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Akademický článek

Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts

Autor: Amrutha Kizhedathu, Rose Sebastian Kunnappallil, Archit V Bagul, Puja Verma, Arjun Guha

Publikováno v: eLife, Vol 9 (2020)

Larval tracheae of Drosophila harbour progenitors of the adult tracheal system (tracheoblasts). Thoracic tracheoblasts are arrested in the G2 phase of the cell cycle in an ATR (mei-41)-Checkpoint Kinase1 (grapes, Chk1) dependent manner prior to mitot

Externí odkaz: https://doaj.org/article/7e3c089b5c734fef87795d62bb367fc7

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Akademický článek

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Author response: Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts

Autor: Rose Sebastian Kunnappallil, Archit V Bagul, Arjun Guha, Puja Verma, Amrutha Kizhedathu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62d85d2b422c417c318121612c6f4100
https://doi.org/10.7554/elife.57056.sa2

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Decision letter: Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts

Autor: Greg J. Beitel, Bruce Edgar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::719f7bb16d80af512b2eba31ce1d153f
https://doi.org/10.7554/elife.57056.sa1

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Akademický článek

Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts

Autor: Amrutha Kizhedathu, Piyush Chhajed, Lahari Yeramala, Deblina Sain Basu, Tina Mukherjee, Kutti R Vinothkumar, Arjun Guha

Publikováno v: eLife, Vol 10 (2021)

Progenitors of the thoracic tracheal system of adult Drosophila (tracheoblasts) arrest in G2 during larval life and rekindle a mitotic program subsequently. G2 arrest is dependent on ataxia telangiectasia mutated and rad3-related kinase (ATR)-depende

Externí odkaz: https://doaj.org/article/c6a6fa25a40c4c62b5490fb4d24957bd

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Akademický článek

Negative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates tracheoblast growth and tracheal hypertrophy in Drosophila

Autor: Amrutha Kizhedathu, Archit V Bagul, Arjun Guha

Publikováno v: eLife, Vol 7 (2018)

Imaginal progenitors in Drosophila are known to arrest in G2 during larval stages and proliferate thereafter. Here we investigate the mechanism and implications of G2 arrest in progenitors of the adult thoracic tracheal epithelium (tracheoblasts). We

Externí odkaz: https://doaj.org/article/777d6731a382485ebe72c904c2fbe6e2

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