Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chiu Cheong Aw"'
Autor:
Yuan-Kun Lee, Yi Shuen Hong, Eleanor Jing Yi Cheong, Edward R. Browne, Eric Chun Yong Chan, Han Chen Ku, Niranjan Nagarajan, Amanda Hui Qi Ng, Lian Yee Yip, Sze Han Lee, Chiu Cheong Aw, Jessalyn Mei Xuan Chan, Ratha Mahendran, Kern Rei Chng, Winston Hecheng Xu
Publikováno v:
Hepatology (Baltimore, Md.). 67(1)
The gut microbiota possesses diverse metabolic activities but its contribution towards heterogeneous toxicological responses is poorly understood. Here, we elucidate the role of the liver-gut microbiota axis in underpinning the hepatotoxicity of tacr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edda33dc55c019732979f4c5c31b6d0
https://pubmed.ncbi.nlm.nih.gov/28782199
https://pubmed.ncbi.nlm.nih.gov/28782199
Publikováno v:
Drug Metabolism and Disposition. 39:402-411
Physiological alterations that may change pharmacological response accompany aging. Pharmacokinetic/pharmacodynamic properties of cholinesterase inhibitors (ChEIs) used in the treatment of Alzheimer's disease, donepezil, tacrine, and galantamine, wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57892ed51050f3310f424426cb373031
https://doi.org/10.1124/dmd.110.035964
https://doi.org/10.1124/dmd.110.035964
Autor:
Zeenat Atcha, Edward R. Browne, Lee Sun New, Chiu Cheong Aw, Catherine Wenhui Goh, Woei Shin Chen, Eric Chun Yong Chan, Dilys P Q Goh, Aveline H. Neo
Publikováno v:
Journal of Proteome Research. 8:5679-5690
In this study, the correlation between the metabolic profiles of rats undergoing cognition enhancement drug therapy and their associated cognitive behavioral outcomes were investigated. Male Lister Hooded rats were administered either with donepezil,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fb122fff0b1d7a51cb7ea29b3518e4
https://doi.org/10.1021/pr900795g
https://doi.org/10.1021/pr900795g
Autor:
Sumitra Ramachandran, Angela A. Dunne, Neil Derek Miller, Laiq Chaudry, Vincent Jaquet, Craig Allan, Aleksandra Filippova, Jean Lim, Ceri H. Davies, Agnes B. Ong, May Thu Ma, Shabina Nasir, Woei Shin Chen, Nicole Y. Ye, Edward R. Browne, Kiew Ching K Lee, Shihua Liao, Douglas G. Johns, Angela Bridges, Yasuji Matsuoka, Chiu Cheong Aw, A. Richard Rutter, Adeline L.W. Chueng, Dizheng Li, Deborah W. Chen, Sri Mulyanidewi, Sarah Duncan, Tamara Seredenina, Gary Pettman, Kazufumi Hirano, Pamela P. Oon
Publikováno v:
Antioxidants & redox signaling, Vol. 23, No 5 (2015) pp. 358-374
Aims: The NADPH oxidase (NOX) family of enzymes catalyzes the formation of reactive oxygen species (ROS). NOX enzymes not only have a key role in a variety of physiological processes but also contribute to oxidative stress in certain disease states.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7ea3e136424a97ddab898f120e2665
https://europepmc.org/articles/PMC4545375/
https://europepmc.org/articles/PMC4545375/
Autor:
Kazufumi Hirano, Kirsten L. Searle, Shabina Nasir, A. Richard Rutter, Edward R. Browne, Chiu-Cheong Aw
Publikováno v:
Neuroscience letters. 503(3)
The 5-HT(6) receptor subtype is predominantly expressed in the central nervous system, and preclinical evidence suggests that it plays a critical role in the regulation of molecular pathways underlying cognitive function. Patients with schizophrenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdc6ffeaf050a48b09c8ef96bcfc37d
https://pubmed.ncbi.nlm.nih.gov/21896308
https://pubmed.ncbi.nlm.nih.gov/21896308
Autor:
Eric Chun Yong Chan, Kai Lun Chang, Edward R. Browne, Chiu Cheong Aw, Catherine W. Goh, Lee Sun New, Mainak Mal
Publikováno v:
Journal of proteome research. 10(4)
3-Nitropropionic acid (3-NP), a potent irreversible inhibitor of mitochondrial complex II enzyme, leads to mitochondrial dysfunction and oxidative stress in Huntington's disease (HD) rat model. In this study, biochemical assays were used to demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c20d6dbc542473f0d3725513b80717
https://pubmed.ncbi.nlm.nih.gov/21355552
https://pubmed.ncbi.nlm.nih.gov/21355552
Autor:
Dilys P. Q. Goh, Aveline H. Neo, Catherine W. Goh, Chiu Cheong Aw, Lee Sun New, Woei Shin Chen, Zeenat Atcha, Edward R. Browne, Eric C. Y. Chan
Publikováno v:
Journal of Proteome Research; Dec2009, Vol. 8 Issue 12, p5679-5690, 12p