Zobrazeno 1 - 10
of 441
pro vyhledávání: '"Chloroethylclonidine"'
Autor:
Kai Xu, Yueliang Shen, Liqing Jiang, Naiji Shen, Qingmao Chen, Yingying Chen, Yuan Chen, Hualiang Liu, Jifeng Zheng
Publikováno v:
European Journal of Pharmacology. 730:164-170
Kir2.1 channel is a typical inward rectified channel with little outward currents when the membrane depolarized. Barium blocks the inward Kir2.1 currents in a voltage-dependent manner. However, in this study we found that barium would impair the rect
Autor:
Maleeha Azam, Nor Aniza Abdullah, Edward J. Johns, Safia Akhtar Khan, Munavvar A. Sattar, Fayyaz Hashmi, Ashfaq Ahmad, Mohammed H. Abdulla
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154995 (2016)
PLoS ONE
PLoS ONE
The purpose of the present study was to investigate the interaction between H2S and NO (nitric oxide) in the kidney and to evaluate its impact on the functional contribution of ?1A and ?1B-adrenoreceptors subtypes mediating the renal vasoconstriction
Autor:
Rolando Hernández-Muñoz, Juan Pablo Pardo, S. G. Martínez-Salas, A. Tanoue, M. Ibarra, Gozoh Tsujimoto, J. M. Campos-Peralta, Rafael Villalobos-Molina
Publikováno v:
Autonomic and Autacoid Pharmacology. 31:64-71
Summary 1 The pressor action of the α1A-adrenoceptor (α1A-AR) agonist A61603 (N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl] methanesulfonamide) and the α1-ARs agonist phenylephrine and their blockade by selective
Autor:
Akifumi Togari, Daisuke Kodama
Publikováno v:
Neuroscience Letters. 485:102-106
Recent studies have demonstrated the involvement of the sympathetic nerve system in bone metabolism. We have previously demonstrated the expression of adrenergic receptors in the human osteoblast SaM-1 cell line. The aim of this study was to reveal t
Autor:
Ashfaq Ahmad, Owais Bhatt, Maleeha Azam, Munavvar A. Sattar, Edward J. Johns, Safia Akhtar Khan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0189386 (2018)
PLoS ONE, Vol 13, Iss 2, p e0189386 (2018)
Left ventricular hypertrophy (LVH) is associated with decreased responsiveness of renal alpha(1)-adrenoreceptors subtypes to adrenergic agonists. Nitric oxide donors are known to have antihypertrophic effects however their impact on responsiveness of
Autor:
Young Seok Jeong, Young-Kyun Chung, Heon-Keun Lee, Kyeong-Eon Park, Ju-Tae Sohn, Hui-Jin Sung, Il Woo Shin
Publikováno v:
Yonsei Medical Journal
Fentanyl was reported to inhibit the alpha(1)-adrenoceptor agonist-induced contraction. The goal of this in vitro study was to identify the alpha(1)-adrenoceptor subtype primarily involved in the fentanyl-induced attenuation of phenylephrine-induced
Publikováno v:
Autonomic and Autacoid Pharmacology. 29:25-31
1 Increased renal vascular resistance is one renal functional abnormality that contributes to hypertension, and alpha(1)-adrenoceptors play a pivotal role in modulating this renal vascular resistance. This study investigates the functional contributi
Publikováno v:
Acta Pharmacologica Sinica. 29:564-572
This study investigates the subtypes of the alpha1-adrenoceptor mediating the adrenergically-induced renal vasoconstrictor responses in streptozotocin-induced diabetic and non-diabetic 2-kidney one clip (2K1C) Goldblatt hypertensive rats.The renal bl
Publikováno v:
British Journal of Pharmacology. 153:1232-1241
Background and purpose: This study investigated whether the α1-adrenoceptor responsiveness of the renal vasculature was altered in the state of hypertension combined with renal failure. Experimental approach: Male spontaneously hypertensive rats (SH
Publikováno v:
Journal of Dietary Supplements. 5:164-175
To test the hypothesis that ma huang induces a pressor response in the pulmonary vascular bed of the cat and identify the alpha (1)-adrenoceptor subtype pathway(s) involved in the mediation or modulation of these effects.Prospective vehicle controlle