvana Bazua-Valenti, Maheswarareddy Emani, Corey R. Hopkins, Astrid Weins, Anna Greka
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Podocyte injury and the appearance of proteinuria are key features of several progressive kidney diseases. Genetic deletion or selective inhibition of TRPC5 channels with small-molecule inhibitors protects podocytes in rodent models of kidney disease
Externí odkaz:
https://doaj.org/article/63a32a6e578a4a1fb96f6f3d356e4283
Autor:
Nicolas Wieder, Juliana Coraor Fried, Choah Kim, Eriene-Heidi Sidhom, Matthew R. Brown, Jamie L. Marshall, Carlos Arevalo, Moran Dvela-Levitt, Maria Kost-Alimova, Jonas Sieber, Katlyn R. Gabriel, Julian Pacheco, Clary Clish, Hamdah Shafqat Abbasi, Shantanu Singh, Justine Rutter, Martine Therrien, Haejin Yoon, Zon Weng Lai, Aaron Baublis, Renuka Subramanian, Ranjan Devkota, Jonnell Small, Vedagopuram Sreekanth, Myeonghoon Han, Donghyun Lim, Anne E. Carpenter, Jason Flannick, Hilary Finucane, Marcia C. Haigis, Melina Claussnitzer, Eric Sheu, Beth Stevens, Bridget K. Wagner, Amit Choudhary, Jillian L. Shaw, Juan Lorenzo Pablo, Anna Greka
Publikováno v:
bioRxiv
SummaryCellular exposure to free fatty acids (FFA) is implicated in the pathogenesis of obesity-associated diseases. However, studies to date have assumed that a few select FFAs are representative of broad structural categories, and there are no scal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daa44ca6aa3c52a2ff38c29c3f14b60
https://doi.org/10.1101/2023.02.19.529127
https://doi.org/10.1101/2023.02.19.529127
Autor:
Corey R. Hopkins, Fan Zhang, Choah Kim, Juan Lorenzo B. Pablo, Astrid Weins, Li Xiao, Maheswarareddy Emani, Anna Greka, Ji Yong Jung, Yiming Zhou, Silvana Bazua-Valenti
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 8 (2021)
Frontiers in Medicine, Vol 8 (2021)
Podocyte injury and the appearance of proteinuria are key features of several progressive kidney diseases. Genetic deletion or selective inhibition of TRPC5 channels with small-molecule inhibitors protects podocytes in rodent models of kidney disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6236b73a891739d1c3a7d50e3a99396
https://doi.org/10.3389/fmed.2021.721865
https://doi.org/10.3389/fmed.2021.721865
Autor:
Keith Keller, Michelle Melanson, Choah Kim, Jillian L. Shaw, Luciene Ronco, Jamie L. Marshall, Katherine A. Vernon, Anna Greka, Juan Lorenzo B. Pablo, Seth L. Alper, Eriene-Heidi Sidhom, Florence F. Wagner, George C. Tsokos, Elizabeth J. Grinkevich, Moran Dvela-Levitt, Matthew Racette, Valeria Padovano, Julie Roignot, Frederick W.K. Tam, Abbe Clark, Ayshwarya Subramanian, Jean Santos, Alissa Campbell, Astrid Weins, Juan Gutierrez, Abhigyan Satyam, Andrew J.B. Watts, Stephen P. McAdoo, Maheswarareddy Emani, Silvana Bazua-Valenti, Estefanía Reyes-Bricio, Maria Kost-Alimova, Juliana Coraor, Brian T. Chamberlain, Patrick J. Byrne, Rebecca Thompson
Publikováno v:
Cell Reports Medicine
bioRxiv
bioRxiv
Drug repurposing is the only method capable of delivering treatments on the shortened time-scale required for patients afflicted with lung disease arising from SARS-CoV-2 infection. Mucin-1 (MUC1), a membrane-bound molecule expressed on the apical su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac05c8ae52c2a9ddd2eedf3972ff732d
http://hdl.handle.net/10044/1/83980
http://hdl.handle.net/10044/1/83980
Autor:
