FigureS3 from AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric Models

Autor: Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira

Effect of the combination of treatments in preclinical high-risk HDMB03 models.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0545bd0508683a13750c883231be19da
https://doi.org/10.1158/1078-0432.22477776

Data from AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric Models

Autor: Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira

Purpose:Medulloblastoma is an important cause of mortality and morbidity in pediatric oncology. Here, we investigated whether the DNA repair inhibitor, AsiDNA, could help address a significant unmet clinical need in medulloblastoma care, by improving

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9da6f13b4476dea6cfe675e8466d02
https://doi.org/10.1158/1078-0432.c.6529755.v1

Appendix from AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric Models

Autor: Marie Dutreix, Célio Pouponnot, François D. Boussin, Joel Mispelter, Mihaela Lupu, Sophie Heinrich, Magalie Larcher, Alberto Gatto, Chloe Foray, Sofia Ferreira

Appendix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9321b4b34bd822f6bf86e01e6f3acfb3
https://doi.org/10.1158/1078-0432.22477785.v1

AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric Models

Autor: Chloe Foray, Magalie Larcher, Sofia Ferreira, François D. Boussin, Sophie Heinrich, Marie Dutreix, Mihaela Lupu, Celio Pouponnot, Alberto Gatto, Joel Mispelter

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, American Association for Cancer Research, 2020, 26 (21), pp.5735-5746. ⟨10.1158/1078-0432.CCR-20-1729⟩

Purpose: Medulloblastoma is an important cause of mortality and morbidity in pediatric oncology. Here, we investigated whether the DNA repair inhibitor, AsiDNA, could help address a significant unmet clinical need in medulloblastoma care, by improvin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d68fbf149adf02210c5b19283f529a
https://hal.archives-ouvertes.fr/hal-03043490/file/238693_2_merged_CCR.pdf

Pre-Clinical Development of a Highly Efficient TALEN ®-Based Correction of the β-Globin Gene in Patient-Derived Hematopoietic Stem and Progenitor Cells (HSPCs) to Treat Sickle Cell Disease

Autor: Gil Letort, Sophie Leduc, Mathilde Dusseaux, Tristan Felix, Agnès Gouble, Carrie Brownstein, Louisa Mayer, Cecile Shiffer-Mannoui, Philippe Duchateau, Aymeric Duclert, Selena Kazancioglu, Patrick Hong, Sara Nik, Alex Boyne, Sabrina Lizot, Chloe Foray, Annarita Miccio, Noemie Pinard, Alexa Chirinos, Mark G. Frattini, Anne Chalumeau, Alexandre Juillerat, Giacomo Frati, Arianna Moiani, Sonal Temburni-Blake, Julien Valton

Publikováno v: Blood. 138:1856-1856

Sickle cell disease (SCD) is one of the most common inherited diseases affecting millions of people worldwide. SCD stems from a single point mutation (A>T) in exon 1 of the HBB gene which results in sickle hemoglobin. The only available curative trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ca9d1d3185140c4d53b6bb95b8b4273
https://doi.org/10.1182/blood-2021-153549