Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chizu, Fujimura"'
Autor:
Shinichi Sato, Shogo Miyano, Keita Nakane, Zhengyi Liu, Munehiro Kumashiro, Tomohide Saio, Yuya Tanaka, Akira Shigenaga, Chizu Fujimura, Eri Koyanagi, Hafumi Nishi, Shusuke Tomoshige, Minoru Ishikawa
Publikováno v:
Tetrahedron Chem, Vol 12, Iss , Pp 100111- (2024)
Our ex situ tyrosine bioconjugation method utilizes the oxidation of N-methylurazole by Bobbitt's salt or electrochemical activation to generate stable radicals for selective tyrosine labeling, thereby addressing the longstanding challenges in protei
Externí odkaz:
https://doaj.org/article/a0400cbecd224dc386991e75fa935f8a
Autor:
Keita Nakane, Haruto Nagasawa, Chizu Fujimura, Eri Koyanagi, Shusuke Tomoshige, Minoru Ishikawa, Shinichi Sato
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11622
Weak and transient protein interactions are involved in dynamic biological responses and are an important research subject; however, methods to elucidate such interactions are lacking. Proximity labeling is a promising technique for labeling transien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9ecdcb0763d97a2985401d21ac4f21
Publikováno v:
Archives of Toxicology. 95:2755-2768
We have reported that the IL-2 Luc assay can detect the effects of chemicals on IL-2 promoter activity by using a dual reporter cell line, 2H4 cells that measure IL-2 promoter-driven luciferase activity (IL2LA) and GAPDH promoter-driven luciferase ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5559b380a27af9417dacf2b573b73663
https://doi.org/10.1007/s00204-021-03101-4
https://doi.org/10.1007/s00204-021-03101-4
Publikováno v:
Archives of Toxicology. 95:1647-1657
IL-1 functions as an essential pro-inflammatory mediator for the sensitisation of allergic contact dermatitis (ACD). However, studies conducted to date have typically used a limited number of haptens and examined their effects only on murine ACD or m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae8b5661c2125b04c2f39c7099d18a4
https://doi.org/10.1007/s00204-021-03022-2
https://doi.org/10.1007/s00204-021-03022-2
Publikováno v:
Archives of Toxicology. 95:749-758
False-negative judgment due to poor chemical solubility is a problem with in vitro skin sensitisation tests. Water-insoluble chemicals are typically dissolved in DMSO in most sensitisation tests but precipitate when diluted with medium beyond their s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75012113aa64db6289d997b186667245
https://doi.org/10.1007/s00204-020-02934-9
https://doi.org/10.1007/s00204-020-02934-9
Autor:
Kimura, Yutaka, Yasuno, Rie, Tomoko, Iwaki, Chizu, Fujimura, Yoshihiro, Ohmiya, Yoshihiro, Nakajima, Takashi, Omori, Emanuela, Corsini, Tomoaki, Inoue, Erwin L, Rogen, Hajime, Kojima, Setsuya, Aiba
Publikováno v:
Toxicology in Vitro. 88:105535
We previously reported that the IL-2 Luc LTT can detect immunosuppressive effects of drugs that are attributed to their antimitotic activity. Here, we report an official validation study of the IL-2 Luc LTT. In the Phase I study that evaluated five c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91f412a4087da256cd0a10dff85b4dd
https://doi.org/10.1016/j.tiv.2022.105535
https://doi.org/10.1016/j.tiv.2022.105535
Autor:
Yutaka Kimura1, Chizu Fujimura1, Toshifumi Imagawa2, Lupisan, Socorro P.3, Mariko Saito- Obata2, Mayuko Saito2, Hitoshi Oshitani2, Setsuya Aiba1 saiba@med.tohoku.ac.jp
Publikováno v:
EXCLI Journal. 2020, Vol. 19, p1054-1063. 10p.
Autor:
Sato Shinichi, Satsuki Obara, Chizu Fujimura, Shusuke Tomoshige, Minoru Ishikawa, Keita Nakane
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8676, p 8676 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8676, p 8676 (2021)
Human serum albumin (HSA) is a promising drug delivery carrier. Although covalent modification of Cys34 is a well-established method, it is desirable to develop a novel covalent modification method that targets residues other than cysteine to introdu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451023518fa75d557775906c28d43f7c
http://europepmc.org/articles/PMC8395410
http://europepmc.org/articles/PMC8395410
Publikováno v:
Archives of toxicology. 95(2)
False-negative judgment due to poor chemical solubility is a problem with in vitro skin sensitisation tests. Water-insoluble chemicals are typically dissolved in DMSO in most sensitisation tests but precipitate when diluted with medium beyond their s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe18829f54232f5cd065f6b064018460
https://pubmed.ncbi.nlm.nih.gov/33068120
https://pubmed.ncbi.nlm.nih.gov/33068120
Publikováno v:
Archives of Toxicology. 92:2043-2054
We established a luciferase reporter assay system, the Multi-ImmunoTox Assay (MITA), which can evaluate the effects of chemicals on the promoter activities of four cytokines: IL-2, IFN-γ, IL-1β, and IL-8. We previously reported that MITA correctly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db07a011e08e8fa21f30e3b435283a0
https://doi.org/10.1007/s00204-018-2199-7
https://doi.org/10.1007/s00204-018-2199-7