Výsledky vyhledávání - "Chloe Matovina"

Rationale for Using Irreversible Epidermal Growth Factor Receptor Inhibitors in Combination with Phosphatidylinositol 3-Kinase Inhibitors for Advanced Head and Neck Squamous Cell Carcinoma

Autor: Gabrielle Herbst, Aditi Kulkarni, Micah Harris, Thomas E. Carey, Hui Jiang, Jingyi Zhai, Elizabeth Leonard, J. Chad Brenner, Nicole L. Michmerhuizen, Chloe Matovina

Publikováno v: Mol Pharmacol

Head and neck squamous cell carcinoma (HNSCC) is a common and debilitating form of cancer characterized by poor patient outcomes and low survival rates. In HNSCC, genetic aberrations in phosphatidylinositol 3-kinase (PI3K) and epidermal growth factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea354569229c66c25eb6ee728b79556b
https://doi.org/10.1124/mol.118.115162

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Comprehensive review of genetic factors contributing to head and neck squamous cell carcinoma development in low-risk, nontraditional patients

Autor: Megan L. Ludwig, Nicole L. Michmerhuizen, Samantha N. Devenport, Morgan A. Gingerich, Chad Brenner, Joshua D. Smith, Chloe Matovina, Steven B. Chinn

Publikováno v: Head & Neck. 40:943-954

BACKGROUND: The past two decades have seen an increased incidence of squamous cell carcinoma of the head and neck (HNSCC) in a non-traditional, low-risk patient population (i.e. ≤ 45 years of age, no substance use history), owing to a combination o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f7ba62fb9980e062e0e34c2b6b8a8a
https://doi.org/10.1002/hed.25057

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The association between the COVID-19 pandemic and postpartum care provision

Autor: Chloe Matovina, Maya Daiter, Allie Sakowicz, Emily S. Miller, William A. Grobman, Sidney Imeroni, Olivia Barry

Publikováno v: American Journal of Obstetrics & Gynecology Mfm

The COVID-19 pandemic led to a rapid transformation in the healthcare system to mitigate viral exposure. In the perinatal context, one change included altering the prenatal visit cadence and increasing the utilization of telehealth methods. Whether t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f310c1716ef6d7b432773330fdc364
https://doi.org/10.1016/j.ajogmf.2021.100460

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Surveilling the Potential for Precision Medicine-driven PD-1/PD-L1-targeted Therapy in HNSCC

Autor: Nicole L. Michmerhuizen, N Jawad, T R Vandenberg, Megan L. Ludwig, M.E. Spector, J.C. Brenner, Andrew G. Shuman, Rebecca C. Hoesli, Michelle Mierzwa, Jacqueline E. Mann, Samantha N. Devenport, Chloe Matovina

Publikováno v: Journal of Cancer

Immunotherapy is becoming an accepted treatment modality for many patients with cancer and is now approved for use in platinum-refractory recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). Despite these successes, a minority of pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd31e91248aea8cc28ed55054ca75dc
https://doi.org/10.7150/jca.17547

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Multiple Parotid Masses: A Rare Case of De Novo Monomorphic and Pleomorphic Adenomas in a Patient with Myotonic Dystrophy

Autor: Andrew C. Birkeland, Matthew E. Spector, Chloe Matovina

Publikováno v: Journal of Case Reports in Medicine. 6:1-3

Objective/background. This is a case presentation of a primary multifocal monomorphic and pleomorphic adenoma, with possible association with myotonic dystrophy. Methods/presentation. The patient was a 36-year old woman with myotonic dystrophy with m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7965a121863987ae60441b1d5a79c6d
https://doi.org/10.4303/jcrm/235995

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Integrative Medicine in Head and Neck Cancer

Autor: Andrew G. Shuman, Suzanna M. Zick, Andrew C. Birkeland, Chloe Matovina

Publikováno v: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, vol 156, iss 2

Objective Complementary and alternative medicine, or integrative medicine, has become increasingly popular among patients with head and neck cancer. Despite its increasing prevalence, many patients feel uncomfortable discussing such therapies with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28966d69ba8152cdcbddbd47a4111097
https://escholarship.org/uc/item/25k6k0cc

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Abstract 322: Discovery of synergistic PI3K inhibitor combination therapies using high throughput approaches in HNSCC

Autor: Nicole Lynn Michmerhuizen, Elizabeth Leonard, Caitlin Heenan, Vivek Nair, Chloe Matovina, Micah Harris, Gabrielle Herbst, Daniel Kim, Amanda Bachand, Jingyi Zhai, Susan K. Foltin, Aditi Kulkarni, Thomas E. Carey, Carol R. Bradford, Hui Jiang, John C. Brenner

Publikováno v: Cancer Research. 79:322-322

Recent head and neck squamous cell carcinoma (HNSCC) sequencing studies have identified the phosphatidylinositol 3-kinase (PI3K) pathway as the most frequently mutated, oncogenic pathway in this cancer type. Despite frequent activating mutation or am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02c375053256c1fa8eb92c8deaa1199c
https://doi.org/10.1158/1538-7445.am2019-322

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