Validation of metaxin-2 deficient C. elegans as a model for MandibuloAcral Dysplasia associated to mtx-2 (MADaM) syndrome

Autor: Chloé Talarmin-Gas, Georges Smolyakov, Cleo Parisi, Cyril Scandola, Valérie Andrianasolonirina, Cloé Lecoq, Valentine Houtart, Song-Hua Lee, Homa Adle-Biassette, Bénédicte Thiébot, Timothy Ganderton, Philippe Manivet

Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)

Abstract MandibuloAcral Dysplasia associated to MTX2 gene (MADaM) is a recently described progeroid syndrome (accelerated aging disease) whose clinical manifestations include skin abnormalities, growth retardation, and cardiovascular diseases. We pre

Externí odkaz: https://doaj.org/article/1dbb1081659043f4b03a5d849a79099d

Quality risk management of the chimeric antigen receptor T cell pharmaceutical circuit in one of the first qualified European centers

Autor: Eden Schwartz, Nicolas Boissel, Anne Brignier, Isabelle Madelaine, Nathalie Parquet, André Desproges, Sarah Mukenyi, Lorène Magdelonnette, Chloé Talarmin, Emmanuelle Lesprit, André Baruchel, Catherine Thieblemont, Steven Kerob, Jérôme Larghero, Miryam Mebarki, François Cartier

Publikováno v: Cytotherapy
Cytotherapy, Elsevier, 2020, 22, pp.792-801. ⟨10.1016/j.jcyt.2020.06.009⟩
Cytotherapy, 2020, 22, pp.792-801. ⟨10.1016/j.jcyt.2020.06.009⟩

International audience; Background aims: According to European Directive 2001/83/EC, chimeric antigen receptor T (CAR T) cells belong to a new class of medicines referred to as advanced therapy medicinal products (ATMPs). The specific features and co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2314eace724f4eff1791a6601f770943
https://pubmed.ncbi.nlm.nih.gov/32732084