Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chloe H, Lee"'
Autor:
Chloe H. Lee, Jaesung Huh, Paul R. Buckley, Myeongjun Jang, Mariana Pereira Pinho, Ricardo A. Fernandes, Agne Antanaviciute, Alison Simmons, Hashem Koohy
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background T-cells play a crucial role in the adaptive immune system by triggering responses against cancer cells and pathogens, while maintaining tolerance against self-antigens, which has sparked interest in the development of various T-ce
Externí odkaz:
https://doaj.org/article/e4fa26aaefb94dcb8391be6331e31555
Autor:
Jelena Čuklina, Chloe H Lee, Evan G Williams, Tatjana Sajic, Ben C Collins, María Rodríguez Martínez, Varun S Sharma, Fabian Wendt, Sandra Goetze, Gregory R Keele, Bernd Wollscheid, Ruedi Aebersold, Patrick G A Pedrioli
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 8, Pp 1-16 (2021)
Abstract Advancements in mass spectrometry‐based proteomics have enabled experiments encompassing hundreds of samples. While these large sample sets deliver much‐needed statistical power, handling them introduces technical variability known as ba
Externí odkaz:
https://doaj.org/article/19902b50778d4e318c792e04483c0f07
Autor:
Chloe H. Lee, Mariana Pereira Pinho, Paul R. Buckley, Isaac B. Woodhouse, Graham Ogg, Alison Simmons, Giorgio Napolitani, Hashem Koohy
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
While individuals infected with coronavirus disease 2019 (COVID-19) manifested a broad range in susceptibility and severity to the disease, the pre-existing immune memory to related pathogens cross-reactive against SARS-CoV-2 can influence the diseas
Externí odkaz:
https://doaj.org/article/cb5d6cdd7c3f41198aaa107f502f7680
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Adaptive immune recognition is mediated by specific interactions between heterodimeric T cell receptors (TCRs) and their cognate peptide-MHC (pMHC) ligands, and the methods to accurately predict TCR:pMHC interaction would have profound clinical, ther
Externí odkaz:
https://doaj.org/article/7ebdfb8b811347709b53843cc76d9ae5
Autor:
Chloe H. Lee, Hashem Koohy
Publikováno v:
F1000Research, Vol 9 (2020)
Background: The newly identified coronavirus known as 2019-nCoV has posed a serious global health threat. According to the latest report (18-February-2020), it has infected more than 72,000 people globally and led to deaths of more than 1,016 people
Externí odkaz:
https://doaj.org/article/88c126f2005240259c44a9a29ef8d0c2
Autor:
Paul R. Buckley, Chloe H. Lee, Mariana Pereira Pinho, Rosana Ottakandathil Babu, Jeongmin Woo, Agne Antanaviciute, Alison Simmons, Graham Ogg, Hashem Koohy
Publikováno v:
Immunology. 166:78-103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50600b092685719db731891e147766ac
https://doi.org/10.1111/imm.13451
https://doi.org/10.1111/imm.13451
Publikováno v:
Immunotherapy Advances. 3
T cell recognition of SARS-CoV-2 antigens after vaccination and/or natural infection has played a central role in resolving SARS-CoV-2 infections and generating adaptive immune memory. However, the clinical impact of SARS-CoV-2-specific T cell respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704b5c7fc188413cbb805db18b1a2c94
https://doi.org/10.1093/immadv/ltad005
https://doi.org/10.1093/immadv/ltad005
Autor:
Franz-Josef Obermair, Florian Renoux, Sebastian Heer, Chloe H. Lee, Nastassja Cereghetti, Marisa Loi, Giulia Maestri, Yannick Haldner, Robin Wuigk, Ohad Iosefson, Pooja Patel, Katherine Triebel, Manfred Kopf, Joanna Swain, Jan Kisielow
Publikováno v:
Science Advances, 8 (17)
Understanding peptide presentation by specific MHC alleles is fundamental for controlling physiological functions of T cells and harnessing them for therapeutic use. However, commonly used in silico predictions and mass spectroscopy have their limita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6aea495b0f3d8f1cf061c7e3fd15053
https://doi.org/10.1126/sciadv.abl5394
https://doi.org/10.1126/sciadv.abl5394
Autor:
Paul R Buckley, Chloe H Lee, Ruichong Ma, Isaac Woodhouse, Jeongmin Woo, Vasily O Tsvetkov, Dmitrii S Shcherbinin, Agne Antanaviciute, Mikhail Shughay, Margarida Rei, Alison Simmons, Hashem Koohy
Publikováno v:
Briefings in Bioinformatics. 23
T cell recognition of a cognate peptide–major histocompatibility complex (pMHC) presented on the surface of infected or malignant cells is of the utmost importance for mediating robust and long-term immune responses. Accurate predictions of cognate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5f3c17e0341cfac81875e305b07c99
https://doi.org/10.1093/bib/bbac141
https://doi.org/10.1093/bib/bbac141
Autor:
Paul R, Buckley, Chloe H, Lee, Mariana, Pereira Pinho, Rosana, Ottakandathil Babu, Jeongmin, Woo, Agne, Antanaviciute, Alison, Simmons, Graham, Ogg, Hashem, Koohy
Publikováno v:
Immunology. 166(1)
The conditions and extent of cross-protective immunity between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and common-cold human coronaviruses (HCoVs) remain open despite several reports of pre-existing T cell immunity to SARS-CoV-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b18cf9f152b99b1536440bd1d979be2d
https://pubmed.ncbi.nlm.nih.gov/35143694
https://pubmed.ncbi.nlm.nih.gov/35143694