Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Chloe C Y, Wong"'
Autor:
Radhika Kandaswamy, Eilis Hannon, Louise Arseneault, Georgina Mansell, Karen Sugden, Benjamin Williams, Joe Burrage, James R Staley, Ehsan Pishva, Aisha Dahir, Susanna Roberts, Andrea Danese, Jonathan Mill, Helen L Fisher, Chloe C. Y. Wong
Publikováno v:
Epigenetics, Vol 16, Iss 11, Pp 1169-1186 (2021)
Accumulating evidence suggests that individuals exposed to victimization at key developmental stages may have different epigenetic fingerprints compared to those exposed to no/minimal stressful events, however results are inconclusive. This study aim
Externí odkaz:
https://doaj.org/article/c24e922fd7bc4d3991b7688caaddd685
Autor:
Gokul Ramaswami, Hyejung Won, Michael J. Gandal, Jillian Haney, Jerry C. Wang, Chloe C. Y. Wong, Wenjie Sun, Shyam Prabhakar, Jonathan Mill, Daniel H. Geschwind
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interactions with repetitive and restrictive behaviours. Here the authors integrate mRNA expression, miRNA expression, DNA methylation, and histone acety
Externí odkaz:
https://doaj.org/article/ec12151260b7497e96f2462d590b22b5
Autor:
Antonino Zito, Matthew N. Davies, Pei-Chien Tsai, Susanna Roberts, Rosa Andres-Ejarque, Stefano Nardone, Jordana T. Bell, Chloe C. Y. Wong, Kerrin S. Small
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Skewing of X chromosome inactivation (XCI) occurs when the silencing of one parental X chromosome is non-random. Here, Zito et al. report XCI patterns in lymphoblastoid cell lines, blood, subcutaneous adipose tissue samples and skin samples of monozy
Externí odkaz:
https://doaj.org/article/a930e629700d41afa50c28ffc5023117
Autor:
Ayden Saffari, Matt Arno, Eric Nasser, Angelica Ronald, Chloe C. Y. Wong, Leonard C. Schalkwyk, Jonathan Mill, Frank Dudbridge, Emma L. Meaburn
Publikováno v:
Molecular Autism, Vol 10, Iss 1, Pp 1-15 (2019)
Abstract Background A gap exists in our mechanistic understanding of how genetic and environmental risk factors converge at the molecular level to result in the emergence of autism symptoms. We compared blood-based gene expression signatures in ident
Externí odkaz:
https://doaj.org/article/0437b4b1c786481ea574790327c7c787
Autor:
Luis Alameda, Zhonghua Liu, Pak C. Sham, Monica Aas, Giulia Trotta, Victoria Rodriguez, Marta Di Forti, Simona A. Stilo, Radhika Kandaswamy, Celso Arango, Manuel Arrojo, Miguel Bernardo, Julio Bobes, Lieuwe de Haan, Cristina Marta Del-Ben, Charlotte Gayer-Anderson, Lucia Sideli, Peter B. Jones, Hannah E. Jongsma, James B. Kirkbride, Caterina La Cascia, Antonio Lasalvia, Sarah Tosato, Pierre-Michel Llorca, Paulo Rossi Menezes, Jim van Os, Diego Quattrone, Bart P. Rutten, Jose Luis Santos, Julio Sanjuán, Jean-Paul Selten, Andrei Szöke, Ilaria Tarricone, Andrea Tortelli, Eva Velthorst, Craig Morgan, Emma Dempster, Eilis Hannon, Joe Burrage, Daniella Dwir, Atheeshaan Arumuham, Jonathan Mill, Robin M. Murray, Chloe C. Y. Wong
Publikováno v:
Molecular Psychiatry.
