Výsledky vyhledávání

Akademický článek

A GSTP1-mediated lactic acid signaling promotes tumorigenesis through the PPP oxidative branch

Autor: Yandi Sun, Qian He, Jingjia Li, Ze Yang, Mashaal Ahmad, Yindan Lin, Di Wu, Lei Zheng, Jiangtao Li, Ben Wang, Chitty Chen, Yue Hu, Heng Luo, Yan Luo

Publikováno v: Cell Death and Disease, Vol 14, Iss 7, Pp 1-15 (2023)

Abstract Lactic acidosis is a feature of solid tumors and plays fundamental role(s) rendering cancer cells to adapt to diverse metabolic stresses, but the mechanism underlying its roles in redox homeostasis remains elusive. Here we show that G6PD is

Externí odkaz: https://doaj.org/article/55cd5c0c7c794f52ac39dc7e06e1b2de

Zobrazit plný text záznamu

A Predictive Model Using N-Glycan Biosignatures for Clinical Diagnosis of Early Hepatocellular Carcinoma Related to Hepatitis B Virus

Publikováno v: OMICS: A Journal of Integrative Biology. 24:415-423

Early diagnosis of hepatic cancer is a major public health challenge. While changes in serum N-glycans have been observed as patients progress from liver fibrosis/cirrhosis to hepatocellular carcinoma (HCC), the predictive performance of N-glycans is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3abb223a7374c73d8ef9d562e0f444d
https://doi.org/10.1089/omi.2020.0055

Zobrazit plný text záznamu

Alteration of liver N-glycome in patients with hepatocellular carcinoma

Autor: Sylviane Dewaele, Claude Libert, Xue-En Liu, Valerie Vanhooren, Feng-Min Lu, Cuiying Chitty Chen, Hui Zhuang, Ling Wang

Publikováno v: OPEN JOURNAL OF GASTROENTEROLOGY

Purpose: Alteration of liver function during pro- gression of hepatocellular carcinoma (HCC) and cirrhosis affects the serum glycoprotein pattern. In this study, the changes in the N-glycome in liver tis- sue from patients with hepatocellular carcino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f9526f7e4b8e8d0657d9478e0baafdb
https://doi.org/10.4236/ojgas.2012.21001

Zobrazit plný text záznamu

Alteration in N-glycomics during mouse aging: a role for FUT8

Autor: Laurent Dollé, Claude Libert, Evgenia Makrantonaki, Naoyuki Taniguchi, Sylviane Dewaele, Valerie Vanhooren, Christos C. Zouboulis, Cuiying Chitty Chen, Makoto Kuro-o, Leo A. van Grunsven

Publikováno v: Aging Cell. 10:1056-1066

We recently reported that N-glycosylation changes during human aging. To further investigate the molecular basis determining these alterations, the aging process in mice was studied. N-glycan profiling of mouse serum glycoproteins in different age gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00502ad51232e3d6288ac75126334b09
https://doi.org/10.1111/j.1474-9726.2011.00749.x

Zobrazit plný text záznamu

Alteration of N-glycome in diethylnitrosamine-induced hepatocellular carcinoma mice: a non-invasive monitoring tool for liver cancer

Autor: Roland Contreras, Xue-En Liu, Valerie Vanhooren, Cuiying Chitty Chen, Sylviane Dewaele, Jacques Van Huysse, Claude Libert, Ye-Dong Fan, Hui Zhuang, Ling Wang

Publikováno v: Liver International. 30:1221-1228

Background and aims: There is a demand for serum markers that can routinely assess the progression of liver cancer. DENA (diethylnitrosamine), a hepatocarcinogen, is commonly used in an experimental mouse model to induce liver cancer that closely mim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c719d2037a18c5de0f6b2add75478b5
https://doi.org/10.1111/j.1478-3231.2010.02279.x

Zobrazit plný text záznamu

N-glycomic biomarkers of biological aging and longevity: A link with inflammaging

