Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chloe A. Simons"'
Autor:
Kelly M. Flounlacker, Yun Kyung Hahn, Ruqiang Xu, Chloe A. Simons, Tao Tian, Kurt F. Hauser, Pamela E. Knapp
Publikováno v:
Journal of NeuroVirology. 29:15-26
Autor:
Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, András Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar
Publikováno v:
eLife, Vol 10 (2021)
Controlling receptor functional selectivity profiles for opioid receptors is a promising approach for discovering safer analgesics; however, the structural determinants conferring functional selectivity are not well understood. Here, we used crystal
Externí odkaz:
https://doaj.org/article/dc31183697a3454e95268139bbe3d9fd
Autor:
Vinicius Duarte, Jay P. McLaughlin, Olivia Wallman, Chloe A. Simons, Amy R. Alleyne, Jessica M. Medina, Justin Kendrick, Emet M. Anceaume, Heather M. Stacy, Shainnel O. Eans, Ariana M Figueroa, Thomas J. Cirino
Publikováno v:
Journal of Neuroimmune Pharmacology. 17:152-164
Despite the success of combined antiretroviral therapy (cART) in reducing viral load, a substantial portion of Human Immunodeficiency Virus (HIV)+ patients report chronic pain. The exact mechanism underlying this co-morbidity even with undetectable v
Autor:
Heather M. Stacy, Susruta Majumdar, Soumen Chakraborty, Jay P. McLaughlin, Lisa L. Wilson, Rajendra Uprety, Chloe A. Simons, Shainnel O. Eans, Thomas J. Cirino
Publikováno v:
Cell Mol Neurobiol
Chronic administration of opioids produces physical dependence and opioid-induced hyperalgesia. Users claim the Thai traditional tea “Kratom” and component alkaloid mitragynine ameliorate opioid withdrawal without increased sensitivity to pain. T
Autor:
Samuel T. Slocum, Vsevolod Katritch, Rajendra Uprety, Joan J. Subrath, Jay P. McLaughlin, Gavril W. Pasternak, Ying Xian Pan, Amanda Hunkele, Valerie Le Rouzic, Melissa Nelson, Steven G. Grinnell, Abdelfattah Faouzi, András Váradi, Saheem A. Zaidi, Bryan L. Roth, Shainnel O. Eans, Balázs Varga, Elizaveta Kulko, Abdullah Allaoa, Tao Che, Susruta Majumdar, Sarah M Bernhard, Jonathan A. Javitch, Chloe A. Simons
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Controlling receptor functional selectivity profiles for opioid receptors is a promising approach for discovering safer analgesics; however, the structural determinants conferring functional selectivity are not well understood. Here, we used crystal
Autor:
Gavril W. Pasternak, Abdelfattah Faouzi, Bryan L. Roth, Amanda Hunkele, Steven G. Grinnell, Susruta Majumdar, Valerie Le Rouzic, Melissa Nelson, Sarah M Bernhard, Chloe A. Simons, Shainnel O. Eans, Samuel T. Slocum, Rajendra Uprety, Joan J. Subrath, András Váradi, Tao Che, Ying Xian Pan, Jonathan A. Javitch, Elizaveta Kulko, Vsevolod Katritch, Abdullah Allaoa, Saheem A. Zaidi, Balázs Varga, Jay P. McLaughlin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acf306e63c447f91f658560d8a55c64b
https://doi.org/10.7554/elife.56519.sa2
https://doi.org/10.7554/elife.56519.sa2
Autor:
Chloe A. Simons, Michael J. Ferracane, Jeremy S. Coleman, Jay P. McLaughlin, Jane V. Aldrich, Ariana C. Brice-Tutt, Heather M. Stacy, Lisa L. Wilson, Grant G. Simpson, Shainnel O. Eans
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: The macrocyclic tetrapeptide natural product CJ‐15,208 (cyclo[Phe‐d‐Pro‐Phe‐Trp]) is a multifunctional μ‐opioid receptor and κ‐opioid receptor agonist and κ‐opioid receptor antagonist that produces antinocic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fe153a942f68226d86b685201a7f1b
https://europepmc.org/articles/PMC7443475/
https://europepmc.org/articles/PMC7443475/
Autor:
Thomas J, Cirino, Amy R, Alleyne, Vinicius, Duarte, Ariana, Figueroa, Chloe A, Simons, Emet M, Anceaume, Justin, Kendrick, Olivia, Wallman, Shainnel O, Eans, Heather M, Stacy, Jessica M, Medina, Jay P, McLaughlin
Publikováno v:
J Neuroimmune Pharmacol
BACKGROUND: Despite the success of combined antiretroviral therapy (cART) in reducing viral load, a substantial portion of Human Immunodeficiency Virus (HIV)+ patients report chronic pain. The exact mechanism underlying this co-morbidity even with un
Autor:
Jay P. McLaughlin, Bonnie A. Avery, Hannah M. Harris, Lisa L. Wilson, Ariana C. Brice-Tutt, Abhisheak Sharma, Heather M. Stacy, Shainnel O. Eans, Thomas J. Cirino, Edward W. Boyer, Chloe A. Simons, Francisco León, Christopher R. McCurdy
Publikováno v:
Drug and Alcohol Dependence. 216:108310
Background Made as a tea, the Thai traditional drug “kratom” reportedly possesses pharmacological actions that include both a coca-like stimulant effect and opium-like depressant effect. Kratom has been used as a substitute for opium in physicall
Autor:
Tao Che, Saheem A. Zaidi, Jay P. McLaughlin, Chloe A. Simons, Abdelfattah Faouzi, Susruta Majumdar, Ivy F Carroll, Manish K. Madasu, Ying-Xian Pan, Tiffany Zhang, Vsevolod Katritch, Chad Kormos, Bryan L. Roth, Shainnel O. Eans, Ream Al Hassani
Publikováno v:
The FASEB Journal. 34:1-1