The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells

Autor: Chitranjan J Shukla, Michael P. Rimmer, Maria E. Camacho-Moll, Leendert H. J. Looijenga, Joni Macdonald, Roland Donat, Rod T. Mitchell, Anne Jorgensen, John A. Marwick, Neil O. Carragher

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
BMC Cancer, 19(1):1124. BioMed Central Ltd.
Camacho-moll, M E, Macdonald, J, Looijenga, L H J, Rimmer, M P, Donat, R, Marwick, J A, Shukla, C J, Carragher, N, Jørgensen, A & Mitchell, R T 2019, ' The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells ', BMC Cancer, vol. 19, no. 1 . https://doi.org/10.1186/s12885-019-6340-7
BMC Cancer

Background Testicular germ cell cancer (TGCC) develops from pre-malignant germ neoplasia in situ (GCNIS) cells. GCNIS originates from fetal gonocytes (POU5F1+/MAGE-A4−), which fail to differentiate to pre-spermatogonia (POU5F1−/MAGE-A4+) and unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c7d5f24575e9d7b52e96d3bcb218f4
http://link.springer.com/article/10.1186/s12885-019-6340-7

BAUS consensus document for the management of male genital emergencies: priapism

Autor: Trevor J. Dorkin, Chitranjan J Shukla, Gareth Brown, Majid Shabbir, Asif Muneer, Marc Lucky, Duncan J. Summerton, Richard Pearcy, Rowland W. Rees

Publikováno v: BJU International. 121:835-839

Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9f347529df7d6b7e4ebe9e15cf474c
https://doi.org/10.1111/bju.14140

British Association of Urological Surgeons (BAUS) consensus document for the management of male genital emergencies - penile amputation

Autor: Chitranjan J, Shukla, Gareth, Brown, Trevor, Dorkin, Marc, Lucky, Richard, Pearcy, Rowland W, Rees, Majid, Shabbir, Duncan J, Summerton, Asif, Muneer, Raj, Nigam

Publikováno v: BJU International. 121:699-702

Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c86e23904090815d00c0c5e3613becd
https://doi.org/10.1111/bju.14135

Surgical management of azoospermia: can the NHS England Clinical Commissioning Policy reduce geographical inequality of services?

Autor: Marc Lucky, Asif Muneer, Rowland W. Rees, Richard Pearcy, Chitranjan J Shukla, Trevor J. Dorkin, Duncan J. Summerton, Majid Shabbir, Gareth Brown

Publikováno v: BJU international. 121(2)

Developments in assisted reproductive techniques (ART) have transformed the management of male factor infertility and the advent of intracytoplasmic sperm injection (ICSI) in 1993 was a landmark in the management of the infertile male. While this has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274ce9a03bb018b28c3ad3f3252bc919
https://pubmed.ncbi.nlm.nih.gov/29105258

Laser-capture microdissection in prostate cancer research: establishment and validation of a powerful tool for the assessment of tumour–stroma interactions

Autor: Chitranjan J. Shukla, Richard Y. Ball, Krishna Sethia, Dylan R. Edwards, Caroline J. Pennington, Antony C. P. Riddick

Publikováno v: BJU International. 101:765-774

OBJECTIVES To describe our experience with the optimization and validation of laser-capture microdissection (LCM) for biomarker analysis in prostate tissues. As LCM allows the separation of benign and malignant epithelial structures and stromal eleme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec49a835a9091b11934a9cfeb7d4fbb0
https://doi.org/10.1111/j.1464-410x.2007.07372.x