Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chlorproguanil/dapsone/artesunate"'
Autor:
Brian Greenwood, Peter Winstanley, Stephan Duparc, Tsiri Agbenyega, Emma J. Harrell, Li-Ean Goh, J O Awobusuyi, Allan Pamba, Nick Carter, Alassane Dicko, Stephen A. Ward, Alfred B. Tiono, Simon L. Pitmang, Dennis A Ndububa
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 81:969-978
This multi-center, randomized, parallel-group, double-blind, double-dummy study compared the efficacy and safety of chlorproguanil–dapsone–artesunate (CDA) and chlorproguanil–dapsone (CPG–DDS) in the treatment of falciparum malaria in Africa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ce4c7bdc2898c8d6b7f12825f5f309
https://doi.org/10.4269/ajtmh.2009.09-0351
https://doi.org/10.4269/ajtmh.2009.09-0351
Autor:
Peter Winstanley, Stephan Duparc, Ann K. Miller, Daniel G. Wootton, Paula L. Kirby, Nibedita Bandyopadhyay, Stephen A. Ward
Publikováno v:
European Journal of Clinical Pharmacology. 65:977-987
Chlorproguanil (CPG)-dapsone (DDS)-artesunate was in development for the treatment of uncomplicated Plasmodium falciparum malaria. The pharmacokinetics of CPG, DDS, artesunate and their metabolites chlorcycloguanil (CCG), monoacetyl dapsone (MADDS) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b1e0a0f555ec68ed3ced8e54d6a1ef
https://doi.org/10.1007/s00228-009-0672-1
https://doi.org/10.1007/s00228-009-0672-1
Publikováno v:
Experimental Parasitology. 121:376-380
Resistance to antimalarial antifolates necessitates a search for new antimetabolites targeting other enzymes of the folate metabolic pathway. In this study, 5-fluoroorotate (FOA), reported to be an inhibitor of thymidylate synthase, was assayed again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19abb72b0f9bf6ca2673e5c4b8a6a97
https://doi.org/10.1016/j.exppara.2009.01.009
https://doi.org/10.1016/j.exppara.2009.01.009
Autor:
V. Ndahindwa, Aline Uwimana, Daniel Ngamije, Umberto D'Alessandro, J. Curtis, Corine Karema, W. van Doren, C. Van Overmeir, Caterina I. Fanello
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 102:412-420
We tested the efficacy and safety of chlorproguanil/dapsone co-administered with artesunate (CD+A) for the treatment of uncomplicated Plasmodium falciparum malaria in children compared with amodiaquine+sulfadoxine/pyrimethamine (AQ+SP) at two differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb6960327bf041f7f1d661495a6e579
https://doi.org/10.1016/j.trstmh.2008.01.013
https://doi.org/10.1016/j.trstmh.2008.01.013
Autor:
Magdalena M. Szafran, Ben Bardsley, Stephen A. Hancock, Malgorzata A. Drozdz, Samantha J. Barry, George Okafo
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 54(3)
Chlorproguanil hydrochloride, dapsone and artesunate are three compounds with anti-malarial properties developed as a triple combination drug product (Dacart™) for the treatment of malarial infections. During long-term stability studies, a degradan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cccd5a354e179701d46f17ef5d0a4bb9
https://pubmed.ncbi.nlm.nih.gov/20970278
https://pubmed.ncbi.nlm.nih.gov/20970278
Autor:
Steffen Borrmann, Stephen Oguche, Fabian Esamai, Akintunde Sowunmi, Stephan Duparc, Lynda Kellam, Stephen A. Ward, Paula L. Kirby, Peter Winstanley, Brian Greenwood, Allan Pamba, R. E. Umeh, Seth Owusu-Agyei, Zul Premji, Robert T. Guiguemdé, Emmanuel U. Ezedinachi
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6682 (2009)
PLoS ONE
PLoS ONE
BACKGROUND Chlorproguanil-dapsone-artesunate (CDA) was developed as an affordable, simple, fixed-dose artemisinin-based combination therapy for use in Africa. This trial was a randomized parallel-group, double-blind, double-dummy study to compare CDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49916fdb06a2bdd4831086c5e1e7ca79
http://digitallibrary.ihi.or.tz/208/
http://digitallibrary.ihi.or.tz/208/
Autor:
Aline Uwimana, David Modiano, Umberto D'Alessandro, Pamela Avellino, Corine Karema, Sue J. Lee, Germana Bancone, Caterina I. Fanello
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 12, p e4031 (2008)
PLoS ONE, Vol 3, Iss 12, p e4031 (2008)
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inherited human enzyme defect. This deficiency provides some protection from clinical malaria, but it can also cause haemolysis after administration of drugs with oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc99d83fea4a1b1d5d3226a7ad4a15f
http://hdl.handle.net/11573/364997
http://hdl.handle.net/11573/364997
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