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pro vyhledávání: '"Chloe Y. Lee"'
Autor:
Chloe Y. Lee, Stoyan N. Angelov, Jay Zhu, Lianxiang Bi, Nicole Sanford, Ilkay Alp Yildirim, David A. Dichek
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:764-771
Background: To test the hypothesis that smooth muscle cell (SMC) TGF-β (transforming growth factor beta) signaling contributes to maintenance of aortic structure and function beyond the early postnatal period. Methods: We deleted the TBR2 (type 2 TG
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: Altered transforming growth factor beta (TGF-β) signaling in aortic SMC is implicated as a cause of aortic aneurysms and dissections (AAD), with AAD attributed both to increased and decreased TGF-β signaling. Loss of TGF-β signaling in