Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chloe Goldsmith"'
Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
Autor:
Chloe Goldsmith, Jesús Rafael Rodríguez-Aguilera, Ines El-Rifai, Adrien Jarretier-Yuste, Valérie Hervieu, Olivier Raineteau, Pierre Saintigny, Victoria Chagoya de Sánchez, Robert Dante, Gabriel Ichim, Hector Hernandez-Vargas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whethe
Externí odkaz:
https://doaj.org/article/4221444650b74227b0be0661a1952aaf
Autor:
Iolanda Agliata, Nora Fernandez-Jimenez, Chloe Goldsmith, Julien C. Marie, Jose R. Bilbao, Robert Dante, Hector Hernandez-Vargas
Publikováno v:
Epigenetics, Vol 15, Iss 10, Pp 1068-1082 (2020)
Abnormal DNA methylation has been described in human inflammatory conditions of the gastrointestinal tract, such as inflammatory bowel disease (IBD). As other complex diseases, IBD results from the balance between genetic predisposition and environme
Externí odkaz:
https://doaj.org/article/c9b582c2535140b0b62ca178a3d45177
Publikováno v:
Epigenetics, Vol 15, Iss 5, Pp 511-523 (2020)
In human tumours, the crosstalk between cancer cells and their microenvironment is involved in tumour progression, metastasis and resistance to anti-cancer therapies. Among the factors involved in this exchange of information pro-inflammatory cytokin
Externí odkaz:
https://doaj.org/article/8679ffe927794c3088b60abdaa7246ac
Autor:
Maria I. Matias, Carmen S. Yong, Amir Foroushani, Chloe Goldsmith, Cédric Mongellaz, Erdinc Sezgin, Kandice R. Levental, Ali Talebi, Julie Perrault, Anais Rivière, Jonas Dehairs, Océane Delos, Justine Bertand-Michel, Jean-Charles Portais, Madeline Wong, Julien C. Marie, Ameeta Kelekar, Sandrina Kinet, Valérie S. Zimmermann, Ilya Levental, Laurent Yvan-Charvet, Johannes V. Swinnen, Stefan A. Muljo, Hector Hernandez-Vargas, Saverio Tardito, Naomi Taylor, Valérie Dardalhon
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109911- (2021)
Summary: Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of na
Externí odkaz:
https://doaj.org/article/0c8c5ea249b7400aa1ce379f1a846ac3
Autor:
Chloe Goldsmith, Olivier Fesneau, Valentin Thevin, Maria I. Matias, Julie Perrault, Ali Hani Abid, Naomi Taylor, Valérie Dardalhon, Julien C. Marie, Hector Hernandez-Vargas
Both identity and plasticity of CD4 T helper (Th) cells are regulated in part by epigenetic mechanisms. However, a method that reliably and readily profiles DNA base modifications is still needed to finely study Th cell differentiation. Cytosine meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bb402ab602b3fc8a593f7ea4251689
https://doi.org/10.1101/2023.02.03.527091
https://doi.org/10.1101/2023.02.03.527091
Autor:
Nuria Guerrero-Celis, Félix Recillas-Targa, Victoria Chagoya de Sánchez, Marie-Pierre Cros, Chloe Goldsmith, Jesús Rafael Rodríguez-Aguilera, Szilvia Ecsedi, Mariana Domínguez-López, Rebeca Pérez-Cabeza de Vaca, Isabelle Chemin, Hector Hernandez-Vargas
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.7822. ⟨10.1038/s41598-020-64700-2⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.7822. ⟨10.1038/s41598-020-64700-2⟩
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.7822. ⟨10.1038/s41598-020-64700-2⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.7822. ⟨10.1038/s41598-020-64700-2⟩
A basic question linked to differential patterns of gene expression is how cells reach different fates despite using the same DNA template. Since 5-hydroxymethylcytosine (5hmC) emerged as an intermediate metabolite in active DNA demethylation, there
Autor:
Julie Perrault, Anais Rivière, Chloe Goldsmith, Jonas Dehairs, Cédric Mongellaz, Laurent Yvan-Charvet, Naomi Taylor, Valérie S. Zimmermann, Saverio Tardito, Maria I. Matias, Valerie Dardalhon, Océane Delos, Amir Foroushani, Kandice R. Levental, Stefan A. Muljo, Sandrina Kinet, Ilya Levental, Hector Hernandez-Vargas, Ali Talebi, Jean-Charles Portais, Justine Bertand-Michel, Madeline Wong, Ameeta Kelekar, Julien C. Marie, Johannes V. Swinnen, Carmen S M Yong, Erdinc Sezgin
Publikováno v:
Cell Reports
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of naive CD4 T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a0285e83f2c785c903977fe07dec51
https://lirias.kuleuven.be/handle/20.500.12942/691431
https://lirias.kuleuven.be/handle/20.500.12942/691431
Autor:
Doohyun Kim, Delphine Bousquet, Marie-Laure Plissonnier, Hyoseon Tak, Xavier Grand, Chloe Goldsmith, Françoise Berby, Bordes Isabelle, Alexia Paturel, Aaron Hamilton, Marintha Heil, Massimo Levrero, Barbara Testoni, Fabien Zoulim
Publikováno v:
Journal of Hepatology. 77:S246
Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
Autor:
Robert Dante, Adrien Jarretier-Yuste, Olivier Raineteau, Chloe Goldsmith, Victoria Chagoya de Sánchez, Gabriel Ichim, Hector Hernandez-Vargas, Valérie Hervieu, Pierre Saintigny, Ines El-Rifai, Jesús Rafael Rodríguez-Aguilera
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whether 5mC has
Autor:
Hector Hernandez-Vargas, Robert Dante, Victoria Chagoya de Sánchez, Jesús Rafael Rodríguez-Aguilera, Gabriel Ichim, Valérie Hervieu, Adrien Jarretier, Chloe Goldsmith, Ines El-Rifai
Cytosine DNA methylation in the CpG context (5mCpG) is associated with the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whether 5mCpG has a regulatory role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d84b6354fee1086217bb1cd1c6ea6ff
https://doi.org/10.1101/2020.09.14.296269
https://doi.org/10.1101/2020.09.14.296269