Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Chizu Ishii"'
Publikováno v:
Fungal Genetics and Biology. 47:809-817
Genome integrity is maintained by many cellular mechanisms in eukaryotes. One such mechanism functions during the cell cycle and is known as the DNA damage checkpoint. In the filamentous fungus Neurospora crassa, mus-9 and mus-21 are homologes of two
Publikováno v:
Biochemical and Biophysical Research Communications. 396:289-293
Gene targeting induced by homologous integration of a foreign DNA segment into a chromosomal target sequence enables precise disruption or replacement of genes of interest and provides an effective means to analyze gene function, and also becomes an
Publikováno v:
DNA Repair. 7:1951-1961
DNA damage checkpoint is an important mechanism for organisms to maintain genome integrity. In Neurospora crassa, mus-9 and mus-21 are homologues of ATR and ATM, respectively, which are pivotal factors of DNA damage checkpoint in mammals. A N. crassa
Autor:
Michiyoshi Wakabayashi, Alice L. Schroeder, Yusuke Kazama, Hirokazu Inoue, Hisao Shimada, Chizu Ishii
Publikováno v:
DNA Repair. 7:213-229
The mutagen sensitive uvs-3 and mus-9 mutants of Neurospora show mutagen and hydroxyurea sensitivity, mutator effects and duplication instability typical of recombination repair and DNA damage checkpoint defective mutants. To determine the nature of
Publikováno v:
Journal of General Plant Pathology. 72:16-19
The first two recombinational repair genes of Magnaporthe grisea were cloned. Analysis of the deduced amino acid sequences revealed that Rhm52 and Rhm54 are Saccharomyces cerevisiae RAD52 and RAD54 homologs, respectively. Phenotypic complementation t
Publikováno v:
Proceedings of the National Academy of Sciences. 101:12248-12253
Gene disruption and overexpression play central roles in the analysis of gene function. Homologous recombination is, in principle, the most efficient method of disrupting, modifying, or replacing a target gene. Although homologous integration of exog
Publikováno v:
DNA Repair. 2:337-346
In a previous paper, we reported that the Neurospora crassa upr-1 gene is a homolog of the yeast gene REV3, which encodes the catalytic subunit of DNA polymerase zeta (polzeta). Characterization of the upr-1 mutant indicated that the UPR1 protein pla
Publikováno v:
ResearcherID
We isolated a Neurospora crassa cDNA that encodes a Rad52 homologue (ncRAD52) by PCR, using degenerate primers. RFLP mapping demonstrated that the cloned gene is located close to the ro-4 locus on the right arm of linkage group V (LGVR). In a second
Variation of spontaneous somatic mutation frequency in the stamen hairs of Tradescantia clone BNL 02
Autor:
Naoko Shima, Sadao Ichikawa, Chie Matsuura-Endo, Marie Sanda-Kamigawara, Hiromi Kanai, Chizu Ishii
Publikováno v:
GENES & GENETIC SYSTEMS. 71(3):159-165
Variation of spontaneous somatic mutation frequency was studied in the stamen hairs of Tradescantia clone BNL 02 heterozygous for flower color (blue/pink; the blue color being dominant), one of the most stable clones in terms of spontaneous mutation
Autor:
Jihe Zhao, Masashi Takao, Chizu Ishii, Shinji Yasuhira, Hirokazu Inoue, Hirohiko Yajima, Akira Yasui
Publikováno v:
The EMBO Journal. 14:2393-2399
Many eukaryotic organisms, including humans, remove ultraviolet (UV) damage from their genomes by the nucleotide excision repair pathway, which requires more than 10 separate protein factors. However, no nucleotide excision repair pathway has been fo