Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Chitta R. Dey"'
Publikováno v:
Journal of Biological Chemistry. 277:38709-38713
Surfactant protein D (SP-D) gene-targeted mice develop severe pulmonary disease associated with emphysema, pulmonary lipidosis, and foamy macrophage infiltrations. To determine the potential reversibility of these abnormalities, transgenic mice were
Publikováno v:
Developmental Dynamics. 210:305-314
Hepatocyte nuclear factor-3β (HNF-3β), a nuclear protein of the winged helix family of transcription factors, is known to play a critical role in the formation of the embryonic node, notochord, and foregut endoderm. HNF-3β influences the expressio
Autor:
Barbara B. Warner, Jean C. Clark, Stephan W. Glasser, Jonathan R. Wispé, Ling-Yi Chang, Chitta R. Dey, J. D. Crapo, J. Neuman, Jeffrey A. Whitsett
Publikováno v:
Journal of Biological Chemistry. 267:23937-23941
To test directly whether mitochondrial Mn-superoxide dismutase (Mn-SOD) protects the lung epithelium from oxygen-induced injury, transgenic mice were produced in which the expression of human Mn-SOD mRNA was directly by transcriptional elements from
Autor:
Jeffrey A. Whitsett, Chitta R. Dey, Barry R. Stripp, Kathryn A. Wikenheiser, Jean C. Clark, Susan E. Wert, Richard J. Gregory, Alan E. Smith, Jonathan A. Cohn, James M. Wilson, John Engelhardt
Publikováno v:
Nature Genetics. 2:13-20
Human cystic fibrosis transmembrane conductance regulator (CFTR) was expressed in transgenic mice under the control of transcriptional elements derived from the human surfactant protein C (SP-C) gene. The hCFTR mRNA was expressed in lungs and testes:
Autor:
Jamie L. Wooldridge, Bruce J. Aronow, Jean C. Clark, Cong Liu, Chitta R. Dey, Yan Xu, Jeffrey A. Whitsett
Publikováno v:
The Journal of biological chemistry. 278(9)
Cystic fibrosis, the most commonly inherited lethal pulmonary disorder in Caucasians, is caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). To identify genomic responses to the presence or absence of CFTR in p
Autor:
William H. Colledge, Kim M. Keeling, Martin J. Evans, Eric J. Sorscher, David M. Bedwell, Ming Du, Jessica Lanier, Jeffrey A. Whitsett, Zsuzsa Bebok, Julie R. Jones, Chitta R. Dey, Albert Tousson, Russell Lindsey
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 80(9)
Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Since approximately 5% of all mutant CF alleles are stop mutations, it can be calculated that approximately 10% o
Autor:
Raymond A. Frizzell, Susan E. Wert, Michael D. DuVall, Chitta R. Dey, Jeffrey A. Whitsett, Lan Zhou
Publikováno v:
Science (New York, N.Y.). 266(5191)
Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). A potential animal model of CF, the CFTR-/- mouse, has had limited utility because most mice die from intestinal obstruct
Publikováno v:
Hazardous Waste and Hazardous Materials. 2:131-141
Yeasts are eukaryotic microorganisms whose cytochrome P-450 monooxygenase systems may be amenable to genetic engineering for the hydroxylation and detoxication of polychlorinated aromatic ...
Autor:
Stanley G. Williams, Nancy C. Ramundo, Chatrchai Watanakunakorn, Carol A. Kauffman, Chitta R. Dey, John P. Phair
Publikováno v:
Antimicrobial Agents and Chemotherapy. 13:918-923
Aerobic gram-negative bacilli isolated from clinical specimens from 1 January to 31 December 1976 were tested for gentamicin and tobramycin resistance by standardized disk testing. For Pseudomonas isolates, gentamicin resistance was 17.1% and tobramy
Autor:
Thomas R. Sutter, Connie W. Woods, John C. Loper, Thomas G. Turi, Chitta R. Dey, Vernon F. Kalb
Publikováno v:
DNA. 6:529-537
We have sequenced the structural gene and flanking regions for lanosterol 14 alpha-demethylase (14DM) from Saccharomyces cerevisiae. An open reading frame of 530 codons encodes a 60.7-kDa protein. When this gene is disrupted by integrative transforma