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pro vyhledávání: '"Chlorproguanil/dapsone"'
Akademický článek
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Publikováno v:
Journal of Infection in Developing Countries, Vol 2, Iss 2, Pp 135-139 (2008)
Background: Malaria infection during pregnancy is a major public health problem. Due to increasing resistance to Chloroquine and Sulphadoxine/Pyrimethamine, the Ugandan national policy on malaria treatment was changed in 2005 to Artemisinin-based com
Externí odkaz:
https://doaj.org/article/3c615fbb52ae40138861a1a476f5c427
Autor:
Van Malderen Carine, Van Geertruyden Jean-Pierre, Machevo Sonia, González Raquel, Bassat Quique, Talisuna Ambrose, Yeka Adoke, Nabasumba Carolyn, Piola Patrice, Daniel Atwine, Turyakira Eleanor, Forret Pascale, Van Overmeir Chantal, Van Loen Harry, Robert Annie, D’ Alessandro Umberto
Publikováno v:
Malaria Journal, Vol 11, Iss 1, p 139 (2012)
Abstract Background Malaria is a leading cause of mortality, particularly in sub-Saharan African children. Prompt and efficacious treatment is important as patients may progress within a few hours to severe and possibly fatal disease. Chlorproguanil-
Externí odkaz:
https://doaj.org/article/77d4505f1dbe411e809c6ce54ded1448
Akademický článek
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Chlorproguanil-dapsone is a recently released antimalarial drug in which two long-established compounds are formulated in a fixed combination. Proguanil which has similar pharmacological properties to chlorproguanil is a biguanide that was introduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829b2da9d239677c3f4792a8d2cf5162
https://doi.org/10.1016/s0140-6736(04)16390-3
https://doi.org/10.1016/s0140-6736(04)16390-3
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 35:2584-2601
A sensitive, specific, and rapid liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method for the determination of dapsone, chlorproguanil, and their metabolites was developed and validated over a concentration range of 2–2000 ng/mL using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9d22c4bee2b69805e5465b0482e9ff
https://doi.org/10.1080/10826076.2011.637269
https://doi.org/10.1080/10826076.2011.637269
Autor:
Brian Greenwood, Peter Winstanley, Stephan Duparc, Tsiri Agbenyega, Emma J. Harrell, Li-Ean Goh, J O Awobusuyi, Allan Pamba, Nick Carter, Alassane Dicko, Stephen A. Ward, Alfred B. Tiono, Simon L. Pitmang, Dennis A Ndububa
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 81:969-978
This multi-center, randomized, parallel-group, double-blind, double-dummy study compared the efficacy and safety of chlorproguanil–dapsone–artesunate (CDA) and chlorproguanil–dapsone (CPG–DDS) in the treatment of falciparum malaria in Africa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ce4c7bdc2898c8d6b7f12825f5f309
https://doi.org/10.4269/ajtmh.2009.09-0351
https://doi.org/10.4269/ajtmh.2009.09-0351
Autor:
Peter Winstanley, Stephan Duparc, Ann K. Miller, Daniel G. Wootton, Paula L. Kirby, Nibedita Bandyopadhyay, Stephen A. Ward
Publikováno v:
European Journal of Clinical Pharmacology. 65:977-987
Chlorproguanil (CPG)-dapsone (DDS)-artesunate was in development for the treatment of uncomplicated Plasmodium falciparum malaria. The pharmacokinetics of CPG, DDS, artesunate and their metabolites chlorcycloguanil (CCG), monoacetyl dapsone (MADDS) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b1e0a0f555ec68ed3ced8e54d6a1ef
https://doi.org/10.1007/s00228-009-0672-1
https://doi.org/10.1007/s00228-009-0672-1
Autor:
V. Ndahindwa, Aline Uwimana, Daniel Ngamije, Umberto D'Alessandro, J. Curtis, Corine Karema, W. van Doren, C. Van Overmeir, Caterina I. Fanello
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 102:412-420
We tested the efficacy and safety of chlorproguanil/dapsone co-administered with artesunate (CD+A) for the treatment of uncomplicated Plasmodium falciparum malaria in children compared with amodiaquine+sulfadoxine/pyrimethamine (AQ+SP) at two differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb6960327bf041f7f1d661495a6e579
https://doi.org/10.1016/j.trstmh.2008.01.013
https://doi.org/10.1016/j.trstmh.2008.01.013
Autor:
William A. Watkins, Leon Aarons, Dyfrig A. Hughes, Julie A. Simpson, Steve A. Ward, Peter Winstanley, Kalifa Bojang, Geoffrey Edwards, Christine Manyando
Publikováno v:
British Journal of Clinical Pharmacology. 61:289-300
Aims To determine the population pharmacokinetics of chlorproguanil, dapsone and the active metabolite of chlorproguanil, chlorcycloguanil; and to estimate the duration of parasitocidal activity for chlorpoguanil/dapsone against Plasmodium falciparum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e228a5f2c72b1acd949736ac6bee8cde
https://doi.org/10.1111/j.1365-2125.2005.02567.x
https://doi.org/10.1111/j.1365-2125.2005.02567.x