Alissa Campbell, Katherine A. Vernon, Rebecca Thompson, Anna Greka, Julie Roignot, Silvana Bazua-Valenti, Eriene-Heidi Sidhom, Florence F. Wagner, Seth L. Alper, Frederick W.K. Tam, Matthew Racette, Abbe Clark, Michelle Melanson, Ayshwarya Subramanian, Jean Santos, Choah Kim, Estefania Reyes Bricio, Astrid Weins, George C. Tsokos, Jillian L. Shaw, Elizabeth J. Grinkevich, Juliana Coraor, Andrew J. R. Watts, Lucienne V. Ronco, Juan Gutierrez, Keith Keller, Moran Dvela-Levitt, Maria Alimova, Maheswarareddy Emani, Juan Pablo, Abhigyan Satyam, Valeria Padovano, Stephen P. McAdoo, Brian T. Chamberlain, Jamie L. Marshall
Publikováno v:
Cell Reports Medicine
Summary Drug repurposing has the advantage of identifying potential treatments on a shortened timescale. In response to the pandemic spread of SARS-CoV-2, we took advantage of a high-content screen of 3,713 compounds at different stages of clinical d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014b2c3625f75412ce10742b925a6461
https://doi.org/10.1101/2020.06.30.180380
https://doi.org/10.1101/2020.06.30.180380
Autor:
Catarina M. Quinzii, Giulio Kleiner, Clary B. Clish, Katherine A. Vernon, Keith Keller, Anna Greka, Choah Kim, May Theng Ting, Astrid Weins, Andrew J.B. Watts, Nicolas Wieder, Eriene-Heidi Sidhom, Maria Kost-Alimova, Matthew Racette, Elizabeth J. Grinkevich, Jillian L. Shaw, Estefanía Reyes-Bricio, Jamie L. Marshall, Fei Chen, Julian Avila-Pacheco
Publikováno v:
J Clin Invest
Mutations affecting mitochondrial coenzyme Q (CoQ) biosynthesis lead to kidney failure due to selective loss of podocytes, essential cells of the kidney filter. Curiously, neighboring tubular epithelial cells are spared early in disease despite highe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf73d331567498a261ebe776f2ae76d
https://pubmed.ncbi.nlm.nih.gov/33444290
https://pubmed.ncbi.nlm.nih.gov/33444290
Publikováno v:
Journal of the Korean Society of Water and Wastewater. 30:33-40
In this study, a fluorescent silica nano particle is used as the surrogate for challenging test of membrane surface integrity. The particles are functionalized by a fluorescent dying agent so that as an ultraviolet light is imposed a bright fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0220db8d7833bbead427a549341e1d48
https://doi.org/10.11001/jksww.2016.30.1.033
https://doi.org/10.11001/jksww.2016.30.1.033
Autor:
Roberto Zoncu, David M. Sabatini, William C. Comb, Bernardo L. Sabatini, Lynne Chantranupong, Rachel L. Wolfson, Molly Plovanich, Zhi-Yang Tsun, Shuyu Wang, Choah Kim, Christoph Straub, Kuang Shen, Tony D. Jones, Liron Bar-Peled, Timothy C. Wang, Gregory A. Wyant, Jiwon Park, Elizabeth D. Yuan
Publikováno v:
Science. 347:188-194
Sensing amino acids at the lysosome The mTORC1 protein kinase is a complex of proteins that functions to regulate growth and metabolism. Activity of mTORC1 is sensitive to the abundance of amino acids, but how the sensing of amino acids is coupled to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::259f592afc83adcbed0273904f3e896f
https://doi.org/10.1126/science.1257132
https://doi.org/10.1126/science.1257132
Autor:
Sidhom, Eriene-Heidi1,2, Choah Kim1,2, Kost-Alimova, Maria2, Theng Ting, May3, Keller, Keith4, Avila-Pacheco, Julian2, Watts, Andrew J. B.1,2, Vernon, Katherine A.1,2, Marshall, Jamie L.2, Reyes-Bricio, Estefanía2, Racette, Matthew2, Wieder, Nicolas1,2, Kleiner, Giulio3, Grinkevich, Elizabeth J.2, Fei Chen2, Weins, Astrid4, Clish, Clary B.2, Shaw, Jillian L.2, Quinzii, Catarina M.3, Greka, Anna1,2,5 agreka@bwh.harvard.edu
Publikováno v:
Journal of Clinical Investigation. Mar2021, Vol. 131 Issue 5, p1-16. 17p.