Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Chizuru, Ito"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Normal sperm flagellar shape and movement are essential for fertilization. The integral protein outer dense fiber 4 (ODF4) localizes to ODFs, but its function remains unclear. Adenylate kinase (AK) is a phosphotransferase that catalyzes the
Externí odkaz:
https://doaj.org/article/4cfb919dc61b40e3b8db1ab2dd4499d1
Autor:
Cheng Chen, Mamiko Maekawa, Kenji Yamatoya, Masami Nozaki, Chizuru Ito, Toshihiko Iwanaga, Kiyotaka Toshimori
Publikováno v:
Asian Journal of Andrology, Vol 18, Iss 4, Pp 600-606 (2016)
Basigin is a member of the immunoglobulin superfamily and plays various important roles in biological events including spermatogenesis. To examine the basigin molecular variants during spermatogenesis and sperm maturation in the mouse, immunoprecipit
Externí odkaz:
https://doaj.org/article/3be127aebcdc4e1da53eae84d4f69961
Autor:
Takahiro Yamagata, Hideo Dohra, Wataru Fujii, Keiichiro Yogo, Mamoru Nagano, Kiyotaka Toshimori, Yu Okitsu, Chizuru Ito
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Deleted in lung and esophageal cancer 1 (DLEC1) is a tumour suppressor gene that is downregulated in various cancers in humans; however, the physiological and molecular functions of DLEC1 are still unclear. This study investigated the critical role o
Autor:
Masahiko Hatano, Kiyotaka Toshimori, Marika Kousaka, Yoshihiko Araki, Chizuru Ito, Kenji Yamatoya, Kazuya Nakata
Publikováno v:
Biology of Reproduction. 102:750-757
The acrosome reaction is a multi-step event essential for physiological fertilization. During the acrosome reaction, gamete fusion-related factor IZUMO1 translocates from the anterior acrosome to the equatorial segment and assembles the gamete fusion
Autor:
Masaaki Ohmori, Masahiko Hatano, Naruhiko Ishiwada, Haruka Hishiki, Rintaro Nishimura, Chizuru Ito, Eizo Watanabe, Toshinobu Akamatsu, Lisa Fujimura, Noriko Takeuchi, Mayu Kato
Publikováno v:
Cytokine. 149
Purpose The anticoagulant agent recombinant thrombomodulin (rTM) activates protein C to prevent excessive coagulation and also possibly regulates hyper-inflammation via neutralization of high-mobility-group B1 (HMG-B1). The glycocalyx layer in endoth
Autor:
Yumi Mizuno, Yuichi Ninomiya, Yutaka Nakachi, Mioko Iseki, Hiroyasu Iwasa, Masumi Akita, Tohru Tsukui, Nobuyuki Shimozawa, Chizuru Ito, Kiyotaka Toshimori, Megumi Nishimukai, Hiroshi Hara, Ryouta Maeba, Tomoki Okazaki, Ali Nasser Ali Alodaib, Mohammed Al Amoudi, Minnie Jacob, Fowzan S Alkuraya, Yasushi Horai, Mitsuhiro Watanabe, Hiromi Motegi, Shigeharu Wakana, Tetsuo Noda, Igor V Kurochkin, Yosuke Mizuno, Christian Schönbach, Yasushi Okazaki
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003286 (2013)
Peroxisomes are subcellular organelles involved in lipid metabolic processes, including those of very-long-chain fatty acids and branched-chain fatty acids, among others. Peroxisome matrix proteins are synthesized in the cytoplasm. Targeting signals
Externí odkaz:
https://doaj.org/article/7c0fcabd2f8148dfb02c972a9f888031
Autor:
Chizuru Ito, Kenichiro Hiraoka, Megumi Ibayashi, Takashi Nakasuji, Kiyotaka Kawai, Tatsuya Harada, Tohru Mutoh, Takayuki Tatsumi, Akira Komiya, Masato Saito
Publikováno v:
Transl Androl Urol
A husband and his wife, both 34 years old, consulted our clinic because of primary infertility. Sperm analysis revealed that the sperm concentration, motility, and progressive motility were (42.8±22.8)×10(6)/mL, 23.3%±12.2%, and 12.9%±6.1%, respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd55027525c4208c4e3851303c6969c1
https://europepmc.org/articles/PMC7215008/
https://europepmc.org/articles/PMC7215008/
Autor:
Atsushi Kasamatsu, Tomoaki Saito, Katsuhiro Uzawa, Yasuhiko Okubo, Mitsuo Yamauchi, Chizuru Ito, Masataka Sunohara, Hideki Tanzawa, Fumihiko Hayashi, Sachi Oshima, Kiyotaka Toshimori, Masahiko Terajima, Yuki Taga
Publikováno v:
Bone. 154:116242
Lysyl hydroxylase 2 (LH2) is an enzyme that catalyzes the hydroxylation of lysine (Lys) residues in fibrillar collagen telopeptides, a critical post-translational modification for the stability of intermolecular cross-links. Though abnormal LH2 activ
Autor:
Takehiko Oami, Lisa Fujimura, Eizo Watanabe, Shigeto Oda, Paul E. Swanson, Kiyotaka Toshimori, Akemi Sakamoto, Youichi Teratake, Chizuru Ito, Masahiko Hatano
Publikováno v:
Shock. 50:427-434
Autophagy plays an important role in cell survival, sequestering, and degrading a wide variety of substrates. Although an increase of autophagosomes in liver has been reported in sepsis patients as well as in septic mice, the influence of autophagy o
Autor:
Katsuyuki Nagata, Tadashi Okamura, Yoshiko Iizuka-Hishikawa, Kiyotaka Toshimori, Keiyo Takubo, Takehiko Sasaki, Chizuru Ito, Takao Shimizu, Junko Sasaki, Hiroki Nakanishi, Motohito Goto, Daisuke Hishikawa, Hideo Shindou
Publikováno v:
The Journal of Biological Chemistry
Docosahexaenoic acid (DHA) is one of the essential ω-3 polyunsaturated fatty acids with a wide range of physiological roles important for human health. For example, DHA renders cell membranes more flexible and is therefore important for cellular fun