Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Chloe I. Charendoff"'
Autor:
Ashley G. Boice, Karla E. Lopez, Raj K. Pandita, Melissa J. Parsons, Chloe I. Charendoff, Vijay Charaka, Alexandre F. Carisey, Tej K. Pandita, Lisa Bouchier-Hayes
Publikováno v:
Oncogene. 41:3732-3734
Autor:
Dharaniya Sakthivel, Alexandra Brown-Suedel, Francesca Keane, F. Kenneth McSherry, Chloe I. Charendoff, Kevin Dunne, Dexter Robichaux, Jonathan M. Flanagan, Lisa Bouchier-Hayes
Publikováno v:
Cancer Research. 83:LB035-LB035
Nucleophosmin 1 (NPM1) mutation is the primary genetic lesion in adult acute myeloid leukemia (AML). Typically, a nucleolar protein, NPM1 mutations cause cytoplasmic delocalization of NPM1(NPM1c+), triggering leukemogenesis. Interestingly, NPM1c+ mut
Autor:
Ashley G, Boice, Karla E, Lopez, Raj K, Pandita, Melissa J, Parsons, Chloe I, Charendoff, Vijay, Charaka, Alexandre F, Carisey, Tej K, Pandita, Lisa, Bouchier-Hayes
Publikováno v:
Oncogene. 41(2)
In addition to its classical role in apoptosis, accumulating evidence suggests that caspase-2 has non-apoptotic functions, including regulation of cell division. Loss of caspase-2 is known to increase proliferation rates but how caspase-2 is regulati