AbtractStudies conducted in psychotic disorders have shown that DNA-methylation (DNAm) is sensitive to the impact of Childhood Adversity (CA). However, whether it mediates the association between CA and psychosis is yet to be explored. Epigenome wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bacd03d8247ecddc0c62174dd83c6a
https://doi.org/10.1038/s41380-023-02044-9
https://doi.org/10.1038/s41380-023-02044-9
Autor:
Eilis Hannon, Olivia Knox, Karen Sugden, Joe Burrage, Chloe C Y Wong, Daniel W Belsky, David L Corcoran, Louise Arseneault, Terrie E Moffitt, Avshalom Caspi, Jonathan Mill
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007544 (2018)
Variation in DNA methylation is being increasingly associated with health and disease outcomes. Although DNA methylation is hypothesized to be a mechanism by which both genetic and non-genetic factors can influence the regulation of gene expression,
Externí odkaz:
https://doaj.org/article/6809e2304b544180b9d0ec8e454447ef
Autor:
Joe Burrage, Chloe C. Y. Wong, Georgina Mansell, Helen L. Fisher, Radhika Kandaswamy, Eilis Hannon, Susanna Roberts, Karen Sugden, Ehsan Pishva, Jonathan Mill, Benjamin Williams, Andrea Danese, Louise Arseneault, Aisha Dahir, James R Staley
Publikováno v:
Epigenetics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Accumulating evidence suggests that individuals exposed to victimization at key developmental stages may have different epigenetic fingerprints compared to those exposed to no/minimal stressful events, however results are inconclusive. This study aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e4737ab819b8b2b5c7baa98204cf86
http://europepmc.org/articles/PMC8813077
http://europepmc.org/articles/PMC8813077
Autor:
Chloe C. Y. Wong, Gokul Ramaswami, Jillian R. Haney, Michael J. Gandal, Jerry C. Wang, Daniel H. Geschwind, Jonathan Mill, Shyam Prabhakar, Wenjie Sun, Hyejung Won
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Autism spectrum disorder (ASD) is a phenotypically and genetically heterogeneous neurodevelopmental disorder. Despite this heterogeneity, previous studies have shown patterns of molecular convergence in post-mortem brain tissue from autistic subjects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5833f1b7b686a63443286e38117ff9e
http://link.springer.com/article/10.1038/s41467-020-18526-1
http://link.springer.com/article/10.1038/s41467-020-18526-1
Autor:
Luis Alameda, Giulia Trotta, Harriet Quigley, Victoria Rodriguez, Romayne Gadelrab, Daniella Dwir, Emma Dempster, Chloe C. Y. Wong, Marta Di Forti
Publikováno v:
Alameda, L, Trotta, G, Quigley, H, Rodriguez, V, Gadelrab, R, Dwir, D, Dempster, E, Wong, C C Y & Forti, M D 2022, ' Can epigenetics shine a light on the biological pathways underlying major mental disorders? ', Psychological Medicine, vol. 52, no. 9, pp. 1645-1665 . https://doi.org/10.1017/S0033291721005559
A significant proportion of the global burden of disease can be attributed to mental illness. Despite important advances in identifying risk factors for mental health conditions, the biological processing underlying causal pathways to disease onset r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430533de7324e45a23d75a3375e6d1e8
https://hdl.handle.net/10668/22575
https://hdl.handle.net/10668/22575
Autor:
Greg Pasco, Emma L. Meaburn, Anna Gui, X. Baocong, Emily J.H. Jones, Mark H. Johnson, Chloe C. Y. Wong, Sarah Lloyd-Fox, Tony Charman, Patrick Bolton
Publikováno v:
Infant Behavior and Development
Preliminary evidence suggests that changes in DNA methylation, a widely studied epigenetic mechanism, contribute to the etiology of Autism Spectrum Disorder (ASD). However, data is primarily derived from post-mortem brain samples or peripheral tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1625fdb140100c2a3eb2ebc597892c
https://eprints.bbk.ac.uk/id/eprint/30313/10/30313a.pdf
https://eprints.bbk.ac.uk/id/eprint/30313/10/30313a.pdf