Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chloé Martens"'
Autor:
Julija Armalytė, Albinas Čepauskas, Gabija Šakalytė, Julius Martinkus, Jūratė Skerniškytė, Chloé Martens, Edita Sužiedėlienė, Abel Garcia-Pino, Dukas Jurėnas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Acinetobacter baumannii is a nosocomial pathogen highly resistant to environmental changes and antimicrobial treatments. Regulation of cellular motility and biofilm formation is important for its virulence, although it is poorly described at
Externí odkaz:
https://doaj.org/article/f5b7dfe3d72c46cdbc600122d8062341
Autor:
Daniel, Scholl, Maud, Sigoillot, Marie, Overtus, Rafael Colomer, Martinez, Chloé, Martens, Yiting, Wang, Els, Pardon, Toon, Laeremans, Abel, Garcia-Pino, Jan, Steyaert, David N, Sheppard, Jelle, Hendrix, Cédric, Govaerts
Publikováno v:
Nature chemical biology. 17(9)
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel is essential to maintain fluid homeostasis in key organs. Functional impairment of CFTR due to mutations in the cftr gene leads to cystic fibrosis. Here, we show that the fi
Autor:
Ruyu Jia, Chloe Martens, Mrinal Shekhar, Shashank Pant, Grant A. Pellowe, Andy M. Lau, Heather E. Findlay, Nicola J. Harris, Emad Tajkhorshid, Paula J. Booth, Argyris Politis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
XylE is a bacterial xylose transporter and homologue of human glucose transporters GLUTs 1-4. HDX-MS, mutagenesis and MD simulations suggest that protonation of a conserved aspartate triggers conformational transition from outward- to inward facing s
Externí odkaz:
https://doaj.org/article/d6cb78ca4eb8432388486c3f0d334672
Autor:
Sarah V. Faull, Andy M. C. Lau, Chloe Martens, Zainab Ahdash, Kjetil Hansen, Hugo Yebenes, Carla Schmidt, Fabienne Beuron, Nora B. Cronin, Edward P. Morris, Argyris Politis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The COP9 signalosome (CSN) regulates Cullin-RING Ligase 2 (CRL2) but the molecular basis for their interaction is unknown. Here the authors use structural mass spectrometry and cryo-EM approaches to assess the structures and dynamics of CSN-CRL2 comp
Externí odkaz:
https://doaj.org/article/763dbdaeaef24615aa8b9632161a84b5
Autor:
Chloe Martens, Mrinal Shekhar, Antoni J. Borysik, Andy M. Lau, Eamonn Reading, Emad Tajkhorshid, Paula J. Booth, Argyris Politis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Secondary transporters catalyse substrate translocation across the cell membrane but the role of lipids during the transport cycle remains unclear. Here authors used hydrogen-deuterium exchange mass spectrometry and molecular dynamics simulations to
Externí odkaz:
https://doaj.org/article/3878486fe69c4a06a829c58c6f048e54