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pro vyhledávání: '"Chloé Philippe"'
Autor:
Chloé Philippe, Benoît Pinson, Jim Dompierre, Véronique Pantesco, Benoît Viollet, Bertrand Daignan-Fornier, Michel Moenner
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 6, Pp 555-562 (2018)
AICAR (Acadesine) is a pharmacological precursor of purine nucleotide biosynthesis with anti-tumoral properties. Although recognized as an AMP mimetic activator of the protein kinase AMPK, the AICAR monophosphate derivative ZMP was also shown to medi
Externí odkaz:
https://doaj.org/article/f8b13ada0770436c8378f60106b2ad78
Autor:
Chloé Philippe, Jean Laporte, Michel Moenner, Bertrand Daignan-Fornier, Adrien Labriet, Benoît Pinson, Christelle Saint-Marc, Johanna Ceschin
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (24), pp.16844-16854. ⟨10.1074/jbc.M114.551192⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (24), pp.16844-16854. ⟨10.1074/jbc.M114.551192⟩
5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAr) is the precursor of the active monophosphate form (AICAR), a small molecule with potent anti-proliferative and low energy mimetic properties. The molecular bases for AICAR toxicity at the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2ed6a06524c3bd6d93094fb0c9e319
https://pubmed.ncbi.nlm.nih.gov/24778186
https://pubmed.ncbi.nlm.nih.gov/24778186