Autor: Manfred Wuhrer, Fabio Dall'Olio, Cuiying Chitty Chen, P. Eline Slagboom, Valerie Vanhooren, Claudio Franceschi

Publikováno v: Ageing Research Reviews, 12(2), 685-698

Glycosylation is a frequent co/post-translational modification of proteins which modulates a variety of biological functions. The analysis of N-glycome, i.e. the sugar chains N-linked to asparagine, identified new candidate biomarkers of aging such a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96515ba161d089f3063c5c57c351a046
http://hdl.handle.net/11585/139812

Zobrazit plný text záznamu

Human serum N-glycan profiles are age and sex dependent

Autor: Xue Liang, Xia Liu, Huan Nie, Xuemei Sun, Cuiying Chitty Chen, Youpeng Qu, Wei Sun, Yuanfei Yao, Yu Li, Ning Ding

Publikováno v: Age and Ageing; Vol 40

Background: protein glycosylation varies with the physiological and pathological status of the cell. Consequently, analysis of protein-linked glycans has growing importance both in basic glycobiological research and as a potential tool for monitoring

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd756b8b66fbed048557d7fff7cf646
https://pubmed.ncbi.nlm.nih.gov/21807702

Zobrazit plný text záznamu

Serum N-glycan profile shift during human ageing

Autor: Cuiying Chitty Chen, Sylviane Dewaele, Peter Paul De Deyn, Koos Jaspers, Florence Debacq-Chainiaux, Ingrid van der Pluijm, Michel Poulain, Jan H.J. Hoeijmakers, Olivier Toussaint, Sebastiaan Engelborghs, Youri Glupczynski, Claude Libert, Claudio Franceschi, Valerie Vanhooren

Publikováno v: Experimental Gerontology, 45(10), 738-743. Elsevier Inc.
Experimental gerontology
Experimental Gerontology; Vol 45
Experimental Gerontology
Experimental Gerontology, Elsevier, 2010, 45 (10), pp.738. ⟨10.1016/j.exger.2010.08.009⟩

Biomarkers indicating biological age are of significant interest for prevention, diagnosis and monitoring (and the treatment) of age-related diseases. We previously reported an alteration of serum N-glycan profile in old humans using "DNA Sequencer A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e5f34efc7ad12456437178a963e25e
https://pure.eur.nl/en/publications/9d1f3106-cec1-4ac5-a187-26fad25e4249

Zobrazit plný text záznamu

Altered serum glycomics in Alzheimer disease

Autor: Peter Paul De Deyn, Nathalie Le Bastard, Jean-Jacques Martin, Sebastiaan Engelborghs, Claude Libert, Sylviane Dewaele, Valerie Vanhooren, Cuiying Chitty Chen

Publikováno v: Rejuvenation research

We investigated whether blood N-glycan changes can be used as a diagnostic biomarker for Alzheimer disease (AD). We used DNA sequencer-assisted, fluorophore-assisted carbohydrate electrophoresis (DSA-FACE) technology to assay N-glycans in sera from 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6dd9f6fe2953d4bed928f9e07fb0ce
https://biblio.vub.ac.be/vubir/(039ba11e-e1ec-4e8c-84b7-c80bf0e8b2fe).html

Zobrazit plný text záznamu

Alteration of N-glycome in diethylnitrosamine-induced hepatocellular carcinoma mice: a non-invasive monitoring tool for liver cancer

Autor: Xue-en, Liu, Sylviane, Dewaele, Valerie, Vanhooren, Ye-Dong, Fan, Ling, Wang, Jacques, Van Huysse, Hui, Zhuang, Roland, Contreras, Claude, Libert, Cuiying Chitty, Chen

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver. 30(8)

There is a demand for serum markers that can routinely assess the progression of liver cancer. DENA (diethylnitrosamine), a hepatocarcinogen, is commonly used in an experimental mouse model to induce liver cancer that closely mimics a subclass of hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::475aaa73d48b83f4e3e8ed8c71bff938
https://pubmed.ncbi.nlm.nih.gov/20524982

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání