Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chloé I. Charendoff"'
Autor:
Dharaniya Sakthivel, Alexandra N. Brown-Suedel, Francesca Keane, Shixia Huang, Kenneth Mc Sherry, Chloé I Charendoff, Kevin P. Dunne, Dexter J Robichaux, BaoChau Le, Crystal S. Shin, Alexandre F Carisey, Jonathan M. Flanagan, Lisa Bouchier-Hayes
Publikováno v:
bioRxiv
Mutation in nucleophosmin (NPM1) causes relocalization of this normally nucleolar protein to the cytoplasm (NPM1c+). Despite NPM1 mutation being the most common driver mutation in cytogenetically normal adult acute myeloid leukemia (AML), the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068057070548de56646af1a6eb36ab5b
https://doi.org/10.1101/2023.05.29.542723
https://doi.org/10.1101/2023.05.29.542723
Autor:
Chloé I. Charendoff, Agathe Subtil, Shir Marciano, Debabrata Dey, Jiří Zahradník, Gideon Schreiber, Lucie Kolářová
Publikováno v:
ACS Synthetic Biology
ACS Synthetic Biology, 2021, 10 (12), pp.3445-3460. ⟨10.1021/acssynbio.1c00395⟩
ACS Synthetic Biology, 2021, 10 (12), pp.3445-3460. ⟨10.1021/acssynbio.1c00395⟩
International audience; Here, we enhanced the popular yeast display method by multiple rounds of DNA and protein engineering. We introduced surface exposure-tailored reporters, eUnaG2 and DnbALFA, creating a new platform of C and N terminal fusion ve
Autor:
Vijay Charaka, Alexandre F. Carisey, Ashley Boice, Raj K. Pandita, Tej K. Pandita, Lisa Bouchier-Hayes, Karla E. Lopez, Melissa J. Parsons, Chloé I. Charendoff
Publikováno v:
Oncogene. 41:204-219
In addition to its classical role in apoptosis, accumulating evidence suggests that caspase-2 has non-apoptotic functions, including regulation of cell division. Loss of caspase-2 is known to increase proliferation rates but how caspase-2 is regulati
Autor:
Ashley Boice, Tej K. Pandita, Vijay Charaka, Melissa J. Parsons, Lisa Bouchier-Hayes, Karla E. Lopez, Raj K. Pandita, Alexandre F. Carisey, Chloé I. Charendoff
In addition to its classical role in apoptosis, accumulating evidence suggests that caspase-2 has non-apoptotic functions, including regulation of cell division. Loss of caspase-2 is known to increase proliferation rates but how caspase-2 is regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a8919ecab2a9990d3a0b4baf99e8415
https://doi.org/10.1101/2021.03.30.437768
https://doi.org/10.1101/2021.03.30.437768
Autor:
Alexandra N Brown-Suedel, Vanda Yazdani, Chloé I. Charendoff, Jonathan M. Flanagan, Gregory M. Vercellotti, Lisa Bouchier-Hayes, Beatriz E. Bolívar, Brittany A. Rohrman, John D. Belcher
Publikováno v:
J Immunol
Excessive release of heme from RBCs is a key pathophysiological feature of several disease states, including bacterial sepsis, malaria, and sickle cell disease. This hemolysis results in an increased level of free heme that has been implicated in the
Autor:
Chloé I. Charendoff, John D. Belcher, Vanda Yazdani, Brittany A. Rohrman, Jonathan M. Flanagan, Gregory M. Vercellotti, Beatriz E. Bolívar, Lisa Bouchier-Hayes
Excessive release of heme from red blood cells is a key pathophysiological feature of several disease states including bacterial sepsis, malaria, and sickle cell disease. This hemolysis results in an increased level of free heme that has been implica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8dc37ff4511a253ed29f90a2057d2a
Autor:
Kiyohiro Ando, Sara R. Fassio, Ruth Thompson, Sheré L. Paris, Andrew Oberst, Brittany A. Rohrman, Peter H. Liu, Richa B. Shah, Chloé I. Charendoff, Lisa Bouchier-Hayes, Melissa J. Parsons, Samuel Sidi
Publikováno v:
Journal of Cell Biology. 216:1795-1810
The PIDDosome (PIDD–RAIDD–caspase-2 complex) is considered to be the primary signaling platform for caspase-2 activation in response to genotoxic stress. Yet studies of PIDD-deficient mice show that caspase-2 activation can proceed in the absence
Publikováno v:
Journal of Visualized Experiments.
The caspase family of proteases play essential roles in apoptosis and innate immunity. Among these, a subgroup known as initiator caspases are the first to be activated in these pathways. This group includes caspase-2, -8, and -9, as well as the infl