Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chloe Cable"'
Autor:
Harrison M. Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Melody Baddoo, Alifiani B. Hartono, Sean B. Lee, Matthew E. Burow, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 391-408 (2019)
Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular c
Externí odkaz:
https://doaj.org/article/7337e8aa807f4d11a94daa9ce23793f7
Autor:
Erik F. Flemington, Sean B. Lee, Sandra Heller, Chloe Cable, Matthew E. Burow, Melody Baddoo, Nathan Ungerleider, Suzana D. Savkovic, Harrison M. Penrose, Susan E. Crawford, Alifiani B. Hartono, Hani Nakhoul
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 391-408 (2019)
Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720f2acd0c056d2a774d3f50b252d021
https://doi.org/10.1016/j.jcmgh.2018.10.003
https://doi.org/10.1016/j.jcmgh.2018.10.003
Autor:
Hani Nakhoul, Susan E. Crawford, Chloe Cable, Nate Ungerleider, Harrison M. Penrose, Sandra Heller, Suzana D. Savkovic, Erik K. Flemington, Zachary F. Pursell, Melody Baddoo
Publikováno v:
Oncoscience
Background Mitochondrial reprogramming has emerged as a hallmark of cancer pathobiology. Although it is believed this reprogramming is essential for cancer cells to thrive, how it supports cancer pathobiology is unclear. We previously generated colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7f7855cd890bfddc38d71dc6aae1b1
http://europepmc.org/articles/PMC5769983
http://europepmc.org/articles/PMC5769983
Autor:
Chloe Cable, Hani Nakhoul, Susan E. Crawford, Sandra Heller, Erik K. Flemington, Melody Baddoo, Suzana D. Savkovic, Harrison M. Penrose, Debjani Biswas
Publikováno v:
The FASEB Journal. 31:2013-2025
Intestinal inflammation is associated with low levels of mucosal ATP, highlighting the importance of mitochondrial function associated with ATP production in the pathophysiology of the disease. In the inflamed colon of humans and mice, we found decre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc9096510dd2e2ca5aef6dc9988dd65
https://doi.org/10.1096/fj.201600976r
https://doi.org/10.1096/fj.201600976r
Autor:
Melody Baddoo, Chloe Cable, Hani Nakhoul, Suzana D. Savkovic, Erik K. Flemington, Susan E. Crawford, Sandra Heller, Harrison M. Penrose
Publikováno v:
Carcinogenesis. 38:302-311
Obesity, an immense epidemic affecting approximately half a billion adults, has doubled in prevalence in the last several decades. Epidemiological data support that obesity, due to intake of a high-fat, western diet, increases the risk of colon cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9def5a033469207f94223898549b68
https://doi.org/10.1093/carcin/bgx001
https://doi.org/10.1093/carcin/bgx001
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 370(3)
Opioid dependence can be difficult to manage using existing pharmacotherapies. A long-acting opioid with low abuse liability that substitutes for a shorter-acting opioid may improve treatment of opioid use disorders (OUDs). We recently characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df935b1f7cdfe2165639a42338e99157
https://pubmed.ncbi.nlm.nih.gov/31213481
https://pubmed.ncbi.nlm.nih.gov/31213481
Autor:
Hani Nakhoul, Nathan Ungerleider, Suzana D. Savkovic, Sandra Heller, Susan E. Crawford, Harrison M. Penrose, Erik K. Flemington, Chloe Cable
Publikováno v:
Gastroenterology. 154:S-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14e400e4e1d864e2630deb1124847e22
https://doi.org/10.1016/s0016-5085(18)30552-3
https://doi.org/10.1016/s0016-5085(18)30552-3
Autor:
Harrison M. Penrose, Ying Chen, Sandra Heller, Susan E. Crawford, Suzana D. Savkovic, Chloe Cable, Gita Chadalawada, Rania Makboul
The proliferation of colon cancer cells is mediated in part by epidermal growth factor receptor (EGFR) signaling and requires sustained levels of cellular energy to meet its high metabolic needs. Intracellular lipid droplets (LDs) are a source of ene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0496de07c9a280b338da8496175eb68a
https://europepmc.org/articles/PMC5607009/
https://europepmc.org/articles/PMC5607009/
Autor:
Rania Makboul, Harrison M. Penrose, Sandra Heller, Susan E. Crawford, Suzana D. Savkovic, Chloe Cable, Debjani Biswas, Maleen Cabe
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 310(10)
Intestinal inflammation has been recently characterized by the dysregulation of lipids as metabolic and energy sources, revealing a novel feature of its pathophysiology. Because intracellular lipids, stored in dynamic lipid droplets (LDs), provide en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d40037779f22c44d3352f5a3df3e8f4
https://pubmed.ncbi.nlm.nih.gov/26968210
https://pubmed.ncbi.nlm.nih.gov/26968210
Autor:
Hani Nakhoul, Suzana D. Savkovic, Harrison M. Penrose, Susan E. Crawford, Sandra Heller, Melody Baddoo, Debjani Biswas, Chloe Cable, Erik K. Flemington
Publikováno v:
Gastroenterology. 152:S412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ec31432a8a0d95764696fa862c4c238
https://doi.org/10.1016/s0016-5085(17)31606-2
https://doi.org/10.1016/s0016-5085(17)31606-2