Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chloé Roffay"'
Autor:
Lea Assies, José García-Calvo, Francesca Piazzolla, Samantha Sanchez, Takehiro Kato, Luc Reymond, Antoine Goujon, Adai Colom, Javier López-Andarias, Karolína Straková, Dora Mahecic, Vincent Mercier, Margot Riggi, Noemi Jiménez-Rojo, Chloé Roffay, Giuseppe Licari, Maria Tsemperouli, Frederik Neuhaus, Alexandre Fürstenberg, Eric Vauthey, Sascha Hoogendoorn, Marcos Gonzalez-Gaitan, Andreas Zumbuehl, Kaori Sugihara, Jean Gruenberg, Howard Riezman, Robbie Loewith, Suliana Manley, Aurelien Roux, Nicolas Winssinger, Naomi Sakai, Stefan Pitsch, Stefan Matile
Publikováno v:
CHIMIA, Vol 75, Iss 12 (2021)
This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR©, ER Fl
Externí odkaz:
https://doaj.org/article/bc42a5ddeb734d338971c739fd7fea45
Autor:
José García-Calvo, Javier López-Andarias, Jimmy Maillard, Vincent Mercier, Chloé Roffay, Aurélien Roux, Alexandre Fürstenberg, Naomi Sakai, Stefan Matile
Publikováno v:
Chemical science, Vol. 13, No 7 (2022) pp. 2086-2093
HydroFlippers are introduced as the first fluorescent membrane tension probes that report simultaneously on membrane compression and hydration. The probe design is centered around a sensing cycle that couples the mechanical planarization of twisted p
Autor:
Chloé Roffay, Juan Manuel García-Arcos, Pierrik Chapuis, Javier López-Andarias, Falk Schneider, Adai Colom, Caterina Tomba, Ilaria Di Meglio, Valentin Dunsig, Stefan Matile, Aurélien Roux, Vincent Mercier
Measuring forces within living cells remains a technical challenge. We developed hydrophobic mechanosensing fluorescent probes called Flippers, whose fluorescence lifetime depends on lipid packing and can report on membrane tension. Here, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5955a207fb895f20afe5456742d01935
https://doi.org/10.1101/2022.09.28.509885
https://doi.org/10.1101/2022.09.28.509885
Autor:
Aurélien Roux, José García-Calvo, Martin Lenz, Vincent Mercier, Guillaume Molinard, Kyoohyun Kim, Jochen Guck, Chloé Roffay, Stefan Matile, Marta Urbanska, Victoria Barbarassa
During osmotic changes of their environment, cells actively regulate their volume and plasma membrane tension that can passively change through osmosis. How tension and volume are coupled during osmotic adaptation remains unknown, as a quantitative c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7657e40643c60a386aa35c6580c26cc
https://doi.org/10.1101/2021.01.22.427801
https://doi.org/10.1101/2021.01.22.427801
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2021, 148 (18), pp.dev192773. ⟨10.1242/dev.192773⟩
Development (Cambridge, England), 2021, 148 (18), pp.dev192773. ⟨10.1242/dev.192773⟩
Development
Development (Cambridge, England), Company of Biologists, 2021, 148 (18), pp.dev192773. ⟨10.1242/dev.192773⟩
Development (Cambridge, England), 2021, 148 (18), pp.dev192773. ⟨10.1242/dev.192773⟩
Development
Recognizing the crucial role of mechanical regulation and forces in tissue development and homeostasis has stirred a demand for in situ measurement of forces and stresses. Among emerging techniques, the use of cell geometry to infer cell junction ten
Autor:
Stefan Matile, Vincent Mercier, Robbie Loewith, Aurélien Roux, Martin Lenz, Paulina Nowak, Arnaud Echard, Guillaume Molinard, Chloé Roffay, Victoria Barbarasa, Kyoohyun Kim, José García-Calvo, Marta Urbanska, Virginia Andrade, Jochen Guck
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (47), pp.e2103228118. ⟨10.1073/pnas.2103228118⟩
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No 47 (2021) P. e2103228118
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (47), pp.e2103228118. ⟨10.1073/pnas.2103228118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (47), pp.e2103228118. ⟨10.1073/pnas.2103228118⟩
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No 47 (2021) P. e2103228118
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (47), pp.e2103228118. ⟨10.1073/pnas.2103228118⟩
Significance Tension is the force-opposing stretch of lipid membranes. It controls cell functions involving membranes. Membranes rupture above a tension threshold, causing cell death if tension is not properly buffered. However, how cell membrane ten